Leucocyte Adhesion

Leucocyte Adhesion

1st Edition - November 9, 2009

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  • Editor: Klaus Ley
  • Hardcover ISBN: 9780123749093
  • eBook ISBN: 9780080956985

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Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. This volume provides a review of the latest developments in leukocyte adhesion. Regulation of cell adhesion is important for immune system function.

Key Features

  • Contributions from leading experts in the field
  • Reviews the latest developments
  • Readership

    Researchers in biochemistry, molecular and cellular biology and immunology

    Table of Contents

    • 1. Membrane composition and properties

      1. Lipid rafts (open)
      2. Membrane tethers (R Waugh, Rochester)
      3. Microvilli (JY Shao, Wash U)
      4. Whole cell deformation (D Khismatullin, Tulane)

      2. Adhesion molecules

      1. Integrin activation (M. Shimaoka, Harvard)
      2. Cytoskeletal anchoring (Fred Pavalko, Iowa)
      3. No tile yet (Alon, Weizman)
      4. Catch bonds (Cheng Zhu, Georgia Tech and Roger McEver, OMRF)
      5. Modeling adhesion (Pospieszalska/Ley, LIAI)
      6. Factors limiting the onset of bond formation at cell interfaces (R Waugh, Rochester)

      3. Active role of endothelial cells

      1. Adhesive platforms (O. Barreiro, Madrid)
      2. Migratory cups, podosomes (Chris Carman, Beth Israel)
      3. PECAM recycling (WA Muller, Northwestern)


      4. Methods

      1. FRET (Minsoo Kim, Rochester)

      2. Flow chambers (Simon SI at UC Davis)

    Product details

    • No. of pages: 300
    • Language: English
    • Copyright: © Academic Press 2009
    • Published: November 9, 2009
    • Imprint: Academic Press
    • Hardcover ISBN: 9780123749093
    • eBook ISBN: 9780080956985

    About the Editor

    Klaus Ley

    Affiliations and Expertise

    University of Virginia Health System, Cardiovascular Research Center, Charlottesville, USA

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