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Malaria: Volume 3, Immunology and Immunization is a collection of papers dealing with malaria parasites, the methods for measuring the immunological response to plasmodia, and the vertebrates host's immune response to plasmodia. Some papers discuss immunization against sporozoites, against the exoerythrocytic stages of malaria parasites, against asexual blood-inhabiting stages of plasmodia, as well as gamete immunization in malaria. One paper describes various separation methods to isolate malaria parasites and their constituents. Another paper discusses in detail the theory and practice of methods used in measuring antibody responses which occur during plasmodial infections, including the antibody response against sporozoites, exoerythrocytic forms, and in the different blood stages. Another paper explains the vertebrate host's immune response to plasmodial infection as a homeostatic physiological response changing along with the progression of the disease. The changes in the dynamic cellular cascade are different as the disease progresses causing death, than when these lead to recovery. Another paper enumerates the parameters which determine malarial infectiousness from one individual to another such as the time of onset, duration, intensity of the blood infections, as well as the maturity, longevity, and rate of production of gametocytes. Pharmacologists, general medical practitioners, investigators, and laboratory technicians involved in malarial research will find the collection very useful.
List of Contributors
Contents of Volumes 1 and 2
Contents of Babesiosis
1 The Isolation of Malaria Parasites and Their Constituents
II. Isolation of Plasmodia and Their Constituents
2 Methods for Measuring the Immunological Response to Plasmodia
II. The Antibody Response against Sporozoites
III. The Antibody Response against Exoerythrocytic Forms
IV. The Antibody Response to Blood Stages
3 The Vertebrate Host’s Immune Response to Plasmodia
II. The Immune Response against Plasmodia
III. Summary and Hypothesis: Probable Mechanisms of Immunity to Plasmodia
4 Immunization against Sporozoites
II. Immunization of Rodents against Sporozoite-Induced Malaria
III. Immunization of Simian Hosts against Sporozoite-Induced Malaria
IV. Immunization of Humans against Sporozoite-Induced Malaria
5 Immunization against Exoerythrocytic Stages of Malaria Parasites
II. Immune Responsiveness to Exoerythrocytic Stages
6 Immunization against Asexual Blood-Inhabiting Stages of Plasmodia
II. Immunization against Bird Malaria Parasites
III. Immunization against Rodent Malaria Parasites
IV. Immunization against Simian Malaria Parasites
V. Immunization against Human Malaria Parasites
VI. Summary and Conclusion
7 Infectiousness and Gamete Immunization in Malaria
II. Avian Malaria (Plasmodium gallinaceum)
III. Rodent Malaria(Plasmodium yoelii)
IV. Simian Malaria
V. Human Malaria
Appendix 1 Prospects for Development of Vaccines against Plasmodium falciparum Infection
II. Experimental Immunization against Plasmodium falciparum Blood Stages
III. Immunization of Humans against Sporozoite-Induced Malaria
IV. Prerequisites for Vaccines for Human Use
Appendix 2 The Role of Vaccination in the Strategy of Malaria Control
Appendix 3 Prospects for Malaria Blood Stage Vaccine
Appendix 4 Manufacturing Aspects of Antiplasmodial Vaccine Production
Appendix 5 The Agency of International Development Program for Malaria Vaccine Research and Development
Appendix 6 The Great Neglected Diseases of Mankind
- No. of pages:
- © Academic Press 1980
- 28th January 1980
- Academic Press
- eBook ISBN:
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