Molecular Assembly in Natural and Engineered Systems - 1st Edition - ISBN: 9780124159068, 9780124159297

Molecular Assembly in Natural and Engineered Systems, Volume 103

1st Edition

Serial Volume Editors: Stefan Howorka
eBook ISBN: 9780124159297
Hardcover ISBN: 9780124159068
Imprint: Academic Press
Published Date: 26th October 2011
Page Count: 414
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Table of Contents



Chapter 1: Bacterial Microcompartments

I. Introduction

II. Bacterial Microcompartment Form and Function

III. Shell Proteins: Structures and Mechanisms

IV. Higher-Level Organization

V. Future Directions for Research and Design Applications

VI. Closing Remarks

Chapter 2: Pili and Flagella

II. Pili in Gram-Negative Bacteria

III. Pili in Gram-Positive Bacteria

IV. Surface Filaments in Archaea

V. Flagella

VI. Applications

Chapter 3: The Structure of Bacterial S-Layer Proteins

II. Geobacillus stearothermophilus

III. Clostridia

IV. Lactobacilli

V. Bacillus anthracis

VI. Lysinibacillus sphaericus

VII. Corynebacterium glutamicum

VIII. Deinococcus–Thermus

IX. S-Layers from Gram-Negative Bacteria

X. Concluding Remarks

Chapter 4: Spider Silk

II. Spiders

III. Nomenclature of Silk Types

IV. Set-up of Silk Proteins

V. Major Ampullate Silk (aka Dragline Silk, Lifeline Silk) and Minor Ampullate Silk

VI. Flagelliform Silk (aka Capture Silk and Viscid Silk)

VII. Pseudoflagelliform Silk and Cribellate Silk

VIII. Aciniform Silk

IX. Tubiliform Silk (aka Cylindriform Silk)

X. Egg Case Proteins

XI. Aggregate Silk (aka Glue)

XII. Pyriform Silk

XIII. Silk Summary

XIV. Producing Recombinant Silk Proteins

XV. Future Outlook

Chapter 5: Protein Modifications Giving Rise to Homo-oligomers

I. Proteins as Building Blocks

II. Hetero- Versus Homo-oligomers

III. Symmetric Associations

IV. Lessons from Protein Crystallization

V. The Analysis of Known Protein–Protein Contacts

VI. Self-assembly in Nature

VII. Self-assembling Protein Constructs

VIII. Design of Protein–Protein Contacts

IX. Future A


This volume explores some of the most exciting recent advances in basic research on molecular assembly in natural and engineered systems and how this knowledge is leading to advances in the various fields.

Key Features

  • This series provides a forum for discussion of new discoveries, approaches, and idea
  • Contributions from leading scholars and industry experts
  • Reference guide for researchers involved in molecular biology and related fields


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.


No. of pages:
© Academic Press 2011
Academic Press
eBook ISBN:
Hardcover ISBN:


Praise for the series:
"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

Ratings and Reviews

About the Serial Volume Editors

Stefan Howorka Serial Volume Editor