Luminescent Metal Nanoclusters

Synthesis, Characterization, and Applications

1st Edition - June 28, 2022
Editors: Sabu Thomas, Kuruvilla Joseph, Saritha Appukuttan, Meegle S. Mathew
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 8 8 6 5 7 - 4
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 8 6 4 1 - 3

Luminescent Metal Nanoclusters: Synthesis, Characterization, and Applications provides a comprehensive accounting of various protocols used for the synthesis of metal nanoclust… Read more

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Luminescent Metal Nanoclusters: Synthesis, Characterization, and Applications provides a comprehensive accounting of various protocols used for the synthesis of metal nanoclusters, their characterization techniques, toxicity evaluation and various applications and future prospects. The book provides detailed experimental routes, along with mechanisms on the formation of benign metallic clusters using biomaterials and a comprehensive review regarding the preparation, properties and prospective applications of these nano clusters in various fields, including therapeutic applications. Various methods to protect nanocluster materials to increase their stability are emphasized, including the incorporation of ligands (protein, small molecule, DNA, thiols).

This book addresses a gap in the current literature by bringing together the preparation, characterization and applications of all the possible types of reported metal nanoclusters and their hybrids. It is suitable for materials scientists and engineers in academia and those working in research and development in industry. It may also be of interest to those working in the interdisciplinary nanotechnology community, such as physical chemists.

Cover image
Title page
Table of Contents
Copyright
List of contributors
About the editors
1. General introduction—luminescent metal nanoclusters
Abstract
1.1 Introduction
1.2 Overview of the chapters
1.3 Conclusion
References
2. Methods of synthesis of metal nanoclusters
Abstract
2.1 Introduction
2.2 Synthesis methods of metal nanoclusters
2.3 Summary and future prospective
Acknowledgments
References
3. Analytical tools for the characterization and quantification of metal nanoclusters
Abstract
3.1 Introduction
3.2 Morphology, size, and polydispersity characteristics
3.3 Structural information and chemical composition
3.4 Conclusion and future perspective
Acknowledgments
References
4. Mass spectrometry and metal nanoclusters
Abstract
4.1 Introduction
4.2 Brief history and important terminologies
4.3 Clusters and MS: a long-term association
4.4 MS as a tool in ligand protected metal nanoclusters
4.5 Conclusions and future perspectives
References
5. Origin of luminescence of metal nanoclusters
Abstract
5.1 Introduction
5.2 Effect of size
5.3 Effect of ligand
5.4 Effect of charge state
5.5 Role of solvent
5.6 Effect of doping
5.7 Conclusion and future perspectives
References
6. General purification methods of metal nanoclusters
Abstract
6.1 Introduction
6.2 Separation of the colloidal suspension in two fractions
6.3 Separation of the colloidal suspension in several fractions
6.4 Conclusions and future perspectives
References
7. Phosphine and thiol protected metal nanoclusters
Abstract
7.1 Introduction
7.2 Synthesis and general characteristics
7.3 Factors affecting emission
7.4 Recent developments in luminescent nanoclusters
7.5 Conclusion and future perspective
Acknowledgment
References
8. Polymer- and dendrimer-protected metal nanoclusters
Abstract
8.1 Introduction
8.2 Synthetic polymers
8.3 Dendrimer
8.4 Biopolymers: proteins and peptides
8.5 Biopolymers: DNAs
8.6 Applications
8.7 Conclusion and future perspective
Acknowledgment
References
9. DNA-protected metal nanoclusters
Abstract
9.1 Introduction
9.2 Metal–DNA interactions
9.3 Synthesis of DNA-templated metal nanoclusters
9.4 DNA sequence and structure-dependent formations of metal nanoclusters
9.5 Applications of DNA-metal nanoclusters
9.6 Conclusion and future perspectives
References
10. Peptide-protected metal nanoclusters
Abstract
10.1 Introduction
10.2 Designed peptide-protected fluorescent nanocluster: approach and applications
10.3 Tripeptide-protected fluorescent nanocluster: approach and applications
10.4 Summary and outlook
References
11. Protein and enzyme protected metal nanoclusters
Abstract
11.1 Introduction
11.2 Synthetic methods
11.3 Role of amino acids
11.4 Proteins derived from animal for stabilization of nanocluster
11.5 Protein derived from plant stabilized nanoclusters
11.6 Enzyme stabilized nanocluster
11.7 Characterization methods
11.8 Nanozymes
11.9 Application of metal nanoclusters
11.10 Conclusion and future perspectives
References
12. Alloy nanoclusters-synthesis methods and structural evaluation
Abstract
12.1 Introduction
12.2 Preparation and structures of alloy nanoclusters
12.3 Properties of alloy nanoclusters
12.4 Conclusion and perspective
Acknowledgments
Competing interest
References
13. Self-assembly of metal nanoclusters in colloid science
Abstract
13.1 Introduction
13.2 Self-assembly of metal nanoclusters
13.3 Conclusion and future perspective
References
14. Applications of metallic nanoclusters in bioimaging
Abstract
14.1 Introduction
14.2 Synthesis and biofunctionalization of metal nanoclusters
14.3 Gold nanoclusters (AuNCs)
14.4 Silver nanoclusters (AgNCs)
14.5 Copper nanoclusters (CuNCs)
14.6 Conclusion and future perspectives
References
15. Biomarker sensing using luminescent metal nanoclusters
Abstract
15.1 Introduction
15.2 Detection of cancer biomarkers
15.3 Detection of cardiovascular biomarkers
15.4 Detection of other disease-related biomarkers
15.5 Conclusion and prospects
References
16. Environmental applications of luminescent metal nanoclusters
Abstract
16.1 Introduction
16.2 pH sensing
16.3 Heavy metal ion detection
16.4 Inorganic anion detection
16.5 Nitroaromatic explosives detection
16.6 Other pollutants
16.7 Conclusion and future challenges
References
17. Therapeutic applications of metal nanoclusters
Abstract
17.1 Introduction
17.2 Potentials of metal nanoclusters in therapeutics
17.3 Monitoring ROS using fluorescent AuNCs
17.4 Protection of protein by nanoclusters from UVC radiation
17.5 Toxicity of metal nanoclusters
17.6 Conclusion and future prospects of metal nanoclusters in therapies
References
18. Stimuli-responsive metal nanoclusters for targeted drug and gene delivery and their biomedical applications
Abstract
18.1 Introduction
18.2 Stimuli-responsive nanocarriers for targeted drug delivery
18.3 Stimuli-responsive nanocarriers for various biomedical applications
18.4 Conclusions and future perspectives
References
19. Antimicrobial properties of metal nanoclusters
Abstract
19.1 Introduction
19.2 Antibacterial activity of metal nanoclusters
19.3 Design of antimicrobial metal nanoclusters
19.4 Metal nanocluster-based antibacterial hybrid
19.5 Antibacterial mechanisms
19.6 Conclusion and future perspective
References
20. Metal nanoclusters as photosensitizers
Abstract
20.1 Introduction
20.2 Photosensitizer for therapy
20.3 Photosensitization in solar cells
20.4 Conclusion and future perspective
References
21. Metal nanoclusters for catalytic applications: synthesis and characterization
Abstract
21.1 Introduction
21.2 Catalytic applications of metal nanoclusters
21.3 Conclusion and future perspectives
References
22. Metal nanoclusters for energy storage applications
Abstract
22.1 Introduction
22.2 Solar cells
22.3 Metal nanoclusters for battery and supercapacitors application
22.4 Conclusion and perspectives
Acknowledgments
References
23. Bioavailability, biodistribution, and toxicity of fluorescent metal nanoclusters
Abstract
23.1 Introduction
23.2 Metallic nanoclusters’ bioavailability
23.3 Metallic nanoclusters’ biodistribution
23.4 Metallic nanoclusters’ toxicity
23.5 Conclusion and future perspective
References
24. Luminescent Metal Nanoclusters: Summary and future outlook
Abstract
Summary and future outlook
Index

Sabu Thomas

Dr. Thomas is the Vice-Chancellor and a Professor of Polymer Science and Engineering at Mahatma Gandhi University, India. Additionally, he serves as the Director of the School of Energy Materials at the same institution. Dr. Thomas is internationally recognized for his contributions to polymer science and engineering, covering polymer nanocomposites, elastomers, polymer blends, interpenetrating polymer networks, polymer membranes, green composites, nanocomposites, nanomedicine, and green nanotechnology. His groundbreaking inventions in polymer nanocomposites, polymer blends, green bionanotechnological, and nano-biomedical sciences have significantly contributed to the development of new materials in the automotive, space, housing, and biomedical fields. Dr. Thomas has been conferred with Honoris Causa (DSc) by the University of South Brittany, Lorient, France.

Affiliations and expertise

Vice-chancellor, Mahatma Gandhi University, India

Kuruvilla Joseph

Kuruvilla Joseph is a Professor in the Department of Chemistry at the Indian Institute of Space Science and Technology, Thiruvananthapuram, India. His research areas includes nanomaterials and nanocomposites, polymer blends and composites, synthesis of polymers from natural resources, green materials and biocomposites, aging and degradation, and development of biosensors.

Affiliations and expertise

Outstanding Professor and Dean, Department of Chemistry, Indian Institute of Space Science and Technology

Saritha Appukuttan

Dr. Saritha Appukuttan was awarded her PhD from Mahatma Gandhi University in 2012 working in the field of polymer nanocomposites. She has also been worked for two years on the development of gas barrier membranes on an ISRO (Indian Space Research Organization) project. She has published around 25 book chapters with highly reputed publishers and several research papers in high impact international journals such as Composites Part A, Composites Part B, and Materials Chemistry and Physics and has edited two books on “Fibre Reinforced Composites: Constituents, compatibility, perspectives and applications” (Elsevier) and on “Luminescent Metal Nanoclusters” (Elsevier). Currently, she is editing two more books on “Lignin and its Composites: A sustainable tool for health care and medical applications” and “Zero-Dimensional Carbon Nanostructures” to be published by RSC and Elsevier, respectively.

Affiliations and expertise

Assistant Professor, Department of Chemistry, School of Arts and Sciences, Amrita Vishwavidyapeetham, Amritapuri, Kollam, India

Meegle S. Mathew

Meegle S. Mathew is an Assistant Professor in the Department of Chemistry at Mar Athanasius College, Kothamangalam, India. Her research interests cover nano-biophotonics, optical imaging, the development of biosensors and biomedical devices using fluorescent nanoparticles, polymer nanocomposites for biomedical applications, photocatalysis, and photoreduction.

Affiliations and expertise

Assistant Professor, Department of Chemistry, Mar Athanasius College, Kothamangalam, India