International Review of Cell and Molecular Biology, Volume 287

1st Edition

Editors: Kwang Jeon
Hardcover ISBN: 9780123860439
eBook ISBN: 9780123860446
Imprint: Academic Press
Published Date: 29th March 2011
Page Count: 348
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Table of Contents


  • Structure and Functions of Aquaporin-4-Based Orthogonal Arrays of Particles
    • 1. Introduction
    • 2. General Properties of OAPs and AQP4
    • 3. OAPs and AQP4 in Cells Outside the Central Nervous System
    • 4. OAPs and AQP4 in Cells of the Central Nervous System
    • 5. OAPs and AQP4 in Reactive Astrocytes, Glioma, and Inflammation
    • 6. Conclusions and Outlook
    • Acknowledgments

  • Interpreting the Stress Response of Early Mammalian Embryos and Their Stem Cells
    • Abbreviations
    • 1. Introduction
    • 2. Stress and Stress Enzymes
    • 3. Stress Responses
    • 4. Roles of Stress Enzymes
    • 5. Models and Lessons
    • 6. Summary, Significance, and Future Studies
    • Acknowledgments

  • Directional Cell Migration
    • 1. Introduction
    • 2. Cell Movement
    • 3. Small G Proteins and Leading Edge Structures
    • 4. Nectins, Necls, and Afadin
    • 5. Crosstalk between Growth Factor Receptors and Integrins
    • 6. Regulation of Directionality of Cell Movement
    • 7. Regulation of Dynamics of Cyclical Activation and Inactivation of Small G Proteins by Afadin
    • 8. Concluding Remarks
    • Acknowledgments

  • Mitochondrial RNA Import
    • 1. Introduction
    • 2. RNA Import in Protozoa
    • 3. RNA Import in Plants
    • 4. RNA Import in Fungi
    • 5. RNA Import in Metazoa
    • 6. Potential Applications of Macromolecule Import
    • 7. Conclusion and Prospects

  • New Insights into Vinculin Function and Regulation
    • 1. Introduction
    • 2. Vinculin Structure
    • 3. Autoinhibited Conformation and Vinculin Activation
    • 4. Biological Functions
    • 5. Modes of Vinculin Regulation
    • 6. Emerging Themes and Concepts
    • 7. Inter


International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2009: 6.088.

Key Features

Authored by some of the foremost scientists in the field
Provides up-to-date information and directions for future research
* Valuable reference material for advanced undergraduates, graduate students and professional scientists


Cell biologists, molecular biologists, developmental biologists, physiologists (organ level), biomedical scientists, biochemists studying cell-cell interactions, cell variation and evolution


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© Academic Press 2011
Academic Press
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Hardcover ISBN:

About the Editors

Kwang Jeon Editor

Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.

Affiliations and Expertise

University of Tennessee, Knoxville, TN, USA