Medicinal Plants

Medicinal Plants

Chemistry, Biology and Omics

1st Edition - June 25, 2015
This is the Latest Edition
  • Authors: Hao Da, Xiao Jie Gu, Pei Gen Xiao
  • eBook ISBN: 9780081001035
  • Hardcover ISBN: 9780081000854

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Description

Medicinal Plants: Chemistry, Biology and Omics reviews the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plant tribes and genera, and their relevance to drug efficacy. Medicinal plants provide a myriad of pharmaceutically active components, which have been commonly used in traditional Chinese medicine and worldwide for thousands of years. Increasing interest in plant-based medicinal resources has led to additional discoveries of many novel compounds, in various angiosperm and gymnosperm species, and investigations on their chemotaxonomy, molecular phylogeny and pharmacology. Chapters in this book explore the interrelationship within traditional Chinese medicinal plant groups and between Chinese species and species outside of China. Chapters also discuss the incongruence between chemotaxonomy and molecular phylogeny, concluding with chapters on systems biology and “-omics” technologies (genomics, transcriptomics, proteomics, and metabolomics), and how they will play an increasingly important role in future pharmaceutical research.

Key Features

  • Reviews best practice and essential developments in medicinal plant chemistry and biology
  • Discusses the principles and applications of various techniques used to discover medicinal compounds
  • Explores the analysis and classification of novel plant-based medicinal compounds
  • Includes case studies on pharmaphylogeny
  • Compares and integrates traditional knowledge and current perception of worldwide medicinal plants

Readership

Researchers and Students in Medicinal plants, Phytochemistry, Pharmacognosy, Pharmacology, Medicinal chemistry and Plant systematics.

Table of Contents

    • Preface
      • Five features of this book
      • Chapter authorship
      • About the authors
    • 1: Chemotaxonomy: a phylogeny-based approach
      • Abstract
      • 1.1 Introduction
      • 1.2 Chemotaxonomic marker
      • 1.3 Metabolomics
      • 1.4 Cheminformatics and database
      • 1.5 Chemotype
      • 1.6 Conclusions
    • 2: High-throughput sequencing in medicinal plant transcriptome studies
      • Abstract
      • 2.1 Introduction
      • 2.2 Metabolic pathway analysis
      • 2.3 Molecular marker mining
      • 2.4 Adaptation and plant development
      • 2.5 Comparative transcriptomics and phylogeny
      • 2.6 Digital gene expression
      • 2.7 Conclusion
    • 3: Taxus medicinal resources: a comprehensive study
      • Abstract
      • Acknowledgments
      • 3.1 Introduction
      • 3.2 From molecular biology to genomics
      • 3.3 Bioactivity, pharmacology, and therapeutic use
      • 3.4 From chemistry to metabolomics
      • 3.5 Proteomics
      • 3.6 Bibliometric analysis of Taxus research
      • 3.7 Conclusion and prospects
    • 4: Phytochemical and biological research of Fritillaria medicinal resources
      • Abstract
      • 4.1 Introduction
      • 4.2 Chemical components and bioactivity
      • 4.3 Chemotaxonomy
      • 4.4 Molecular taxonomy, molecular phylogeny, and genomics
      • 4.5 Conclusions
    • 5: Phytochemical and biological research of Chelidonieae pharmaceutical resources
      • Abstract
      • 5.1 Introduction
      • 5.2 Alkaloids
      • 5.3 Pharmacology and therapeutic use of alkaloids
      • 5.4 Pharmacology and therapeutic use of Chelidonieae extracts
      • 5.5 Toxicity
      • 5.6 Other compounds
      • 5.7 Chemotaxonomy
      • 5.8 Molecular phylogeny and omics
      • 5.9 Conclusions
    • 6: Phytochemical and biological research of Papaver pharmaceutical resources
      • Abstract
      • 6.1 Introduction
      • 6.2 Chemical constituents
      • 6.3 Pharmacology and therapeutic use
      • 6.4 Molecular biology, phylogeny, and omics
      • 6.5 Conclusions
    • 7: Chemical and biological studies of Aconitum pharmaceutical resources
      • Abstract
      • 7.1 Introduction
      • 7.2 Diterpenoid alkaloids
      • 7.3 Pharmacology and toxicology of Aconitum alkaloids and extracts
      • 7.4 Polysaccharide
      • 7.5 Other compounds
      • 7.6 Chemotaxonomy
      • 7.7 Molecular phylogeny and genomics
      • 7.8 Conclusions
    • 8: Chemical and biological studies of Cimicifugeae pharmaceutical resources
      • Abstract
      • 8.1 Introduction
      • 8.2 Triterpenoid saponins
      • 8.3 Bioactivities and adverse effects of saponins and extracts from Cimicifugeae
      • 8.4 Bioactivity of other compounds
      • 8.5 Chemotaxonomy and authentication
      • 8.6 Molecular phylogeny and genomics
      • 8.7 Conclusion
    • 9: Chemical and biological research of Clematis medicinal resources
      • Abstract
      • 9.1 Introduction
      • 9.2 Chemical components
      • 9.3 Bioactivity and therapeutic use
      • 9.4 Chemotaxonomy
      • 9.5 Molecular taxonomy and molecular phylogeny
      • 9.6 Conclusions
    • 10: Potentilla and Rubus medicinal plants: potential non-Camellia tea resources
      • Abstract
      • 10.1 Introduction
      • 10.2 Chemical components
      • 10.3 Bioactivities
      • 10.4 Molecular pharmacognosy
      • 10.5 Proteomics
      • 10.6 Metabolomics
      • 10.7 Conclusions
    • 11: Phytochemical and biological research of Cannabis pharmaceutical resources
      • Abstract
      • 11.1 Introduction
      • 11.2 Cannabinoids
      • 11.3 Pharmacology and therapeutic use of cannabinoids
      • 11.4 Toxicity and safety
      • 11.5 Other compounds
      • 11.6 Chemotaxonomy
      • 11.7 Molecular biology, phylogeny, and omics
      • 11.8 Conclusions
    • 12: Phytochemical and biological research of Polygoneae medicinal resources
      • Abstract
      • 12.1 Introduction
      • 12.2 Chemical components
      • 12.3 Bioactivities and therapeutic uses
      • 12.4 Molecular biology and genomics
      • 12.5 Phylogeny
      • 12.6 Conclusion
    • 13: Phytochemistry and biology of Ilex pharmaceutical resources
      • Abstract
      • 13.1 Introduction
      • 13.2 Chemical components and biological activities
      • 13.3 Pharmacology of Ilex tea and extracts
      • 13.4 Toxicity and safety
      • 13.5 Chemotaxonomy
      • 13.6 Molecular taxonomy, molecular phylogeny, and genomics
      • 13.7 Conclusions
    • 14: Phytochemical and biological research of Salvia medicinal resources
      • Abstract
      • 14.1 Introduction
      • 14.2 Chemical components
      • 14.3 Pharmacology and therapeutic use
      • 14.4 Molecular phylogeny and genomics
      • 14.5 Chemotaxonomy and metabolomics
      • 14.6 Conclusions
    • 15: Phytochemical and biological research of Panax medicinal resources
      • Abstract
      • 15.1 Introduction
      • 15.2 Chemical components
      • 15.3 Pharmacology and therapeutic use
      • 15.4 Molecular phylogeny and genomics
      • 15.5 Metabolomics
      • 15.6 Conclusions
    • Index

Product details

  • No. of pages: 694
  • Language: English
  • Copyright: © Woodhead Publishing 2015
  • Published: June 25, 2015
  • Imprint: Woodhead Publishing
  • eBook ISBN: 9780081001035
  • Hardcover ISBN: 9780081000854

About the Authors

Hao Da

Da-Cheng Hao is Professor and Primary Investigator at the School of Environment and Chemical Engineering and the Biotechnology Institute, at Dalian Jiaotong University, in Dalian, China. He has published widely in the fields of medicinal plant and phytomedicine, and is the author of Medicinal Plants: Chemistry, Biology and Omics and Medicinal Plants: Biodiversity, Chemodiversity and Pharmacotherapy (Academic Press, 2018).

Affiliations and Expertise

Professor and Primary Investigator, School of Environment and Chemical Engineering and the Biotechnology Institute, Dalian Jiaotong University, Dalian, China

Xiao Jie Gu

Dr. Xiao Jie Gu is a Lecturer at the School of Environment and Chemical Engineering, based at the Biotechnology Institute, Dalian Jiaotong University, Dalian, P.R China.

Affiliations and Expertise

Lecturer, School of Environment and Chemical Engineering, Biotechnology Institute, Dalian Jiaotong University, Dalian, P.R China.

Pei Gen Xiao

Professor Pei Gen Xiao is an Academician of Chinese Academy of Engineering and the head of Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, based at IMPLAD, CAMS, Beijing, P. R China.

Affiliations and Expertise

Academician at the Chinese Academy of Engineering and Head of the Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, IMPLAD, CAMS, Beijing, P. R China