Membrane Processes in Biotechnology and Pharmaceutics

1st Edition

Authors: Catherine Charcosset
Hardcover ISBN: 9780444563347
eBook ISBN: 9780444563378
Imprint: Elsevier
Published Date: 31st January 2012
Page Count: 350
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Membrane processes are increasingly used in pharmaceutical and biochemical engineering and biotechnology for concentration and purification, synthesis of molecules and drug delivery systems, and support for biochemical reactions. This book provides a state-of-the art overview of the classical membrane processes used in pharmaceutical and biochemical engineering and biotechnology, such as ultrafiltration, microfiltration, virus filtration, membrane chromatography, membrane emulsification, liquid membranes and membrane bioreactors. It describes the general rules (principles, choice of configurations, membranes, parameters, etc.), recent developments (fouling control, increase permeate flux and selectivity, etc.), applications, and theoretical descriptions. Further, it presents emerging processes such as solvent resistant nanofiltration and membrane crystallization.

Key Features

  • Presents classical membrane processes such as ultrafiltration, microfiltration, virus filtration, membrane chromatography, membrane emulsification, liquid membranes and membrane bioreactors
  • Presents emerging processes such as solvent resistant nanofiltration and membrane crystallization
  • Gives a complete description of each technique (principles, membrane materials and devices, fouling control, and theoretical description)
  • Contains numerous examples of applications
  • Includes a uniform notation throughout the book enhancing the presentation and understanding of the content
  • Includes extensive list of references


Primary Market:
Scientists having an interest in membrane processes in pharmaceutical, biotechnological, and chemical engineering. PhD students pharmaceutical, biotechnological, and chemical engineering. Scientific libraries.

Secondary Market:
Membrane companies, pharmaceutical and biotechnological industries.

Table of Contents



1. Principles on membrane and membrane processes

1.1 Membrane materials

1.2 Membrane devices

1.3 Membrane characterization

1.4 Fouling

1.5 Cleaning


2. Ultrafiltration

2.1 Principles

2.2 Membranes

2.3 Fouling control

2.4 Configurations

2.5 Applications

2.6 Theory


3. Microfiltration

3.1 Principles

3.2 Fouling control

3.3 Applications

3.4 Theory


4. Virus filtration

4.1 Principles

4.2 Membranes and configurations

4.3 Fouling

4.4 Applications

4.5 Purification of viral vectors and vaccines

4.6 Theory of virus clearance


5. Membrane chromatography

5.1 Principles

5.2 Membrane support

5.3 Membrane activation

5.4 Interaction mode

5.5 Applications

5.6 Monolith chromatography

5.7 Theory


6. Membranes for the preparation of emulsions and particles

6.1 Principles

6.2 Configurations and membranes

6.3 Applications

6.4 Theory


7. Other membrane processes

7.1 Liquid membranes

7.2 Membrane bioreactors


8. Some perspectives

8.1 Solvent-resistant nanofiltration

8.2 Membrane crystallization




No. of pages:
© Elsevier 2012
eBook ISBN:
Hardcover ISBN:

About the Author

Catherine Charcosset

Catherine Charcosset got her PhD from Compiègne University (France) and then spent 2 years as a postdoctoral fellow at MIT (Boston, USA). She was appointed research scientist at CNRS (Centre National de la Recherche Scientifique, France) first as a junior and then as a senior scientist. Her field of research concerns membrane and membrane processes, especially in biotechnology and pharmaceutics as well as for drinking water treatment. Catherine Charcosset has been (or is) responsible of several national and international projects on membrane and membrane processes. She has supervised 15 PhD students and 20 Master students. She published over 100 papers and chapters in international journals and books and 3 patents. She is the author of one book “Membrane Processes in Biotechnology and Pharmaceutics” published by Elsevier in 2012. She is co-editor with Angelo Basile of another book “Integrated Membrane Systems and Processes” published by Wiley in 2016. She is Executive Editor for the International Journal of Membrane Science and Technology (Editor in chief Angelo Basile).

Affiliations and Expertise

Laboratoire d'Automatique et de Génie des Procédés (LAGEP), Université Claude Bernard Lyon I