Magnetic Cell Separation

Magnetic Cell Separation

1st Edition - September 28, 2007

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  • Editors: Maciej Zborowski, Jeffrey J. Chalmers
  • Hardcover ISBN: 9780444527547
  • eBook ISBN: 9780080553504

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Cell separation is at the core of current methods in experimental biology and medicine. Its importance is illustrated by the large number of physical and biochemical principles that have been evaluated for application to cell separation. The development of cell separation methods is driven by the needs of biological and medical research, and the ever-increasing demands for sensitivity, selectivity, yield, timeliness and economy of the process. The interdisciplinary nature of research in this area and the volume of information available in research publications and conferences necessitates a basic description of the fundamental processes involved in magnetic cell separation that may help the user in navigating this wealth of information available online and in scientific publications. This book will appeal to researchers in many areas utilizing this technique, including those working in cell biology, clinical research, inorganic chemistry, biochemistry, chemical engineering, materials science, physics and electrical engineering.

Key Features

  • Provides examples of how to calculate the volume magnetic susceptibility, a fundamental quantity for calculating the magnetic force acting on a cell, from various types of magnetic susceptibilities available in literature
  • Introduces the elements of magnetostatics as they apply to cell magnetization and the magnetization of magnetic micro- and nano- particles used for cell separation
  • Describes the parameters used to determine cell magnetophoresis


Cell biologists, biochemists, inorganic chemists, chemical engineers, material scientists, physicists and electrical engineers

Table of Contents

  • Magnetic Susceptibility
    Magnetic Formulary
    Maxwell Stress
    Basic Magnetic Field Configurations
    Synthesis and Characterization of Nano and Micron-Sized Iron Oxide and Iron. Particles for Biomedical Applications
    The Biocompatibility and Toxicity of Magnetic Particles
    Analytical Magnetic Techniques in Biology
    Preparative Applications of Magnetic Separation in Biology and Medicine
    Commercial Magnetic Cell Separation Instruments and Reagents
    Worked Examples of Cell Sample Preparation and Magnetic Separation Procedures
    New Challenges and Opportunities

Product details

  • No. of pages: 486
  • Language: English
  • Copyright: © Elsevier Science 2007
  • Published: September 28, 2007
  • Imprint: Elsevier Science
  • Hardcover ISBN: 9780444527547
  • eBook ISBN: 9780080553504

About the Series Volume Editors

Maciej Zborowski

Affiliations and Expertise

Lerner Research Institute, Cleveland Clinic, Cleveland, OH, U.S.A.

Jeffrey J. Chalmers

Affiliations and Expertise

The Ohio State University, Columbus, OH, U.S.A.

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