Mathematical and Computational Methods in Physiology

Mathematical and Computational Methods in Physiology

Satellite Symposium of the 28th International Congress of Physiological Sciences, Budapest, Hungary, 1980

1st Edition - January 1, 1981

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  • Editors: L. Fedina, B. Kanyár, B. Kocsis
  • eBook ISBN: 9781483190228

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Mathematical and Computational Methods in Physiology discusses the importance of quantitative description of physiological phenomena and for quantitative comparison of experimental data. An article explains the homeostasis of the body with a focus on the controlling aspects. This section evaluates the concepts of modern physiology and biocybernetics. The canal-ocular reflex and the otolith-ocular reflex in man stimulates eye rotations compensatory for head angular and linear displacements. The book enumerates some modelling and simulation to observe the visual-vestibular interaction during angular and linear body acceleration. A section on the determination of cardiovascular control is given. The text reviews the mathematical models of the biological age of the rat. A numerical simulation of water transport in epithelial junctions is explained comprehensively. A chapter analyzing the computer simulation of drug-receptor interaction is presented. The book will provide useful information to zoologists, doctors, ophthalmologists, students and researchers in the field of medicine.

Table of Contents

  • Preface


    Modeling and Simulation of Physiological Systems

    Homeostasis of the Body: Control Aspects

    Visual—Vestibular Interaction During Angular and Linear Body Acceleration: Modeling and Simulation

    A Volterra-Like Dissection of Dynamic Test Responses for the Identification of Cardiovascular Control

    Modeling of the CO2 Rebreathing Cardiac Output Measurement

    Problems of Applying Biomechanical Models in Determining Cardiovascular System's Reliability during a Cosmic Mission

    A Mathematical Model of Mechanical Properties of the Rat's Aorta

    Mathematical Models of the Biological Age of The Rat

    Numerical Simulation of Water Transport in Epithelial Junctions

    Analytic Properties And Identifiability Problems of Compartmental Models with Time-Lags

    The Modeling of Tagged Particles Migration in Physiological Systems

    Criteria for Computer Simulation of Drug—Receptor Interaction

    A New Stochastic Approach to Compartments with Combined Cross-Section and Time-Series Data

    Stationary Distributions in Stochastic Kinetics

    Oscillatory Phenomena at the Synapse

    Spatial Growth of Tumors. A Simulation Study

    Some Model Applications of the Fuzzy Sets Theory in Decision-Making

    Complex Method for the Determination of the Physiological Parameters of Bacterium Phage Systems

    Concluding Remarks on Modeling and Simulation of Physiological Systems

    Design of Experiments and Estimation of Parameters

    On Structural Equivalence of Compartmental Models

    Design of Tracer Kinetic Experiments for Precise Parameter Estimation

    D-Optimal Design in Case of Exponential and Sigmoid Response Functions

    Fourier Transform Method for Decomposition of Ca Flux Data on Skeletal Muscle

    Kinetic Models: Uncertain Identification But Some Robust Parameters

    A Second Order Method for the Parameter Estimation of Linear Compartmental Models

    Computational Aspects of Parameter Estimation in Case of Differential Equation Systems

    Parameter Estimation of the Radiocardiogram Using Compartmental Models with Pipes

    A Formal Dynamic Model of The Development of Purkinje Dendritic Spines

    Parameter Estimation in the Conscious Dog's Cardiovascular System

    Concluding Remarks on Design of Experiments and Estimation of Parameters

    Computers in Physiological Laboratory; Analysis of Analog Biosignals

    Analog Computer Model for Studying Coronary Circulation

    Measurement of Left Ventricular Pressure-Volume-Loops by Means of a Mobile Gamma Camera Computer System

    Automatized Data Acquisition and Processing by a Microcomputerin a Neuroendocrinology Laboratory

    Microcomputer-Aided Point-Process Analysis of Epileptic Unit Activity

    Testing The Stability of Biological Oscillations

    Missing Data Problems in Estimating The Parameters of Biological Oscillations

    A Principal Component Model of the Time Series of the Broad-Band EEG Frequency Spectra and of the EEG Spectral Power Densities

    Spectral Analysis of Nonstationary EEG

    Comparison of Vegetative Reactions Using Frequency Domain Data Reduction

    Computer Analysis of Gastric Movements Recorded By Strain Gage Technique in Restrained Rats

    Concluding Remarks on Analysis of Analog Biosignals


Product details

  • No. of pages: 352
  • Language: English
  • Copyright: © Pergamon 1981
  • Published: January 1, 1981
  • Imprint: Pergamon
  • eBook ISBN: 9781483190228

About the Editors

L. Fedina

B. Kanyár

B. Kocsis

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