
Introduction to Enzymology
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Introduction to Enzymology focuses on the processes, methodologies, reactions, and approaches involved in enzyme chemistry. The book first offers information on the hydrolysis of peptides and proteins and fermentation and oxidation of major metabolic fuels. Discussions focus on oxidation of fatty acids, alternative pathways of carbohydrate metabolism, Krebs citric acid cycle, free energy and the concept of bond energy, pyruvate oxidation and acetyl coenzyme A formation, and glycolysis. The text then elaborates on the transfer of oxygen, hydrogen, and electrons and sugars and sugar derivatives. The publication takes a look at polynucleotides and their components, amino acids, and acids and acid derivatives. Topics include carbonic anhydrase, mechanism of action of pyridoxal phosphate enzymes, aromatic ring biosynthesis and metabolism of phenylalanine and tyrosine, metabolism of sulfur-containing amino acids, and oxidation of amino acids. The book is a valuable reference for chemists and researchers interested in enzymology.
Table of Contents
Preface
I. Introduction
II. Hydrolysis of Peptides and Proteins
III. Fermentation and Oxidation of Major Metabolic Fuels
Glycolysis
Pyruvate Oxidation and Acetyl Coenzyme A Formation
Free Energy and the Concept of Bond Energy
Reactions of Coenzyme A
The Krebs Citric Acid Cycle
Alternative Pathways of Carbohydrate Metabolism
Oxidation of Fatty Acids
IV. Biological Oxidation: Tranfer of Oxygen, Hydrogen, and Electrons
Pyridine Nucleotides
Oxidation-Reduction Potentials
Flavoproteins
Cytochromes
The Hydroperoxidases: Catalase and Peroxidase
Oxidases and Oxygenases
V. Sugars and Sugar Derivatives
Polysaccharides
Reactions of Uridine Nucleotides
VI. Polynucleotides and their Components
Nucleic Acids
Purines and Pyrimidines
VII. Amino Acids
Amino Acid Decarboxylases
Transamination
Oxidation of Amino Acids
Glutamic Acid and Amino Acids Derived from It
Aspartic Acid, Threonine, and Lysine
The Urea Cycle
β-Hydroxy-α-amino Acids
Metabolism of Sulfur-Containing Amino Acids
Histidine
Aromatic Ring Biosynthesis and Metabolism of Phenylalanine and Tyrosine
Tryptophan
Mechanism of Action of Pyridoxal Phosphate Enzymes
Metabolism of Amines
VIII. Acids and Acid Derivatives
Esters
Carbonic Anhydrase
IX. Organization of Structure and Function
Integration of Biochemical Reactions
Adaptive Enzymes and the Synthesis of Proteins
Appendix: Abbreviations
Subject Index
Product details
- No. of pages: 439
- Language: English
- Copyright: © Academic Press 1957
- Published: January 1, 1957
- Imprint: Academic Press
- eBook ISBN: 9781483258478