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Ischemic and Traumatic Brain and Spinal Cord Injuries - 1st Edition - ISBN: 9780128135969, 9780128135976

Ischemic and Traumatic Brain and Spinal Cord Injuries

1st Edition

Mechanisms and Potential Therapies

Author: Akhlaq Farooqui
Paperback ISBN: 9780128135969
eBook ISBN: 9780128135976
Imprint: Academic Press
Published Date: 21st March 2018
Page Count: 484
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Description

Ischemic and Traumatic Brain and Spinal Cord Injuries: Mechanisms and Potential Therapies presents readers with comprehensive and cutting-edge information on molecular mechanisms, including the signal transduction processes associated with neurodegeneration and neuroprotection in ischemic, spinal cord, severe and mild brain injuries. The book also covers the molecular mechanisms of drugs used for the treatment of neurotraumatic disease. Chapters are organized by molecular aspects and neuroprotective strategies by disease, including ischemic injury, spinal cord injury, traumatic brain injury, and chronic traumatic encephalopathy.

The book integrates and consolidates knowledge on neurotraumatic diseases, with the hope of bringing forth more dramatic advances and developments, not only on molecular mechanisms, but also on the causes of, and treatments for, neurotraumatic diseases.

Key Features

  • Offers a clearly written, logically organized, comprehensive overview on the molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies for ischemic, spinal cord, severe and mild brain injuries
  • Provides cutting-edge research information on the signal transduction processes associated with neurodegeneration and neuroprotection in ischemic, spinal cord, severe and mild brain injuries
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  • Presents chapters that are organized by molecular aspects and neuroprotective strategies by disease, including ischemic injury, spinal cord injury, traumatic brain injury, and chronic traumatic encephalopathy

Readership

Researchers, Practitioners and advanced graduate students in Neuroscience, Neurology, and Pharmacology

Table of Contents

  1. Classification and molecular aspects of neurotraumatic diseases
    2. Molecular Aspects of Ischemic Injury
    3. Potential neuroprotective strategies for ischemic injury
    4. Molecular Aspects of Spinal Cord Injury
    5. Potential neuroprotective strategies for spinal cord injury
    6. Molecular Aspects of traumatic brain injury
    7. Potential neuroprotective strategies for traumatic brain injury
    8. Molecular Aspects of chronic traumatic encephalopathy
    9. Potential neuroprotective strategies for chronic traumatic encephalopathy
    10. Summery and perspective for future research on ischemic, traumatic brain and spinal cord injuries

Details

No. of pages:
484
Language:
English
Copyright:
© Academic Press 2018
Published:
21st March 2018
Imprint:
Academic Press
Paperback ISBN:
9780128135969
eBook ISBN:
9780128135976

About the Author

Akhlaq Farooqui

Akhlaq Farooqui

Akhlaq A. Farooqui is a leader in the field of signal transduction processes, lipid mediators, phospholipases, glutamate neurotoxicity, and neurological disorders. He is a research scientist in the Department of Molecular and Cellular Biochemistry at The Ohio State University. He has published cutting edge research on the role of phospholipases A2 in signal transduction processes, generation and identification of lipid mediators during neurodegeneration by lipidomics. He has studied the involvement of glycerophospholipid, sphingolipid-, and cholesterol-derived lipid mediators in kainic acid neurotoxicity, an experimental model of neurodegenerative diseases. Akhlaq A. Farooqui has discovered the stimulation of plasmalogen- selective phospholipase A2 in brains of patients with Alzheimer disease (AD). Stimulation of this enzyme may not only be responsible for the deficiency of plasmalogens in neural membranes of AD patients, but also be related to the loss of synapse in the AD.

Affiliations and Expertise

Research Scientist, Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, USA

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