Melatonin: Current Status and Perspectives

Melatonin: Current Status and Perspectives

Proceedings of an International Symposium on Melatonin, Held in Bremen, Federal Republic of Germany, September 28-30, 1980

1st Edition - February 27, 1981

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  • Editors: N. Birau, W. Schloot
  • eBook ISBN: 9781483158105

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Advances in the Biosciences, Volume 29: Melatonin – Current Status and Perspectives is a compilation of papers by different authors presented in the Proceedings of an International Symposium on Melatonin, held in Bremen, Federal Republic of Germany on September 28-30, 1980. This volume is divided into six parts, wherein the first part covers the testing methods of melatonin; the use of the status of assay methods of melatonin; and related studies. Part 2 tracks the developments in melatonin histophysiology, with attempts to clarify cytological aspects of the indoleamine secretory process in the pineal gland; melatonin production by extra-pineal tissues; and other relationships with the pineal gland. Part 3 focuses on advances in melatonin physiology from hypothetical evolutionary function; the biochemistry and pharmacology of melatonin; to melatonin and pigment cell rhythmicity. Part 4 shows the progress made in molecular endocrinology, while Part 5 presents the results of human melatonin research and covers melatonin serum in humans. The last part is comprised of additional papers that are not classified in the former categories: studies of the effects of light on human plasma melatonin; the role of the environmental factors; and the histology melatonin localized in the salivary glands of the rat palate. This compilation of papers is intended for biochemists, neuroscientists, and researchers in the fields of endocrinology, human genetics, and pharmaceutical chemistry.

Table of Contents

  • Assay Methods of Melatonin

    Current Status of Assay Methods of Melatonin

    Radioimmunoassay for Human Melatonin

    Melatonin in Human Serum - A Collaborative Study of Current Radioimmunoassays

    Developments in Melaton in Histophysiology

    Cytological Aspects of Indoleamine Secretion in the Pineal Gland

    Melatonin Production by Extra-Pineal Tissues

    Melatonin Biosynthesis in Avian Pineal Gland and Retina

    Melatonin and Other Pineal Products

    A Comparison of Blinding and Afternoon Melatonin Injections on the Histology of the Reproductive Organs, Pineal Ultrastucture and Gonadotrophin Hormone Levels in Female Syrian Hamsters

    A Possible Role for the Pineal Gland and Melatonin in the Diffuse Neuroendocrine System (DNES)

    Advances in Melaton in Physiology

    Evolution of Melatonin Function: a Hypothesis

    New Trends and Perspectives in Melatonin Research

    Physiologic Regulation of Melatonin

    The Pharmacology of Melatonin

    Effect of Light Intensity on Regulation of Melatonin Secretion and Drinking Behavior in the Albino Rat

    Effect of Pinealectomy in the Electrical Responses of Hypothalamic Neurones to the Application of Melatonin

    The Effects of Microelectrophoretically Applied Melatonin, Putative Transmitters, Thyroxine and Sex Hormones on the Electrical Activity of Pineal Cells in the Guinea-Pig

    The Biochemistry and Pharmacology of Melatonin

    Inhibition by Melatonin of Prostaglandin Synthesis in Hypothalamus, Uterus and Platelets

    Reproductive Consequences of Melatonin in Mammals

    Similarities in the Refractoriness of the Reproductive System of Hamsters to Melatonin and to Darkness

    Melatonin Stimulation of Prolactin Secretion in Male Rats: Influence of Pinealectomy, Castration or Gonadal Steroid Pretreatment

    Gonadotropin Inhibiting Activity of Melatonin-Free Pineal Extract

    Melatonin and Biorhythms

    Ontogenic and Phylogenic Aspects of the Circadian Rhythm of Melatonin Synthesis in the Pineal Gland

    Melatonin: Origin, control of Circadian Rhythm and Site of Action

    Annual Bimodal Variation in Human Pineal Hydroxyindole-O-Methyltransferase Activity

    Circadian Rhythmicity in the Activity of HIOMT in the Formation of Melatonin and of 5-Methoxytryptophol in the Retina, Harderian Gland and Pineal of the Male Hamster

    Seasonal Variations in HIOMT Activity during the Night in the Pineal Gland of Wistar Rats of Several Ages

    The Influence of Some Pteridines on the Circadian and Seasonal Rhythmicity of Hydroxyindole-O-Methyltransferase (HIOMT) in the Pineal Gland of 42 Days Old Male Wistar Rats

    Circannual Variations of Serotonin in the Pineal Complex of Ammocoetes Prior to Metamorphosis and Metamorphosing Forms of Lampetra planeri (Petromyzontids)

    Melatonin and Pigment Cell Rhythmicity

    Progress in Molecular Endocrinology of Melatonin

    Molecular Endocrinology of Melatonin: Receptor Sites in Brain and Peripheral Organs

    Molecular Biology of Melatonin: Assessment of the "Microtubule Hypothesis of Melatonin Action"

    Melatonin Receptors in Pineal

    Cyclic Nucleotides and the Mediation of Melatonin-Induced Inhibition of Melanogenesis in Mammals

    New Results in Human Melatonin Research

    Genetics of Melatonin

    Melatonin Rhythms in Human Serum

    Melatonin in Human Serum: Progress in Screening Investigation and Clinic

    Sleep Induction by Intranasal Application of Melatonin

    Liver N-Acetyltransferase Activity and Serum Melatonin in Man

    Melatonin and 5 Methoxytryptophol, the 24 hour Pattern of Secretion in Man

    Melatonin, Vasotocin and Rem Sleep in Prepuberal Boys

    Melatonin in Non-Endocrinological Pathology

    Circadian Rhythms of Melatonin, Prolactin, Growth Hormone and Cortisol in Patients with Pituitary Adenomas, Empty Sella Syndrome and Cushing's Syndrome Due to Adrenal Tumours

    Melatonin in Psychiatric Conditions

    Melatonin in Man

    Appendix - Melatonin and Rebound Phenomenon: A Theoretical Irreversible Thermodynamic Hypothesis

    Additional Papers

    Immunohistological Localization of Melatonin in the Salivary Glands of the Rat

    Human Plasma Melatonin Studies: Effects of Light and Implications for Biological Rhythm Research

    Relative Roles of Environmental Factors, Photoperiod and Temperature in the Control of Serotonin and Melatonin Circadian Variations in the Pineal Organ and Plasma of the Tortoise Testudo hermanni gmelin

    Author Index

    Subject Index

Product details

  • No. of pages: 420
  • Language: English
  • Copyright: © Pergamon 1981
  • Published: February 27, 1981
  • Imprint: Pergamon
  • eBook ISBN: 9781483158105

About the Editors

N. Birau

W. Schloot

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