The major lipid components of biological membranes can undergo many diverse and fascinating morphological rearrangements. Studies of these diverse phases and the manner in which they are formed tends to alter the properties of ordinary bilayer membranes. This book examines the structural and biological roles of lipids forming non-lamellar structures.

Key Features

@introbul:Key Features @bul:* Characterization of non-lamellar structures * Protein activity and membrane properties * Analysis of membrane fusion * Affect of non-lamellar forming lipids on biological systems


Researchers and professionals in biophysics, cell biology, biochemistry, and chemistry.

Table of Contents

Characterization of Non-Lamellar Structures: V. Luzzati, H. Delacroix, A. Gulik, T. Gulik-Krzywicki, P. Mariani, and R. Vargas, The Cubic Phases of Lipids: Physico-chemical Properties and Biological Implications. R.N.A. Lewis, D.A. Mannock, and R.N. McElhaney, On the Relationship between Molecular Structure and the Lamellar/Nonlamellar Phase Behavior of Membrane Lipids. R.L. Thurmond and G. Lindblom, Deuterium and Pulsed Field Gradient NMR Studies of Membrane Lipid Properties. R.P. Rand and V.A. Parsegian, Hydration, Polymorphism, Membrane Curvature, and Bending Elasticity of Phospholipids. Perturbation of Bilayer Properties: J.C. Gómez-Fernández, J. Villalaén, and F. Aranda, The Phase Behavior of Model Membranes Containing Bioactive Lipids: A Comparison of a-tocopherol and Diacylglycerols. R.M. Epand, Modulation of Lipid Polymorphism by Peptides. Protein Activity and Membrane Properties: R. Zidovetzki, Role of Lipid Membrane Structure in the Mechanism of Activation of Protein Kinase C and Phospholipiase A2. M.F. Brown, Influence of Non-Lamellar Forming Lipids on the Photochemical Function and Conformational Energetics of Rhodopsin. Membrane Fusion: A.L. Bailey and P.R. Cullis, Liposome Fusion and Non-Bilayer Lipid Structures. P.L. Yeagle, Curvature of Phospholipid Surfaces and Fusion Pathways in Model and Biological Systems. K.N.J. Burger, Membrane Fusion in Model and Biological Systems: A Morphological Approach. Biological Systems: F.L. Sorgi and L. Huang, Drug Delivery Applications of Liposomes Containing Non-Bilayer Forming Phospholipids. B.


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© 1997
Academic Press
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@qu:"This volume 44 is an exceptional, up-to-date review of the current state of knowledge of nonlamellar phases and their relationship to biological processes of cellular membrane function... I enjoyed reading this volume. It was an excellent learning experience." @source:--Howard H. Sky-Peck, MD, PhD, FRSM, Rush Medical College of Rush University for DOODY'S PUBLISHING