Mechanisms of Regeneration, Volume 108

1st Edition

Serial Volume Editors: Brigitte Galliot
Hardcover ISBN: 9780123914989
eBook ISBN: 9780123944108
Imprint: Academic Press
Published Date: 28th February 2014
Page Count: 368
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Table of Contents

  • Contributors
  • Preface
  • Chapter One: Genetic and Epigenetic Controls of Plant Regeneration
    • Abstract
    • 1 Introduction
    • 2 Types of Regeneration in Higher Plants
    • 3 Tissue Regeneration
    • 4 De novo Organogenesis
    • 5 Somatic Embryogenesis
    • 6 Wound Signal in Plant Regeneration
    • 7 Regeneration in Moss
    • 8 Concluding Remarks and Perspectives
    • Acknowledgments

  • Chapter Two: The Hormonal Control of Regeneration in Plants
    • Abstract
    • 1 Introduction
    • 2 Spatiotemporal Patterns of Hormonal Response are Critical to De novo Regeneration
    • 3 Hormonal Biosynthesis Contributes to the Distribution of the Hormonal Response and De novo Regeneration
    • 4 Hormonal Signaling in De novo Plant Regeneration
    • 5 Hormone Interactions During Plant Regeneration
    • 6 Concluding Remarks and Perspectives
    • Acknowledgments

  • Chapter Three: Histone Modifications and Regeneration in the Planarian Schmidtea mediterranea
    • Abstract
    • 1 Introduction
    • 2 Histone Families and Variants in S. mediterranea
    • 3 A Survey of Histone Modifications in S. mediterranea
    • 4 Distribution of Acetylation Marks in Planarian Cells
    • 5 Epigenetic Modifying Enzymes in Planarians
    • 6 Histone Modifications, Stem Cells, and Cell Lineages
    • 7 Conclusions
    • Acknowledgments

  • Chapter Four: Control of Growth During Regeneration
    • Abstract
    • 1 Cells Participating in Regenerative Growth
    • 2 Recognizing Tissue Damage to Initiate Regeneration
    • 3 Regenerative Growth is Controlled by Signaling Networks
    • 4 Control of Regenerative Growth by Organ Patterning
    • 5 Suppression of Regenerative Growth
    • 6 Conclusion
    • Acknowledgments
    • </


This new volume of Current Topics in Developmental Biology covers the area of mechanisms in regeneration. With an international board of authors, it provides a comprehensive set of reviews covering such topics as control of growth during regeneration, skeletal muscle degeneration and regeneration in mammals and flies, and suppression of regeneration in mammals.

Key Features

  • Covers the area of mechanisms in regeneration
  • International board of authors
  • Provides a comprehensive set of reviews


Researchers in cell, developmental, and molecular biology; genetics


No. of pages:
© Academic Press 2014
Academic Press
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Hardcover ISBN:

About the Serial Volume Editors

Brigitte Galliot Serial Volume Editor

My scientific interest has always been focused on the different aspects of development, from the first morphogenetic stages to the complex mechanisms of neurogenesis and regeneration. This led me to study medicine (Paris, France) and to start a medical career in the field of embryology and pediatrics. I however soon realized that my scientific interests could only be satisfied after a more complete formation in basic biological and biochemical sciences. My nomination as MD resident in Strasbourg hospitals gave me the unexpected opportunity to join one of the leading French laboratories in the field of molecular biology (Pierre CHAMBON) and to acquire a formation as a molecular biologist. After a Master in the biochemistry of transcription I started a PhD work in the field of molecular genetics of development, where I characterized transcription factors (Hox genes) involved in the establishment of the vertebrate body plan, using the mouse as a model system. Thereafter I joined the laboratory of Chica SCHALLER in Heidelberg (Germany) for a post-doctoral stage to study the molecular developmental biology of Hydra. This freshwater cnidarian polyp, which displays a rather simple apical to basal organization but differentiates a sophisticated nervous system and is capable of budding and regeneration, is a potent model system to study the biology of stem cells, the mechanisms of regeneration. The discovery since 1984 that all animals share a similar complement of genes convinced me of the paradigmatic value of this little animal to understand some fundamental processes that support cell and developmental plasticity in metazoans. I started to settle a molecular biology approach, which led in the cloning of several transcription factors, homeobox- and bZIP-containing genes, unexpectedly similar to their vertebrate counterparts. Moreover their regulation during regeneration confirmed our hope that developmental pathways had been conserved throughout evolution. Since 1993, in

Affiliations and Expertise

Department of Genetics and Evolution, University of Geneva, Switzerland