Metabolomics

Metabolomics

A Path Towards Personalized Medicine

1st Edition - December 1, 2022

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  • Editor: Mahbuba Rahman
  • Paperback ISBN: 9780323999243

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Description

Metabolomics: A Path Towards Personalized Medicine integrates environmental factors of genomics, transcriptomics and proteomics, providing a bridge to resolve gaps between fundamental science and applications in clinical medicine and population health. The concept of personalized medicine or precision medicine is of great interest in biomedical research as it helps bring about new drug discovery and biomarker identification. In addition, it helps clinicians prescribe the right medicine to the right person with maximum efficacy and minimum toxicity, allowing clinicians to further predict the susceptibility to disease onset of vulnerable populations.The book is ideally suited for researchers and postgraduate students who are interested in clinical and non-clinical studies where metabolites are used for the identification of disease and therapeutic targets.

Key Features

  • Gives insights on the importance of personalized medicine in clinical and research environments
  • Provides the principles of metabolomics
  • Presents applications of metabolomics in biomarker identification and drug discovery

Readership

Students, Academics, Clinicians, Researchers in clinical and non-clinical studies, biochemistry clinical microbiology and systems biology; Students and Biotech companies for Drug discovery and biomarker identification panels in infectious disease and non-infectious disease

Table of Contents

  • 1. Personalized medicine
    Abstract
    Introduction
    Current challenges with conventional treatment
    Components of personalized medicine
    Conclusion
    References

    2. Metabolomics
    Abstract
    Introduction
    Platforms and equipment used for metabolomics
    Conclusion
    References

    3. Metabolomics used in clinical diagnosis related to infectious disease
    Abstract
    Introduction
    Metabolomics for infectious disease and management
    Conclusion
    References

    4. Metabolomics used in clinical diagnosis related to new-born screening
    Abstract
    Introduction
    Metabolites related to inborn errors of immunity
    Conclusion
    References

    5. Identification of Biomarkers for non-infectious disease
    Abstract
    Introduction
    Metabolites associated with non-infectious disease-cancer, cardiovascular disease, neurological disorder
    Conclusion
    References

    6. Magnetic resonance imaging of Metabolites for precision medicine
    Abstract
    Introduction
    Diseases diagnosed with magnetic resonance imaging
    Conclusion
    References

    7. Industrial application of metabolomics in drug discovery and biomarker identification
    Abstract
    Introduction
    Current challenges with drug discovery and biomarker identification
    Metabolomics for drug discovery and biomarker identification
    Conclusion
    References

Product details

  • No. of pages: 466
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: December 1, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780323999243

About the Editor

Mahbuba Rahman

Dr. Mahbuba Rahman earned her B.Sc. (Honors) and M. Sc in Microbiology and an M.S in Environmental Science. She obtained her PhD in Metabolic Engineering from the Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Japan. Post PhD, she worked with transgenic mice model of Smith–Lemli–Opitz syndrome, which is an inborn error of cholesterol synthesis, at Children’s Hospital Research Institute (CHORI), Oakland, California. She is involved with multiple translational projects including identification of biomarkers for colon cancer and application of phage display technology in clinical research to investigate immune response against different viral species in primary immunodeficient patients, association of virus infection and obesity, and role of stress responsive genes in pathogenic bacteria. Mahbuba has published several research articles in high impact factor journals. She also authored multiple review articles and book chapters in high impact factor journals and with well-known publishers. She is also an editor of an eBook on cancer immunotherapy and special topic editor and guest editor in Frontiers in Genetics.

Affiliations and Expertise

McMaster University, Hamilton, Ontario, Canada

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