Integrins

Integrins

Molecular and Biological Responses to the Extracellular Matrix

1st Edition - September 26, 1994

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  • Editor: Robert Mecham
  • eBook ISBN: 9780080917290

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Description

Integrins: Molecular and Biological Responses to the Extracellular Matrix will help basic, applied, and clinical researchers keep up with the explosion of literature on the integrin family of proteins. This volume extends material previously covered in Receptors for Extracellular Matrix. It addresses some of the most exciting areas of integrin biology, including the varied roles of integrins in cell division, differentiation, movement, wound healing, inflammation, thrombosis, osteoporosis, and cancer.

Key Features

  • Describes key aspects of integrin structure, function, and biology
  • Covers collagen receptors, epithelial cell integrins, leukocyte integrins, platelet integrins, integrin signaling, and integrin antagonists
  • Investigates the expression and role of integrins during development and in the cytoskeleton
  • Includes the actions and influences of integrins in inflammation, thrombosis, and osteoporosis

Table of Contents

  • J.W. SMITH, The Structural Basis of Integrin-Ligand (RGD) Interaction. M.A. SCHWARTZ, Integrins as Signal Transducing Receptors. K.O. SIMON and K. BURRIDGE, Interactions Between Integrins and the Cytoskeleton: Structure and Regulation. J ASHKENAS, C.H. DAMSKY, M.J. BISSELL, And Z.WERB, Integrins, Signaling, And the Remodeling of the Extracellular Matrix. T. LALLIER, M.D. HENS, And D.W. DESIMONE, Integrins in Development. V QUARANTA, R.N. TAMURA, G. COLLO, H.M. COOPER, M. HORMIA, C. ROZZO, G. GAIETTA, And L. STARR, Distinctive Functions of Alpha6beta4 and Other Interactions in Epithelial Cells. M.J. ELICES, Leukocyte Integrins. T.J. KUNICKI and Z.R. RUGGERI, Molecular Properties of Human Platelet Integrin Alphaiibbeta3. J.M. STADEL, A.J. NICHOLS, D.R. BERTOLINI, And J.M. SAMANEN, Therapeutic Potential of Integrin Antagonists. Subject Index.

Product details

  • No. of pages: 278
  • Language: English
  • Copyright: © Academic Press 2012
  • Published: September 26, 1994
  • Imprint: Academic Press
  • eBook ISBN: 9780080917290

About the Series Editor

Robert Mecham

Affiliations and Expertise

Washington University, St. Louis, Missouri, U.S.A.

About the Series Volume Editor

David Cheresh

Affiliations and Expertise

The Scripps Research Institute, La Jolla, CA, USA

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