Description

Cell separation is at the core of current methods in experimental biology and medicine. Its importance is illustrated by the large number of physical and biochemical principles that have been evaluated for application to cell separation. The development of cell separation methods is driven by the needs of biological and medical research, and the ever-increasing demands for sensitivity, selectivity, yield, timeliness and economy of the process. The interdisciplinary nature of research in this area and the volume of information available in research publications and conferences necessitates a basic description of the fundamental processes involved in magnetic cell separation that may help the user in navigating this wealth of information available online and in scientific publications. This book will appeal to researchers in many areas utilizing this technique, including those working in cell biology, clinical research, inorganic chemistry, biochemistry, chemical engineering, materials science, physics and electrical engineering.

Key Features

  • Provides examples of how to calculate the volume magnetic susceptibility, a fundamental quantity for calculating the magnetic force acting on a cell, from various types of magnetic susceptibilities available in literature
  • Introduces the elements of magnetostatics as they apply to cell magnetization and the magnetization of magnetic micro- and nano- particles used for cell separation
  • Describes the parameters used to determine cell magnetophoresis

Readership

Cell biologists, biochemists, inorganic chemists, chemical engineers, material scientists, physicists and electrical engineers

Table of Contents

Magnetic Susceptibility
Magnetic Formulary
Maxwell Stress
Basic Magnetic Field Configurations
Magnetophoresis
Synthesis and Characterization of Nano and Micron-Sized Iron Oxide and Iron. Particles for Biomedical Applications
The Biocompatibility and Toxicity of Magnetic Particles
Analytical Magnetic Techniques in Biology
Preparative Applications of Magnetic Separation in Biology and Medicine
Commercial Magnetic Cell Separation Instruments and Reagents
Worked Examples of Cell Sample Preparation and Magnetic Separation Procedures
New Challenges and Opportunities

Details

No. of pages:
486
Language:
English
Copyright:
© 2008
Published:
Imprint:
Elsevier Science
eBook ISBN:
9780080553504
Print ISBN:
9780444527547

About the series-volume-editors

Maciej Zborowski

Affiliations and Expertise

Lerner Research Institute, Cleveland Clinic, Cleveland, OH, U.S.A.

Jeffrey J. Chalmers

Affiliations and Expertise

The Ohio State University, Columbus, OH, U.S.A.