International Review of Connective Tissue Research

International Review of Connective Tissue Research

Volume 10

1st Edition - October 1, 1983

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  • Editors: David A. Hall, D. S. Jackson
  • eBook ISBN: 9781483191720

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International Review of Connective Tissue Research is a compilation of scientific research mainly focuses on developments in special tissues. A detailed discussion of the lung and liver is included. Another topic of interest is the liver fibrosis development induced by parasitic infection or alcohol. The periodontal ligament is specialized tissue whose basic role is tooth support. This tissue is covered in detail. A section of the book provides an analysis of the elastin gene expression and regulation. Topics such as the microfibrillar components of connective tissue, the regulation of collagen genes, the complexity and the evolution of the collagen molecule, the invasiveness of malignant tumors, and the characteristics of fibroblast are fully explained. The text presents an exhaustive description of the connective tissue of the lung. This chapter includes a comprehensive description of the pulmonary system. The book will provide useful information to doctors, students, researchers and specialists in the field of human anatomy.

Table of Contents

  • Contributors


    Contents of Previous Volumes

    The Structure of Collagen Genes

    I. Introduction

    II. Characterization of Collagen Genes

    III. Fibrillar Collagen Genes

    IV. Nonfibrillar Invertebrate Collagen Genes

    V. Some Speculations on Collagen Gene Structure


    Elastin Gene Expression

    I. Introduction

    II. Isolation of Elastin mRNAs

    III. Cell-Free Translation of Elastin mRNAs

    IV. Identification of Tropoelastin

    V. Tropoelastin Synthesis in Organ Culture

    VI. The Signal Peptide of Tropoelastin b

    VII. Distribution of Tropoelastins a and b

    VIII. Differential Expression of Tropoelastins a and b during Development

    IX. Effect of Glucocorticoids on Elastin Synthesis

    X. Synthesis and Cloning of Elastin cDNA

    XI. Conclusion


    Elastin-Associated Microfibrils and Microfibrillar Proteins

    I. Introduction and Historical Overview

    II. Nomenclature

    III. Elastin-Associated Microfibrils in Normal Tissues

    IV. Oxytalan, Elaunin, and Elastin-Associated Microfibrils

    V. Elastin-Associated Microfibrils in Disease

    VI. Microfibrils in Nonelastic Tissues

    VII. Concluding Remarks


    Periodontal Ligament

    I. Introduction

    II. Cells

    III. Fibers in the Periodontal Ligament

    IV. Periodontal Ligament Collagen

    V. Noncollagenous Components of Periodontal Ligament

    VI. Glycosaminoglycans/Proteoglycans

    VII. Glycoproteins

    VIII. Periodontal Ligament Fibroblasts

    IX. Concluding Remarks


    Lung Connective Tissue

    I. Introduction

    II. General Considerations

    III. Lung Connective Tissues

    IV. Remodeling of Lung Connective Tissue

    V. Concluding Remarks


    Liver Fibrosis

    I. Introduction

    II. Connective Tissue of the Normal Liver

    III. Liver Fibrosis

    IV. Outlook for Treatment


    Connective Tissue Changes in Cancer

    I. Introduction

    II. The Etiology of Stromal Involvement

    III. Morphology of Stromal Changes

    IV. Quantitative Studies on Collagen during Carcinogenesis

    V. Lytic Enzymes in Cancer

    VI. Elastin during Carcinogenesis

    VII. Fibronectin in Cancer

    VIII. Stromal Glycosaminoglycans in Cancer

    IX. Stromal Mast Cells in Cancer

    X. Stromal Changes Associated with Vascular Proliferation

    XI. Phenomena at the Epithelial-Stromal Junction

    XII. Transplantation Experiments

    XIII. Data on Tumors of Mesenchymal Origin

    XIV. Concluding Remarks



Product details

  • No. of pages: 464
  • Language: English
  • Copyright: © Academic Press 1983
  • Published: October 1, 1983
  • Imprint: Academic Press
  • eBook ISBN: 9781483191720

About the Editors

David A. Hall

D. S. Jackson

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