Malaria - 1st Edition - ISBN: 9780124261037, 9781483257471

Malaria

1st Edition

Immunology and Immunization

Editors: Julius P. Kreier
eBook ISBN: 9781483257471
Imprint: Academic Press
Published Date: 28th January 1980
Page Count: 364
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Description

Malaria: Volume 3, Immunology and Immunization is a collection of papers dealing with malaria parasites, the methods for measuring the immunological response to plasmodia, and the vertebrates host's immune response to plasmodia. Some papers discuss immunization against sporozoites, against the exoerythrocytic stages of malaria parasites, against asexual blood-inhabiting stages of plasmodia, as well as gamete immunization in malaria. One paper describes various separation methods to isolate malaria parasites and their constituents. Another paper discusses in detail the theory and practice of methods used in measuring antibody responses which occur during plasmodial infections, including the antibody response against sporozoites, exoerythrocytic forms, and in the different blood stages. Another paper explains the vertebrate host's immune response to plasmodial infection as a homeostatic physiological response changing along with the progression of the disease. The changes in the dynamic cellular cascade are different as the disease progresses causing death, than when these lead to recovery. Another paper enumerates the parameters which determine malarial infectiousness from one individual to another such as the time of onset, duration, intensity of the blood infections, as well as the maturity, longevity, and rate of production of gametocytes. Pharmacologists, general medical practitioners, investigators, and laboratory technicians involved in malarial research will find the collection very useful.

Table of Contents


List of Contributors


Preface


Contents of Volumes 1 and 2


Contents of Babesiosis


1 The Isolation of Malaria Parasites and Their Constituents


I. Introduction


II. Isolation of Plasmodia and Their Constituents


III. Conclusions


References


2 Methods for Measuring the Immunological Response to Plasmodia


I. Introduction


II. The Antibody Response against Sporozoites


III. The Antibody Response against Exoerythrocytic Forms


IV. The Antibody Response to Blood Stages


Reference


3 The Vertebrate Host’s Immune Response to Plasmodia


I. Introduction


II. The Immune Response against Plasmodia


III. Summary and Hypothesis: Probable Mechanisms of Immunity to Plasmodia


References


4 Immunization against Sporozoites


I. Introduction


II. Immunization of Rodents against Sporozoite-Induced Malaria


III. Immunization of Simian Hosts against Sporozoite-Induced Malaria


IV. Immunization of Humans against Sporozoite-Induced Malaria


V. Conclusions


VI. Perspectives


References


5 Immunization against Exoerythrocytic Stages of Malaria Parasites


I. Introduction


II. Immune Responsiveness to Exoerythrocytic Stages


III. Discussion


References


6 Immunization against Asexual Blood-Inhabiting Stages of Plasmodia


I. Introduction


II. Immunization against Bird Malaria Parasites


III. Immunization against Rodent Malaria Parasites


IV. Immunization against Simian Malaria Parasites


V. Immunization against Human Malaria Parasites


VI. Summary and Conclusion


References


7 Infectiousness and Gamete Immunizat

Details

No. of pages:
364
Language:
English
Copyright:
© Academic Press 1980
Published:
Imprint:
Academic Press
eBook ISBN:
9781483257471

About the Editor

Julius P. Kreier

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