Melatonin: Current Status and Perspectives

1st Edition

Proceedings of an International Symposium on Melatonin, Held in Bremen, Federal Republic of Germany, September 28-30, 1980

Editors: N. Birau W. Schloot
Hardcover ISBN: 9780080264004
eBook ISBN: 9781483158105
Imprint: Pergamon
Published Date: 27th February 1981
Page Count: 420
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Advances in the Biosciences, Volume 29: Melatonin – Current Status and Perspectives is a compilation of papers by different authors presented in the Proceedings of an International Symposium on Melatonin, held in Bremen, Federal Republic of Germany on September 28-30, 1980. This volume is divided into six parts, wherein the first part covers the testing methods of melatonin; the use of the status of assay methods of melatonin; and related studies. Part 2 tracks the developments in melatonin histophysiology, with attempts to clarify cytological aspects of the indoleamine secretory process in the pineal gland; melatonin production by extra-pineal tissues; and other relationships with the pineal gland. Part 3 focuses on advances in melatonin physiology from hypothetical evolutionary function; the biochemistry and pharmacology of melatonin; to melatonin and pigment cell rhythmicity. Part 4 shows the progress made in molecular endocrinology, while Part 5 presents the results of human melatonin research and covers melatonin serum in humans. The last part is comprised of additional papers that are not classified in the former categories: studies of the effects of light on human plasma melatonin; the role of the environmental factors; and the histology melatonin localized in the salivary glands of the rat palate. This compilation of papers is intended for biochemists, neuroscientists, and researchers in the fields of endocrinology, human genetics, and pharmaceutical chemistry.

Table of Contents

Assay Methods of Melatonin Current Status of Assay Methods of Melatonin Radioimmunoassay for Human Melatonin Melatonin in Human Serum - A Collaborative Study of Current Radioimmunoassays Developments in Melaton in Histophysiology Cytological Aspects of Indoleamine Secretion in the Pineal Gland Melatonin Production by Extra-Pineal Tissues Melatonin Biosynthesis in Avian Pineal Gland and Retina Melatonin and Other Pineal Products A Comparison of Blinding and Afternoon Melatonin Injections on the Histology of the Reproductive Organs, Pineal Ultrastucture and Gonadotrophin Hormone Levels in Female Syrian Hamsters A Possible Role for the Pineal Gland and Melatonin in the Diffuse Neuroendocrine System (DNES) Advances in Melaton in Physiology Evolution of Melatonin Function: a Hypothesis New Trends and Perspectives in Melatonin Research Physiologic Regulation of Melatonin The Pharmacology of Melatonin Effect of Light Intensity on Regulation of Melatonin Secretion and Drinking Behavior in the Albino Rat Effect of Pinealectomy in the Electrical Responses of Hypothalamic Neurones to the Application of Melatonin The Effects of Microelectrophoretically Applied Melatonin, Putative Transmitters, Thyroxine and Sex Hormones on the Electrical Activity of Pineal Cells in the Guinea-Pig The Biochemistry and Pharmacology of Melatonin Inhibition by Melatonin of Prostaglandin Synthesis in Hypothalamus, Uterus and Platelets Reproductive Consequences of Melatonin in Mammals Similarities in the Refractoriness of the Reproductive System of Hamsters to Melatonin and to Darkness Melatonin Stimulation of Prolactin Secretion in Male Rats: Influence of Pinealectomy, Castration or Gonadal Steroid Pretreatment Gonadotropin Inhibiting Activity of Melatonin-Free Pineal Extract Melatonin and Biorhythms Ontogenic and Phylogenic Aspects of the Circadian Rhyth


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© Pergamon 1981
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About the Editor

N. Birau

W. Schloot