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Long-Acting Drug Delivery Systems - 1st Edition - ISBN: 9780128217498

Long-Acting Drug Delivery Systems

1st Edition

Pharmaceutical, Clinical, and Regulatory Aspects

Editors: Eneko Larraneta Thakur Raghu Raj Singh Ryan Donnelly
Paperback ISBN: 9780128217498
Imprint: Woodhead Publishing
Published Date: 27th August 2021
Page Count: 365
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Table of Contents

Part 1. Introduction to long-acting and implantable drug delivery systems

1. Overview of the clinical current needs and potential applications for long-acting drug delivery systems

Part 2. Classification, material types, and design principles of long-acting drug delivery systems

2. Classification, material types and design approaches of long-acting and implantable drug delivery systems.

Part 3. Applications of long-acting drug delivery systems

3. Long-acting drug delivery systems for ocular therapies
4. Applications of long lasting and implantable drug delivery systems for cardiovascular disease treatment.
5. Implantable and long lasting drug delivery systems for cancer treatment.
6. Sexual and reproductive health long lasting drug delivery systems applications.
7. Implantable and long lasting drug delivery systems for schizophrenia treatment
8. Implantable and long-lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases
9. Long lasting drug delivery systems based on microneedles

Part 4. Safety issues and measures for long-acting drug delivery systems

10. Safety, biodegradability and biocompatibility consideration of long-acting and implantable drug delivery systems
11. Characterisation methodologies for long-acting and implantable drug delivery systems

Part 5. Industrial and regulatory aspects of long-acting drug delivery systems

12. Challenges for clinical translation of long-acting and implantable drug delivery systems. Regulatory aspects, commercial products and products under clinical evaluation


Description

Long-Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects offers a comprehensive overview of the technical, clinical, regulatory and industrial perspectives on these drug delivery systems. The book follows a sequential order, beginning with the current technical state-of-the-field and moving on to more clinical, industrial and regulatory topics. Opening chapters describe the current needs and potential applications of implantable and long-acting therapeutic approaches. The book goes on to describe established and novel long-acting systems, with a focus on the materials used to prepare these systems and their biocompatibility.

Importantly, applied topics such as scale-up manufacturing, products under clinical trials and regulatory aspects are covered, offering the reader a holistic view of this rapidly growing field.

Key Features

  • Brings together technical, clinical, regulatory and industrial perspectives for a complete overview of long acting and implantable drug delivery systems
  • Provides up-to-date coverage of established and novel long-acting and implantable drug delivery systems, both in development and actively in use
  • Appeals to a broad readership, including materials scientists, pharmaceutical scientists, biomedical engineers, clinicians and regulatory experts

Readership

Researchers in industry and academia working on drug delivery, across a broad selection of fields including pharmaceutical science, materials science and biomedical engineering. Advanced students in these areas also a potential audience for the proposed book due to the increasing importance of long acting drug delivery systems. Clinicians and regulatory experts


Details

No. of pages:
365
Language:
English
Copyright:
© Woodhead Publishing 2021
Published:
27th August 2021
Imprint:
Woodhead Publishing
Paperback ISBN:
9780128217498

Ratings and Reviews


About the Editors

Eneko Larraneta

Dr Eneko Larrañeta is a Lecturer in Pharmaceutical Sciences at the School of Pharmacy Queen’s University Belfast. He worked in different multidisciplinary first-class laboratories developing drug delivery systems. His research area falls within the interface of pharmaceutics, chemistry, engineering and biomedical sciences. During his independent career, he developed research projects for industrial partners (L’Oreal) and research councils (Wellcome Trust, Royal Society, PATH among others). To date, he has published more than 40 peer-reviewed papers in leading international journals, as well as 4 book chapters, 1 invited presentation and 11 conference abstracts, describing a range of advanced drug delivery systems, including nanoparticles and microneedles.

Affiliations and Expertise

School of Pharmacy, Queen's University Belfast, Medical Biology Centre, Belfast, UK

Thakur Raghu Raj Singh

Dr Thakur obtained his PhD in Drug Delivery from School of Pharmacy, Queens University Belfast (2009), M.Sc in Pharmaceutical Sciences from University Science Malaysia (2006) and B.Pharm from Jawaharlal Nehru Technological University, India (2002). His current research involves the fabrication and design of novel long-acting injectable and implantable drug delivery systems for treating back of the eye disorders. Dr Thakur's ocular drug delivery research has led to the formation of Re-Vana Therapeutics Ltd. He is currently acting as the CSO for Re-Vana. He is Chair for Ocular Delivery (OcD) Focus Group supported by the mission of Controlled Release Society (CRS). He has authored over 150 scientific publications, including 52 peer-reviewed research papers, 10 book chapters and 4 textbooks. He has been an invited speaker at a number of national/international meetings. He is currently Editorial Board member of the International Journal of Pharmacy & Pharmacology, Chronicles of Pharmacy and SCIENCEDOMAIN international, and Scientific advisor for Journal of Pharmaceutical Sciences.

Affiliations and Expertise

School of Pharmacy, Queen's University Belfast, Medical Biology Centre, Belfast, UK

Ryan Donnelly

Professor Ryan Donnelly holds the Chair in Pharmaceutical Technology. His research is centred on design and physicochemical characterisation of advanced polymeric drug delivery systems for transdermal and topical drug delivery, with a strong emphasis on improving therapeutic outcomes for patients. His bioadhesive patch design was used successfully in the clinic and has now been licensed to Swedish Pharma AB, for whom he acts as a Scientific Advisor. He is currently developing a range of novel microneedle technologies through independent research, but also in collaboration with the world’s leading transdermal patch manufacturer and several major pharma partners. Still at a relatively early stage of his career, he has obtained substantial RCUK, charity and industrial funding and authored over 300 peer-reviewed publications, including 4 patent applications, 4 textbooks, 19 book chapters and approximately 130 full papers. He has been an invited speaker at numerous national and international conferences.

Affiliations and Expertise

School of Pharmacy, Queen's University Belfast, Medical Biology Centre, Belfast , UK