International Review of Cell and Molecular Biology - 1st Edition - ISBN: 9780128022825, 9780128024805

International Review of Cell and Molecular Biology, Volume 315

1st Edition

Editors: Kwang Jeon
eBook ISBN: 9780128024805
Hardcover ISBN: 9780128022825
Imprint: Academic Press
Published Date: 26th February 2015
Page Count: 344
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Table of Contents

  • Chapter One. How Rab Proteins Determine Golgi Structure

    • 1. Introduction
    • 2. Rab Proteins and Their Subfamilies
    • 3. Golgi Apparatus and Its Organization
    • 4. Two Major Functional/Phenotypic Classes of Rab Proteins Based on Their Effects on Golgi Ribbon Organization
    • 5. Mechanistic Effect of Rab Proteins on Golgi Ribbon Organization
    • 6. Conclusions and Perspectives
  • Chapter Two. Amyotrophic Lateral Sclerosis as a Spatiotemporal Mislocalization Disease: Location, Location, Location

    • 1. Introduction
    • 2. Amyotrophic Lateral Sclerosis
    • 3. Axonal Transport
    • 4. RNA-Binding Proteins
    • 5. Neurotrophic Factors and Their Precursor Forms
    • 6. Death Signals
    • 7. Amyloid Precursor Protein
    • 8. Concluding Remarks
  • Chapter Three. Malleable Mitochondrion of Trypanosoma brucei

    • 1. Introduction
    • 2. Maintenance and Expression of Genetic Information
    • 3. Mitochondrial Import
    • 4. Mitochondrial Metabolism
    • 5. Structural Proteins and Fission
    • 6. Concluding Remarks
  • Chapter Four. Heredity and Self-Organization: Partners in the Generation and Evolution of Phenotypes

    • 1. Introduction
    • 2. Self-Organization in Biology
    • 3. Internal Descriptions, Developmental Limitations and Buffering Variation
    • 4. Conclusions
  • Chapter Five. Nuclear Compartments, Genome Folding, and Enhancer-Promoter Communication

    • 1. Introduction
    • 2. Juxtaposition of Genome Regulatory Elements: Active Chromatin Hub or Active Nuclear Compartment?
    • 3. Dynamic Contacts rather than Rigid Complexes
    • 4. Driving Forces of Communication within Cell Nucleus
    • 5. Functional Compartmentalization of Eukaryotic Cell Nucleus
    • 6. Nuclear Compartmentalization and Chromosome Folding: A


International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.

The series has a world-wide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.

Key Features

  • Authored by some of the foremost scientists in the field
  • Provides comprehensive reviews and current advances
  • Wide range of perspectives on specific subjects
  • Valuable reference material for advanced undergraduates, graduate students and professional scientists


Cell biologists, molecular biologists, developmental biologists, physiologists (organ level), biomedical scientists, biochemists studying cell-cell interactions, cell variation and evolution, students and researchers.


No. of pages:
© Academic Press 2015
Academic Press
eBook ISBN:
Hardcover ISBN:

Ratings and Reviews

About the Editors

Kwang Jeon Editor

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and Expertise

University of Tennessee, Knoxville, TN, USA