Metabolomics

A Path Towards Personalized Medicine

1st Edition - December 1, 2022

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Author: Mahbuba Rahman
Paperback ISBN: 9780323999243

View series: Developments in Applied Microbiology and Biotechnology

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Description

Metabolomics: A Path Towards Personalized Medicine integrates environmental factors of genomics, transcriptomics and proteomics, providing a bridge to resolve gaps between fundamental science and applications in clinical medicine and population health. The concept of personalized medicine or precision medicine is of great interest in biomedical research as it helps bring about new drug discovery and biomarker identification. In addition, it helps clinicians prescribe the right medicine to the right person with maximum efficacy and minimum toxicity, allowing clinicians to further predict the susceptibility to disease onset of vulnerable populations.The book is ideally suited for researchers and postgraduate students who are interested in clinical and non-clinical studies where metabolites are used for the identification of disease and therapeutic targets.

Key Features

Gives insights on the importance of personalized medicine in clinical and research environments
Provides the principles of metabolomics
Presents applications of metabolomics in biomarker identification and drug discovery

Readership

Students, Academics, Clinicians, Researchers in clinical and non-clinical studies, biochemistry clinical microbiology and systems biology; Students and Biotech companies for Drug discovery and biomarker identification panels in infectious disease and non-infectious disease

1. Personalized medicine
Abstract
Introduction
Current challenges with conventional treatment
Components of personalized medicine
Conclusion
References

2. Metabolomics
Abstract
Introduction
Platforms and equipment used for metabolomics
Conclusion
References

3. Metabolomics used in clinical diagnosis related to infectious disease
Abstract
Introduction
Metabolomics for infectious disease and management
Conclusion
References

4. Metabolomics used in clinical diagnosis related to new-born screening
Abstract
Introduction
Metabolites related to inborn errors of immunity
Conclusion
References

5. Identification of Biomarkers for non-infectious disease
Abstract
Introduction
Metabolites associated with non-infectious disease-cancer, cardiovascular disease, neurological disorder
Conclusion
References

6. Magnetic resonance imaging of Metabolites for precision medicine
Abstract
Introduction
Diseases diagnosed with magnetic resonance imaging
Conclusion
References

7. Industrial application of metabolomics in drug discovery and biomarker identification
Abstract
Introduction
Current challenges with drug discovery and biomarker identification
Metabolomics for drug discovery and biomarker identification
Conclusion
References

Product details

No. of pages: 466
Language: English
Published: December 1, 2022
Imprint: Academic Press
Paperback ISBN: 9780323999243

About the Author

Mahbuba Rahman

Dr. Mahbuba Rahman earned her B.Sc. (Honors) and M. Sc in Microbiology and an M.S in Environmental Science. She completed her PhD in Metabolic Engineering from the Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Japan. Post PhD, she worked with transgenic mice model of Smith–Lemli–Opitz syndrome, which is an inborn error of cholesterol synthesis, at Children’s Hospital Research Institute (CHORI), Oakland, California. She is involved with multiple translational projects including identification of biomarkers for colon cancer. Very recently, she has been involved with the application of phage display technology in clinical research to investigate immune response against different viral species in primary immunodeficient patients, association of virus infection and obesity, and role of stress responsive genes in pathogenic bacteria. Mahbuba has published several research articles including clinical and non-clinical research in high impact factor journals. She also authored multiple review articles and book chapters in high impact journals and well-known publishers. She is also an editor of an eBook on cancer immunotherapy and special topic editor and guest editor in Frontiers in Genetics.

Affiliations and Expertise

McMaster University, Hamilton, Ontario, Canada

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