- Electronic ISBN 9780124016972
- Print ISBN 9780124016880
Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations.
Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective.
Neuroscience researchers and clinicians (neurologists, radiologists, psychiatrists) using MR imaging
Section 1: How MRS is Acquired
Section 2: Biochemistry—What Underlies the Signal?
Section 3: Applications of Proton MRS
Section 4: Applications of Non-Proton MRS
Section 1: Technical Aspects—How MRS is Acquired
Chapter 1.1. Basis of Magnetic Resonance
Chapter 1.2. Localized Single-Voxel Magnetic Resonance Spectroscopy, Water Suppression, and Novel Approaches for Ultrashort Echo-Time Measurements
Instrumental Impacts on Volume Definition
Factors Affecting Spectral Quality
Basic Localization 1H Mrs Methods
Chapter 1.3. Technical Considerations for Multivoxel Approaches and Magnetic Resonance Spectroscopic Imaging
Fast Gradient-Encoding Methods
Encoding Based on Prior Knowledge
Chapter 1.4. Spectral Editing and 2D NMR
In Vivo GABA Editing
2D NMR Spectroscopy
Chapter 1.5. Spectral Quantification and Pitfalls in Interpreting Magnetic Resonance Spectroscopic Data: What To Look Out For
Introduction: A Simple Example of Spectral Quantitation
Measuring Peak Intensity
Software Packages for Spectral Quantification
Signal Referencing and Absolute Quantification
Section 2: Biochemistry — What Underlies the Signal?
Chapter 2.1. N-Acetylaspartate and N-Acetylaspartylglutamate in Ce
"Specialists in the neurosciences and in Magnetic Resonance Specctroscopy technology present a reference of the imaging technology for neurologists, psychiatrists, radiologists, and neuroscientists…The areas covered are technical aspects - how MRS is acquired, biochemistry - what underlies the signal, and applications of proton and non-proton MRS."--ProtoView.com, April 2014