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Laboratory Animal Anaesthesia - 4th Edition - ISBN: 9780128000366, 9780128005781

Laboratory Animal Anaesthesia

4th Edition

Author: Paul Flecknell
eBook ISBN: 9780128005781
Hardcover ISBN: 9780128000366
Imprint: Academic Press
Published Date: 21st September 2015
Page Count: 350
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Laboratory Animal Anaesthesia, Fourth Edition provides a basic guide to anaesthesia for a very diverse audience needing content, with straight-forward, structured style of writing. Updated with effects of anaesthetics in different laboratory species, including sources of dose rates will be incorporated into tabular material. New information on pain assessment and pain management will be covered, and an increased emphasis on rats and mice for anaesthesia and perioperative care. With newly revised, full color illustrations to facilitate best learning, Laboratory animal Anesthesia, Fourth Edition provides procedures, key points and invaluable advice from a well-known and respected veterinary anesthetist and scientist with over 30 years of experience in the field.

Key Features

  • Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area
  • Focuses on procedures involving rats and mice used in research
  • Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely, as well as those with more experience to continue a career with laboratory animal model research
  • Includes rapid, easily accessed information using tabulated summaries


Researchers, graduate students and veterinarians in all fields across biological and biomedical research, animal technicians, animal care staff, veterinary anaesthetists, and veterinarians

Table of Contents

Chapter 1. Basic Principles of Anaesthesia

  • Introduction: What is Anaesthesia and How Do We Produce it?
  • Anaesthetic Equipment – Preparation and Use
  • Intranasal Intubation
  • Administration of Anaesthetics by Injection
  • Preparations for Anaesthesia – People and Animals
  • Anaesthetic Agents
  • Inhalational Anaesthetic Agents
  • Injectable Anaesthetic Agents
  • Selection of Anaesthetic Agents – Scientific and Welfare Considerations

Chapter 2. Managing and Monitoring Anaesthesia

  • Pre-operative Preparations
  • Monitoring Anaesthesia
  • Anaesthetic Problems and Emergencies

Chapter 3. Special Techniques

  • Use of NMB Agents
  • Controlled Ventilation
  • Long-Term Anaesthesia
  • Anaesthesia of Pregnant Animals
  • Anaesthesia of Neonates
  • Anaesthesia for Imaging

Chapter 4. Analgesia and Post-Operative Care

  • The Recovery Room Environment
  • Problems During the Recovery Period
  • Management of Post-Operative Pain
  • Pain Assessment
  • Pain Relief
  • Conclusions

Chapter 5. Anaesthesia of Common Laboratory Species: Special Considerations

  • Small Rodents
  • Rabbits
  • Post-Operative Care
  • Cats
  • Dogs
  • Ferrets
  • Pigs
  • Sheep and Goats
  • Primates
  • Other Species

Appendix 1. Recommended Techniques and Physiological Data. When No Injectable Anaesthetic Is Recommended, Inhalational Agents Should Be Used

Appendix 2. Estimation of Required Quantities of Volatile Anaesthetics and Anaesthetic Gases

Appendix 3. Examples of Dilutions of Anaesthetic Mixtures for Small Rodents

  • Rat
  • Mouse
  • Guinea-Pig
  • Birds

Appendix 4. Manufacturers of Equipment and Other Items Illustrated or Cited in the Text


No. of pages:
© Academic Press 2015
21st September 2015
Academic Press
eBook ISBN:
Hardcover ISBN:

About the Author

Paul Flecknell

Paul Flecknell is a veterinarian with over 35 years of experience working with laboratory animals. He is a Diplomate of the European Colleges of Veterinary Anaesthesia and Analgesia and Laboratory Animal Medicine and an honorary Diplomate of the American College of Laboratory Animal Medicine. He has PhD in physiology, and is currently Professor of Laboratory Animal Science in the Institute of Neuroscience at Newcastle University. His main research interests are anaesthesia and analgesia of all species of animals and in particular the development of methods of pain assessment. He is the head of the Pain and Animal Welfare Science (PAWS) group at Newcastle. The group’s current research work is focussed on novel methods of “cage-side” assessment of pain, particularly using “pain faces” and developing methods of measurement of affective state in rodents.

Affiliations and Expertise

Comparative Biology Centre, The Medical School, Newcastle-Upon-Tyne, UK


"...a must have for any laboratory animal professional involved with anesthetizing research animals…an affordable essential reference for research personnel, laboratory animal veterinarians, and students." --Journal of the American Veterinary Medical Association

"The preeminent book on laboratory animal anesthesia and analgesia...It is easy to locate information in this one-stop resource on laboratory animal anesthesia...a well organized book that ensures readers are aware of the most important clinical aspects of a topic. Score: 99 - 5 Stars" --Doody's

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