Methods in Psychobiology

Methods in Psychobiology

Specialized Laboratory Techniques in Neuropsychology and Neurobiology

1st Edition - January 1, 1972

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  • Editor: R. D. Myers
  • eBook ISBN: 9781483268293

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Description

Methods in Psychobiology, Volume 2, Specialized Laboratory Techniques in Neuropsychology and Neurobiology is intended for the beginning ""student"" in physiological, neuro-, bio-psychology, or whatever label one wishes to attach to the exciting interdisciplinary field which weds the brain and behavior. In contrast to Volume 1, somewhat more emphasis is given in the selection of topics to a number of difficult behavioral methods that are used frequently by individuals in the more traditional neurosciences. The book begins with a discussion of the measurement of behavioral activity. This is followed by separate chapters on techniques such as electric shock motivation; aversive learning; methods of assessing the behavioral effects of drugs; long-term intravenous infusions; and perfusion of different parts of the brain. Subsequent chapters deal with the assay of pharmacologically active substances; the split-brain technique; using microknives in brain lesion studies and the production of isolated brain-stem islands; the functional decortication technique; and recording evoked potentials.

Table of Contents


  • List of Contributors

    Preface

    Chapter 1 Measuring Behavioral Activity

    I. Introduction

    II. Methods of Measurement

    III. The Revolving Wheel

    IV. Stabilimeter and Stationary-Cage Recording

    V. Conclusions

    Acknowledgment

    References

    Appendix

    Chapter 2 Techniques of Electric Shock Motivation

    I. Apparatus for Delivering the Shock to the Subject

    II. Shock Sources: General Considerations

    III. Types of Shock Sources

    IV. Shock Scramblers

    V. Factors Which Can Attenuate Grid Floor Shock

    VI. Basic Techniques for the Measurement and Control of Electric Shock Motivation

    References

    Chapter 3 Aversive Learning Situations: Apparatus and Procedures

    I. Introduction

    II. Instrumental Aversive Situations

    References

    Appendix

    Chapter 4 Assessing the Effect of Drugs

    I. Introduction

    II. Pharmacological Considerations

    III. Behavioral Considerations

    References

    Appendix

    Chapter 5 Manipulation of the Oral and Gastric Environments

    I. Origin and Application of Techniques

    II. Methods

    III. Future Applications

    Acknowledgments

    References

    Appendix

    Chapter 6 Long-Term Intravenous Infusion

    I. Introduction

    II. Saddle and Feedthrough Swivel

    III. Cannula Construction

    IV. Surgical Procedure

    V. Trouble Shooting and Special Arts

    References

    Appendix

    Chapter 7 Methods for Perfusing Different Structures of the Brain

    I. Introduction

    II. Perfusing the Cerebral Ventricles

    III. Isolated Tissue Perfusion with Push-Pull Cannulae

    IV. Perfusion of the Cortex

    V. Theoretical Considerations

    References

    Appendix

    Chapter 8 The Neurobiological Assay

    I. Introduction

    II. Identification by Pharmacological Analysis

    III. Recording the Contractions of Isolated Smooth and Striated Muscles

    IV. The Bioassay of Acetylcholine

    V. The Bioassay of 5-Hydroxytryptamine (Serotonin)

    VI. The Bioassay of Catecholamines

    References

    Appendix

    Chapter 9 Specialized Lesions: the Split-Brain Technique

    I. Historical Introduction

    II. Surgical Methods

    III. Post-Surgical Care

    IV. Histological Verification of Surgery

    V. Fabrication of Instruments for Split-Brain Surgery

    VI. Behavioral Testing Methods

    References

    Appendix

    Chapter 10 Specialized Lesions: "Cerveau Isolé" and "Encephale Isolé"

    I. Introduction

    II. The "Cerveau Isolé"

    III. The "Encephale Isolé"

    IV. Maintenance and Nursing Care

    V. The Use of the Preparations for Psychobiology

    References

    Appendix

    Chapter 11 The Use of Microknives in Brain Lesion Studies and the Production of Isolated Brain-Stem Islands

    I. Brain Lesions: General Considerations

    II. The Usefulness of Microknives

    III. The Hypothalamic Island

    IV. Design and Construction of Knives

    V. The Hypothalamic Island: Procedures and Post-Operative Care

    References

    Appendix

    Chapter 12 Inducing Cortical Spreading Depression

    I. Introduction

    II. Semi-Chronic Technique

    III. Chronic Technique

    IV. Main Fields of Application

    References

    Appendix

    Chapter 13 Recording Evoked Potentials

    I. Introduction

    II. The Recording Situation

    III. Stimulus Generators

    IV. Installation of Electrodes in Humans and Animals

    V. Evaluation of Evoked Potential Data

    References

    Appendix

    Author Index

    Subject Index

Product details

  • No. of pages: 410
  • Language: English
  • Copyright: © Academic Press 1972
  • Published: January 1, 1972
  • Imprint: Academic Press
  • eBook ISBN: 9781483268293

About the Editor

R. D. Myers

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