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Melatonin: Current Status and Perspectives - 1st Edition - ISBN: 9780080264004, 9781483158105

Melatonin: Current Status and Perspectives

1st Edition

Proceedings of an International Symposium on Melatonin, Held in Bremen, Federal Republic of Germany, September 28-30, 1980

Editors: N. Birau W. Schloot
eBook ISBN: 9781483158105
Imprint: Pergamon
Published Date: 27th February 1981
Page Count: 420
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Advances in the Biosciences, Volume 29: Melatonin – Current Status and Perspectives is a compilation of papers by different authors presented in the Proceedings of an International Symposium on Melatonin, held in Bremen, Federal Republic of Germany on September 28-30, 1980. This volume is divided into six parts, wherein the first part covers the testing methods of melatonin; the use of the status of assay methods of melatonin; and related studies. Part 2 tracks the developments in melatonin histophysiology, with attempts to clarify cytological aspects of the indoleamine secretory process in the pineal gland; melatonin production by extra-pineal tissues; and other relationships with the pineal gland. Part 3 focuses on advances in melatonin physiology from hypothetical evolutionary function; the biochemistry and pharmacology of melatonin; to melatonin and pigment cell rhythmicity. Part 4 shows the progress made in molecular endocrinology, while Part 5 presents the results of human melatonin research and covers melatonin serum in humans. The last part is comprised of additional papers that are not classified in the former categories: studies of the effects of light on human plasma melatonin; the role of the environmental factors; and the histology melatonin localized in the salivary glands of the rat palate. This compilation of papers is intended for biochemists, neuroscientists, and researchers in the fields of endocrinology, human genetics, and pharmaceutical chemistry.

Table of Contents

Assay Methods of Melatonin

Current Status of Assay Methods of Melatonin

Radioimmunoassay for Human Melatonin

Melatonin in Human Serum - A Collaborative Study of Current Radioimmunoassays

Developments in Melaton in Histophysiology

Cytological Aspects of Indoleamine Secretion in the Pineal Gland

Melatonin Production by Extra-Pineal Tissues

Melatonin Biosynthesis in Avian Pineal Gland and Retina

Melatonin and Other Pineal Products

A Comparison of Blinding and Afternoon Melatonin Injections on the Histology of the Reproductive Organs, Pineal Ultrastucture and Gonadotrophin Hormone Levels in Female Syrian Hamsters

A Possible Role for the Pineal Gland and Melatonin in the Diffuse Neuroendocrine System (DNES)

Advances in Melaton in Physiology

Evolution of Melatonin Function: a Hypothesis

New Trends and Perspectives in Melatonin Research

Physiologic Regulation of Melatonin

The Pharmacology of Melatonin

Effect of Light Intensity on Regulation of Melatonin Secretion and Drinking Behavior in the Albino Rat

Effect of Pinealectomy in the Electrical Responses of Hypothalamic Neurones to the Application of Melatonin

The Effects of Microelectrophoretically Applied Melatonin, Putative Transmitters, Thyroxine and Sex Hormones on the Electrical Activity of Pineal Cells in the Guinea-Pig

The Biochemistry and Pharmacology of Melatonin

Inhibition by Melatonin of Prostaglandin Synthesis in Hypothalamus, Uterus and Platelets

Reproductive Consequences of Melatonin in Mammals

Similarities in the Refractoriness of the Reproductive System of Hamsters to Melatonin and to Darkness

Melatonin Stimulation of Prolactin Secretion in Male Rats: Influence of Pinealectomy, Castration or Gonadal Steroid Pretreatment

Gonadotropin Inhibiting Activity of Melatonin-Free Pineal Extract

Melatonin and Biorhythms

Ontogenic and Phylogenic Aspects of the Circadian Rhythm of Melatonin Synthesis in the Pineal Gland

Melatonin: Origin, control of Circadian Rhythm and Site of Action

Annual Bimodal Variation in Human Pineal Hydroxyindole-O-Methyltransferase Activity

Circadian Rhythmicity in the Activity of HIOMT in the Formation of Melatonin and of 5-Methoxytryptophol in the Retina, Harderian Gland and Pineal of the Male Hamster

Seasonal Variations in HIOMT Activity during the Night in the Pineal Gland of Wistar Rats of Several Ages

The Influence of Some Pteridines on the Circadian and Seasonal Rhythmicity of Hydroxyindole-O-Methyltransferase (HIOMT) in the Pineal Gland of 42 Days Old Male Wistar Rats

Circannual Variations of Serotonin in the Pineal Complex of Ammocoetes Prior to Metamorphosis and Metamorphosing Forms of Lampetra planeri (Petromyzontids)

Melatonin and Pigment Cell Rhythmicity

Progress in Molecular Endocrinology of Melatonin

Molecular Endocrinology of Melatonin: Receptor Sites in Brain and Peripheral Organs

Molecular Biology of Melatonin: Assessment of the "Microtubule Hypothesis of Melatonin Action"

Melatonin Receptors in Pineal

Cyclic Nucleotides and the Mediation of Melatonin-Induced Inhibition of Melanogenesis in Mammals

New Results in Human Melatonin Research

Genetics of Melatonin

Melatonin Rhythms in Human Serum

Melatonin in Human Serum: Progress in Screening Investigation and Clinic

Sleep Induction by Intranasal Application of Melatonin

Liver N-Acetyltransferase Activity and Serum Melatonin in Man

Melatonin and 5 Methoxytryptophol, the 24 hour Pattern of Secretion in Man

Melatonin, Vasotocin and Rem Sleep in Prepuberal Boys

Melatonin in Non-Endocrinological Pathology

Circadian Rhythms of Melatonin, Prolactin, Growth Hormone and Cortisol in Patients with Pituitary Adenomas, Empty Sella Syndrome and Cushing's Syndrome Due to Adrenal Tumours

Melatonin in Psychiatric Conditions

Melatonin in Man

Appendix - Melatonin and Rebound Phenomenon: A Theoretical Irreversible Thermodynamic Hypothesis

Additional Papers

Immunohistological Localization of Melatonin in the Salivary Glands of the Rat

Human Plasma Melatonin Studies: Effects of Light and Implications for Biological Rhythm Research

Relative Roles of Environmental Factors, Photoperiod and Temperature in the Control of Serotonin and Melatonin Circadian Variations in the Pineal Organ and Plasma of the Tortoise Testudo hermanni gmelin

Author Index

Subject Index


No. of pages:
© Pergamon 1981
27th February 1981
eBook ISBN:

About the Editors

N. Birau

W. Schloot

Ratings and Reviews