Mechanisms and Pathways of Heterotrimeric G Protein Signaling, Volume 74

1st Edition

Authors: Stephen Sprang
Hardcover ISBN: 9780120342884
eBook ISBN: 9780080552699
Imprint: Academic Press
Published Date: 1st October 2007
Page Count: 290
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Table of Contents

1. Structural basis of effector regulation and signal termination in heterotrimeric GƒÑƒnƒnproteins Stephen R. Sprang, Zhe Chen and Xinlin Du 2. How do receptors activate G proteins? William M. Oldham and Heidi E. Hamm 3. Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads Tione Buranda, Anna Waller, Yang Wu, Peter C. Simons, Sean Biggs, Eric R. Prossnitz and Larry A. Sklar 4. Activation of G protein coupled receptors Xavier Deupi and Brian Kobilka 5. Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells Martin J. Lohse, Carsten Hoffmann, Viacheslav O. Nikolaev, Jean-Pierre Vilardaga and Moritz Bunemann 6. Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins Paul C. Sternweis, Angela M. Carter, Zhe Chen, Shahab M. Danesh, Ying-Fan Hsiung, and William D. Singe

Description

This volume in the Advances in Protein Chemistry series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the structural basis of effector regulation and signal termination in heterotrimeric GƒÑƒnƒnproteins; How do receptors activate G proteins; Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads; Activation of G protein coupled receptors; Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells; Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins.

Readership

Researchers in biochemistry, molecular biology, cell biology, and biophysics.


Details

No. of pages:
290
Language:
English
Copyright:
© Academic Press 2007
Published:
Imprint:
Academic Press
eBook ISBN:
9780080552699
Hardcover ISBN:
9780120342884

Reviews

This volume in the Advances in Protein Chemistry series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the structural basis of effector regulation and signal termination in heterotrimeric GƒÑƒnƒnproteins; How do receptors activate G proteins; Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads; Activation of G protein coupled receptors; Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells; Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins.


About the Authors

Stephen Sprang Author

Affiliations and Expertise

University of Texas Southwestern Medical Center, Dallas, Texas, USA