Medical Biochemistry

Medical Biochemistry

6th Edition - June 30, 2022

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  • Editors: John Baynes, Marek Dominiczak
  • Paperback ISBN: 9780323834506

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Description

Written by carefully selected global experts, practicing physicians, and educators in the various sub-disciplines of biochemistry, Medical Biochemistry, 6th Edition, offers a unique combination of research and clinical practice tailored to today's integrated courses. Covering clinically relevant topics in greater detail than other texts, this outstanding resource provides a strong overview of traditional areas in medical biochemistry along with state-of-the-art coverage of today’s latest developments. You’ll learn basic science concepts alongside clinical cases that describe patients likely to be encountered in clinical training, as well as how to use laboratory tests to diagnose and monitor the most important conditions. Thorough yet accessible, this clinically focused text is useful from medical school to clinical practice.   

Table of Contents

  •  

    Introduction

    1-Introduction

    II Molecules and cells

    2 Amino Acids and Proteins

    3– Carbohydrates and Lipids

    4- Cells, Membranes and Transport.

    III. Metabolism

    5- Hemoglobin and oxygen transport.

    6- Catalytic Proteins - Enzymes

    7- Coenzymes Vitamins and Minerals

    8- Bioenergetics and Oxidative Metabolism

    9- Anaerobic metabolism of glucose carbohydrates in the red blood cell

    10-The Tricarboxylic Acid Cycle

    11-Oxidative Metabolism of Lipids in Liver and Muscle

    12- Biosynthesis and Storage of Carbohydrates in Liver and Muscle: Glycogen metabolism and gluconeogenesis

    13- Biosynthesis and Storage of Fatty Acids

    14-"Metabolism of cholesterol and steroids".

    15- Biosynthesis and Degradation of Amino Acids

    16- Biosynthesis and Degradation of Nucleotides.

    17- Complex Carbohydrates: Glycoproteins.

    18– Complex Lipids

    19-The Extracellular Matrix.

    IV Molecular basis of inheritance

    20- Deoxyribonucleic Acid.

    21- Ribonucleic Acid.

    22– Protein Synthesis and Turnover.

    23– Regulation of Gene Expression: Basic Mechanisms

    24- Fundamentals of recombinant DNA technology, molecular hybridisation and cloning

    25- Genomics, Proteomics and Metabolomics.

    V Signalling and growth

    26- Membrane Receptors and Signal Transduction

    27- Neurotransmitters.

    28- Biochemical Endocrinology.

    29- Cellular Homeostasis: Cell Growth and Cancer.

    30- Aging

     

    VI. Fuels Nutrients and Minerals

    31- Digestion and Absorption of Nutrients: The Gastrointestinal Tract.

    32– Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus.

    33– Nutrients and diets, malnutrition and obesity

    34- Lipoprotein Metabolism and Atherogenesis.

    VII. Specialized Tissues and Their Function.

    35- The Role of Liver in Metabolism.

    36- Kidney: Water and Electrolytes Homeostasis

    37- Lung and the Regulation of Hydrogen Ion Concentration (Acid-Base Balance)

    38- Energy Metabolism and Contraction Exercise

    39– Bone Metabolism and Calcium Homeostasis.

    40- Neurochemistry

     

    VIII. Blood and immunity. Clinical biochemistry.

    41- Blood and Plasma Proteins.

    42- Haemostasis and Thrombosis.

    43- Oxidative stress and inflammation.

    44-The Immune Response: Innate and adaptive immunity.

    Appendix - selected clinical laboratory reference ranges.

    Index

Product details

  • No. of pages: 744
  • Language: English
  • Copyright: © Elsevier 2022
  • Published: June 30, 2022
  • Imprint: Elsevier
  • Paperback ISBN: 9780323834506

About the Editors

John Baynes

Affiliations and Expertise

Carolina Distinguished Professor Emeritus; Department of Pharmacology, Physiology and Neuroscience; University of South Carolina School of Medicine; Columbia, South Carolina

Marek Dominiczak

Affiliations and Expertise

Honorary Professor of Clinical Biochemistry and Medical Humanities, University of Glasgow; Consultant Biochemist, NHS Greater Glasgow and Clyde, Glasgow, UK

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