Insect Molecular Biology and Biochemistry

1st Edition

Editors: Lawrence Gilbert
Hardcover ISBN: 9780123847478
eBook ISBN: 9780123847485
Imprint: Academic Press
Published Date: 16th August 2011
Page Count: 574
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The publication of the extensive seven-volume work Comprehensive Molecular Insect Science provided a complete reference encompassing important developments and achievements in modern insect science. One of the most swiftly moving areas in entomological and comparative research is molecular biology, and this volume, Insect Molecular Biology and Biochemistry, is designed for those who desire a comprehensive yet concise work on important aspects of this topic.

This volume contains ten fully revised or rewritten chapters from the original series as well as five completely new chapters on topics such as insect immunology, insect genomics, RNAi, and molecular biology of circadian rhythms and circadian behavior. The topics included are key to an understanding of insect development, with emphasis on the cuticle, digestive properties, and the transport of lipids; extensive and integrated chapters on cytochrome P450s; and the role of transposable elements in the developmental processes as well as programmed cell death. This volume will be of great value to senior investigators, graduate students, post-doctoral fellows and advanced undergraduate research students. It can also be used as a reference for graduate courses and seminars on the topic. Chapters will also be valuable to the applied biologist or entomologist, providing the requisite understanding necessary for probing the more applied research areas related to insect control.

Key Features

  • Topics specially selected by the editor-in-chief of the original major reference work
  • Fully revised and new contributions bring together the latest research in the rapidly moving fields of insect molecular biology and insect biochemistry, including coverage of development, physiology, immunity and proteomics
  • Full-color provides readers with clear, useful illustrations to highlight important research findings

Table of Contents



1. Insect Genomics

1.1. Introduction

1.2. Genome Sequencing

1.3. Genome Analysis

1.4. Proteomics

1.5. Structural Genomics

1.6. Metabolomics

1.7. Systems Biology

1.8. Conclusions and Future Prospects

2. Insect MicroRNAs

2.1. Introduction: The Big World of Small RNAs

2.2. Biogenesis of miRNAs

2.3. Mechanism of Action of miRNAs

2.4. Identification of miRNAs in Insects

2.5. Target Prediction

2.6. miRNA Functions

2.7. Conclusions and Perspectives

3. Insect Transposable Elements

3.1. Introduction

3.2. Classification and Transposition Mechanisms of Eukaryotic Transposable Elements

3.3. Methods to Uncover and Characterize Insect TEs

3.4. Diversity and Characteristics of Insect TEs

3.5. Search for Active TEs in Insect Genomes

3.6. Evolution of Insect TEs

3.7. TEs in Insect Populations

3.8. Impact of TEs in Insects

3.9. Applications of Insect TEs

3.10. Summary

4. Transposable Elements for Insect Transformation

4.1. Introduction

4.2. P Element Transformation

4.3. Excision and Transposition Assays for Vector Mobility

4.4. Transformation Marker Systems

4.5. Transposon Vectors

4.6. Transformation Methodology

4.7. Summary

5. Cuticular Proteins

5.1. Introduction

5.2. Cuticle Structure and Synthesis

5.3. Classes of Proteins Found in Cuticles

5.4. Genomic Information

5.5. Interactions of Cuticular Proteins with Components of Cuticle

5.6. Summary and Future Challenges

6. Cuticular Sclerotization and Tanning

6.1. Introduction

6.2. A Model for Cuticular Sclerotization

6.3. Sclerotization (Tanning) Precursors

6.4. Transport of Sclerotization Precursors


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About the Editor

Lawrence Gilbert

Affiliations and Expertise

Department of Biology, University of North Carolina, Chapel Hill, NC