Description

This groundbreaking work, now available in paperback, has helped to shape the emerging discipline of molecular epidemiology. Molecular Epidemiology has proven useful to epidemiologists unfamiliar with the terminology and techniques of molecular biology as well as to the molecular biologist working to understand the determinants of human disease and to use that information to control disease. This book demonstrates how molecular epidemiology utilizes the same paradigm as traditional epidemiology in addition to using biological markers to identify exposure, disease, or susceptibility.

Readership

Graduate students and researchers in epidemiology and molecular biology, cancer researchers, and medical residents.

Table of Contents

Contributors. Preface. General Principles: A Conceptual and Historical Framework for Molecular Epidemiology, P.A. Schulte. Molecular Biology in Epidemiology, R. Hurst and J.Y. Rao. Validation, P.A. Schulte and F.P. Perera. Technical Variability in Laboratory Data, P. Vineis, P.A. Schulte, R.F. Vogt, Jr.. Biological Monitoring and Pharmacokinetics Modeling for the Assessment of Exposure, P.O. Droz. Design Considerations in Molecular Epidemiology, P.A. Schulte, N. Rothman, and D. Schottenfeld. Statistical Issues and Procedures, V.S. Hertzberg and E. Russek-Cohen. Biological Specimen Banks: A Resource for Molecular Epidemiologic Studies, D.M. Winn and E.W. Gunter. Interpretation and Communication of Results, P.A. Schulte. Use of Biomarkers in Risk Assessment. Practical Applications, D. Hattis and K. Silver. Practical Applications: Carcinogenesis, F.P. Perera and R. Santella. Infectious Disease, L.H. Harrison and D.E. Griffin. Cardiovascular Disease, P.A. Schulte, N. Rothman, and M.A. Austin. Genetic Disease, M.J. Khoury and J.S. Dorman. Biologic Markers in the Epidemiology of Reproduction, G.K. Lemasters and P.A. Schulte. Immune Markers in Epidemiologic Field Studies, R.F. Vogt, Jr. and P.A. Schulte. Biomarkers of Pulmonary Disease, M.S. Tockman, P.K. Gupta, N.J. Pressman and J.L. Mulshine. Pulmonary Disease. Biologic Markers in the Genitourinary System, G.P. Hemstreet, III, R.E. Hurst and N.R. Asal. Neurologic Disease, J.D. Griffith and V.F. Garry.

Details

No. of pages:
588
Language:
English
Copyright:
© 1993
Published:
Imprint:
Academic Press
Print ISBN:
9780126323467
Electronic ISBN:
9780080925660

About the authors

Paul Schulte

Dr. Schulte is an epidemiologist with interests in education, quantitative risk assessment, health communication, use of biological markers in epidemiologic research, intervention research, and genetics. In recent years, he has conducted extensive research on occupational cancer. He has focused on issues of dissemination of occupational safety and health information. Dr. Schulte is the editor of the textbook entitled, “Molecular Epidemiology: Principles and Practices.” He has served as guest editor of the Journal of Occupational Medicine and the American Journal of Industrial Medicine and was on the initial editorial board of Cancer Epidemiology, Biomarkers and Prevention. He also has served as a consultant to various organizations such as the International Agency for Research on Cancer, the National Academy of Sciences, the Medical Research Council of the United Kingdom, WHO, the Pennsylvania Department of Health, the Agency for Toxic Substances and Disease Registry, and the Department of Energy.

Reviews

@qu:"The book is an excellent review of the crucial issues related to the incorporation of new markers of exposure, disease, or susceptibility into epidemiologic investigations... This book is an excellent resource for all researchers involved in the quest to understand the determinants of disease and apply this knowledge to the maintenance of the health of the public." @source:--SCIENCE