Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations.

Key Features

* Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.


Phytochemists; Combinatorial Chemists; Pharmacologists; Scientists engaged in Drug discovery and development; Industrial research groups developing drugs from plants; Departments of pharmaceutics; Institutes for Drug Research; Pharmaceutical companies; Manufacturers of herbal and ayurvedic medicines and cosmetic products Manufacturers of natural products

Table of Contents

Reverse Pharmacognosy: a new concept for accelerating natural drug discovery Quoc-Tuan DO and Philippe BERNARD Effects of Plant Extracts on Gene Expression Profiling: from Macrorrays to Microarray Technology Carlo Mischiati, Alessia Sereni, Mahmud Tareq Hassan Khan, Ilaria Lampronti and Roberto Gambari Effects of Medicinal Plant Extracts on Molecular Interactions between DNA and Transcription Factors Ilaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Giordana Feriotto1, Carlo Mischiati, Monica Borgatti and Roberto Gambari Plants with Antitumor Properties: from Biologically Active Molecules to Drugs Ilaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Elisabetta Lambertini, Roberta Piva, Monica Borgatti and Roberto Gambari Herbal Extracts and Compounds Active against Herpes Simplex Virus Kenneth D. Thompson Cough and its Pharmacological Modulation Nosalova, G., Mokry, J., Franova, S Phytotherapy of the Cough Franova, S., Nosalova G., Mokry, J. The Medicinal Potential of Black seed (Nigella sativa) and its Components Hala Gali-Muhtasib, Regine Schneider-Stock Cyclin Dependent Kinase Inhibitors from Natural Sources: Recent Advances and Future Prospects for Cancer Treatment Hala Gali-Muhtasib Anticancer and Medicinal Properties of Essential Oil and Extracts of East Mediterranean Sage (Salvia triloba) Hala Gali-Muhtasib Marine Organisms from Brazil as Source of Potential Anticancer Agents Letícia Veras Costa-Lotufo, Cláudia Pessoa, Maria Elisabete A. Moraes, Adaíla Marta Paixão Almeida, Manoel Odorico de Moraes, Tito Monteiro da Cruz Lotufo


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© 2006
Elsevier Science
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