Membrane Processes in Biotechnology and Pharmaceutics

1st Edition

Authors: Catherine Charcosset
Hardcover ISBN: 9780444563347
eBook ISBN: 9780444563378
Imprint: Elsevier
Published Date: 31st January 2012
Page Count: 350
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Membrane processes are increasingly used in pharmaceutical and biochemical engineering and biotechnology for concentration and purification, synthesis of molecules and drug delivery systems, and support for biochemical reactions. This book provides a state-of-the art overview of the classical membrane processes used in pharmaceutical and biochemical engineering and biotechnology, such as ultrafiltration, microfiltration, virus filtration, membrane chromatography, membrane emulsification, liquid membranes and membrane bioreactors. It describes the general rules (principles, choice of configurations, membranes, parameters, etc.), recent developments (fouling control, increase permeate flux and selectivity, etc.), applications, and theoretical descriptions. Further, it presents emerging processes such as solvent resistant nanofiltration and membrane crystallization.

Key Features

  • Presents classical membrane processes such as ultrafiltration, microfiltration, virus filtration, membrane chromatography, membrane emulsification, liquid membranes and membrane bioreactors
  • Presents emerging processes such as solvent resistant nanofiltration and membrane crystallization
  • Gives a complete description of each technique (principles, membrane materials and devices, fouling control, and theoretical description)
  • Contains numerous examples of applications
  • Includes a uniform notation throughout the book enhancing the presentation and understanding of the content
  • Includes extensive list of references


Primary Market:
Scientists having an interest in membrane processes in pharmaceutical, biotechnological, and chemical engineering. PhD students pharmaceutical, biotechnological, and chemical engineering. Scientific libraries.

Secondary Market:
Membrane companies, pharmaceutical and biotechnological industries.

Table of Contents



1. Principles on membrane and membrane processes

1.1 Membrane materials

1.2 Membrane devices

1.3 Membrane characterization

1.4 Fouling

1.5 Cleaning


2. Ultrafiltration

2.1 Principles

2.2 Membranes

2.3 Fouling control

2.4 Configurations

2.5 Applications

2.6 Theory


3. Microfiltration

3.1 Principles

3.2 Fouling control

3.3 Applications

3.4 Theory


4. Virus filtration

4.1 Principles

4.2 Membranes and configurations

4.3 Fouling

4.4 Applications

4.5 Purification of viral vectors and vaccines

4.6 Theory of virus clearance


5. Membrane chromatography

5.1 Principles

5.2 Membrane support

5.3 Membrane activation

5.4 Interaction mode

5.5 Applications

5.6 Monolith chromatography

5.7 Theory


6. Membranes for the preparation of emulsions and particles

6.1 Principles

6.2 Configurations and membranes

6.3 Applications

6.4 Theory


7. Other membrane processes

7.1 Liquid membranes

7.2 Membrane bioreactors


8. Some perspectives

8.1 Solvent-resistant nanofiltration

8.2 Membrane crystallization




No. of pages:
© Elsevier 2012
eBook ISBN:
Hardcover ISBN:

About the Author

Catherine Charcosset

Works on membrane and membrane processes, such as the characterization of membranes by confocal microscopy, ultrafiltration and microfiltration, preparation of emulsions and particles, and membrane crystallization for biotechnological, pharmaceutical and environmental applications. She published 50 papers in international journals and deposited 3 patents. She has worked on several academic and industrial projects in the field of membrane and membrane processes.

Affiliations and Expertise

Centre National de la Recherche Scientifique (CNRS), Universite de Lyon, France