Medical Biochemistry – Indonesian 5th edition - 1st Edition - ISBN: 9789814666794

Medical Biochemistry – Indonesian 5th edition

1st Edition

Authors: John W. Baynes Marek Dominiczak
Editors: Septalia Inawati Wanandi Sri Widia A Jusman
Paperback ISBN: 9789814666794
Imprint: Elsevier (Singapore) Pte Ltd
Published Date: 6th May 2021

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Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions.

Key Features

Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the '-omics'. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine.

Table of Contents

SECTION 1 Introduction

1 Introduction

SECTION 2 Molecules and Cells

2 Amino Acids and Proteins

3 Carbohydrates and Lipids

4 (6) Enzymes and ligand-protein interactions

5 (4) Membranes and Transport

6 (17) Complex Carbohydrates: Glycoproteins

7 (18) Complex Lipids

8 (19) The Extracellular Matrix

SECTION 3 Molecular Basis of Inheritance

9 (20) Deoxyribonucleic Acid

10 (21) Ribonucleic Acid

11 (22) Protein Synthesis and Turnover

12 (23) Regulation of Gene Expression: Basic Mechanisms

13 (24) Genomics, Proteomics, and Metabolomics

SECTION 4 Signaling and Growth

14 (25) Membrane Receptors and Signal Transduction

15 (26) Neurotransmitters

16 (27) Biochemical Endocrinology

17 (28) Cellular Homeostasis: Cell Growth and Cancer

18 (29) Aging

SECTION 5 Fuels, Nutrients, Minerals and Metabolism

19 (5) Oxygen Transport

20 (8) Bioenergetics and Oxidative Metabolism

21 (10) Integrated Metabolism: The Tricarboxylic Acid Cycle

22 (30) Digestion and Absorption of Nutrients: The Gastrointestinal Tract

23 (9) Anaerobic Metabolism of Carbohydrates in the Red Blood Cell

24 (12) Biosynthesis and Storage of Carbohydrate in Liver and Muscle

25 (31) Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus

26 (11) Oxidative Metabolism of Lipids in Liver and Muscle

27 (13) Biosynthesis and Storage of Fatty Acids

28 (14) Biosynthesis of Cholesterol and Steroids

29 (33) Lipoprotein Metabolism and Atherogenesis

30 (15) Biosynthesis and Degradation of Amino Acids

31 (16) Biosynthesis and Degradation of Nucleotides

32 Xenobiotic metabolism

33 (42) Oxidative Stress and Inflammation

34 (7) Vitamins and Minerals

SECTION 6 Specialized Tissues and Their Function

35 (34) Role of the Liver in Metabolism

36 (35) Water and Electrolytes Homeostasis

37 (36) Acid–Base Balance: The Lung and the Regulation of Hydrogen Ion Concentration

38 (37) Muscle: Energy Metabolism, Contraction, and Exercise

39 (38) Bone Metabolism and Calcium Homeostasis

40 (39) Neurochemistry

41 (40) Blood and Plasma Proteins

42 (41) Hemostasis and Thrombosis

Appendix 1: Selected Clinical Laboratory Reference Ranges

Appendix 2: More Clinical Cases



© Elsevier (Singapore) Pte Ltd 2021
6th May 2021
Elsevier (Singapore) Pte Ltd
Paperback ISBN:

About the Authors

John W. Baynes

Marek Dominiczak

Affiliations and Expertise

Honorary Professor of Clinical Biochemistry and Medical Humanities, University of Glasgow; Consultant Biochemist, NHS Greater Glasgow and Clyde, Glasgow, UK

About the Editors

Septalia Inawati Wanandi

Sri Widia A Jusman