Description

This volume in the Advances in Protein Chemistry series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the structural basis of effector regulation and signal termination in heterotrimeric GƒÑƒnƒnproteins; How do receptors activate G proteins; Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads; Activation of G protein coupled receptors; Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells; Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins.

Readership

Researchers in biochemistry, molecular biology, cell biology, and biophysics.

Table of Contents

1. Structural basis of effector regulation and signal termination in heterotrimeric GƒÑƒnƒnproteins Stephen R. Sprang, Zhe Chen and Xinlin Du 2. How do receptors activate G proteins? William M. Oldham and Heidi E. Hamm 3. Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads Tione Buranda, Anna Waller, Yang Wu, Peter C. Simons, Sean Biggs, Eric R. Prossnitz and Larry A. Sklar 4. Activation of G protein coupled receptors Xavier Deupi and Brian Kobilka 5. Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells Martin J. Lohse, Carsten Hoffmann, Viacheslav O. Nikolaev, Jean-Pierre Vilardaga and Moritz Bunemann 6. Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins Paul C. Sternweis, Angela M. Carter, Zhe Chen, Shahab M. Danesh, Ying-Fan Hsiung, and William D. Singe

Details

No. of pages:
290
Language:
English
Copyright:
© 2007
Published:
Imprint:
Academic Press
Print ISBN:
9780120342884
Electronic ISBN:
9780080552699