Inositol Phospholipid Metabolism and Phosphatidyl Inositol Kinases - 1st Edition - ISBN: 9780444513212, 9780080930305

Inositol Phospholipid Metabolism and Phosphatidyl Inositol Kinases, Volume 30

1st Edition

Editors: A. Kuksis
Hardcover ISBN: 9780444513212
eBook ISBN: 9780080930305
Imprint: Elsevier Science
Published Date: 12th September 2003
Page Count: 1000
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Table of Contents

Chapter 1. General introduction. 1.1 Introduction. 1.2 Natural occurrence. 1.3 Biological significance. 1.4 Nomenclature. 1.5 Scope of the book. 1.6 References. Chapter 2. Phosphatidylinositols. 2.1 Isolation. 2.2 Identification. 2.3 Quantification. 2.4 References. Chapter 3. Phosphatidylinositol phosphates. 3.1 Isolation. 3.2 Determination of structure. 3.3 Resolution of molecular species. 3.4 Quantification. 3.5 References. Chapter 4. Inositol phosphates. 4.1 Introduction. 4.2 Isolation. 4.3 Resolution of chemical subclasses. 4.4 Resolution of positional isomers. 4.5 Determination of chemical structure. 4.6 Determination of stereochemical structure. 4.7 Quantification. 4.8 References.

Chapter 5. Glycosylphosphatidylinositols. 5.1 Introduction. 5.2 National occurrence and isolation. 5.3 Determination of chemical structure. 5.4 Determination of molecular species. 5.5 Quantification. 5.6 Related structures. 5.7 References. Chapter 6. Biosynthesis of inositol phospholipids. 6.1 Introduction. 6.2 Phosphatidylinositols. 6.3. Phosphatidylinositol phosphates. 6.4 Glycosyl phosphatidylinositols. 6.5. References. Chapter 7. Phosphatidylinositol and inositol phosphate kinases. 7.1 Introduction. 7.2 Phosphatidylinositol kinases. 7.3 Phosphatidylinositol monophosphate kinases. 7.4 Phosphatidylinositol bisphosphate kinases. 7.5 Inositol monophosphate kinases. 7.6 Inositol bisophosphate kinases. 7.7 Inositol trisphosphate kinases. 7.8 Inositol tetrakisphosphate kinases. 7.9 Inositol pentakisphosphate kinases. 7.10 Inositol hexakisphosphate kinases. 7.11 References. Chapter 8. Phosphatidylinositol phosphate and inositol phosphate phosphatases. 8.1 Introduction. 8.2 PtdIns phosphate phosphatases. 8.3 Inositol phosphate phosphatases. 8.4 Other phosphatases and phytases. 8.5 References. Chapter 9. Phosphatidylinositol phospholipases. 9.1 Introduction. 9.2 PtdIns-nonspecific phospholipases. 9.3 PtdIns-specific phospholipases. 9.4 PtdIns(4,5)P2 activated phospholipases. 9.5 PtdIns(3,4,5)P3 activated phospholipases. 9.6 References. Chapter 10. Preparation of standards. 10.1 Introduction. 10.2 Phosphatidylinositol phosphates. 10.3 Inositol phosphates. 10.4 Inositol pyrosphosphates. 10.5 Structural analogues. 10.6 References. Chapter 11. InsPs and PtdInsPs as signaling molecules. 11.1 Introduction. 11.2 InsPs as cellular signals. 11.3 PtdInsPs as cellular signals. 11.4 References.


Description

Chapter 1. General introduction. 1.1 Introduction. 1.2 Natural occurrence. 1.3 Biological significance. 1.4 Nomenclature. 1.5 Scope of the book. 1.6 References. Chapter 2. Phosphatidylinositols. 2.1 Isolation. 2.2 Identification. 2.3 Quantification. 2.4 References. Chapter 3. Phosphatidylinositol phosphates. 3.1 Isolation. 3.2 Determination of structure. 3.3 Resolution of molecular species. 3.4 Quantification. 3.5 References. Chapter 4. Inositol phosphates. 4.1 Introduction. 4.2 Isolation. 4.3 Resolution of chemical subclasses. 4.4 Resolution of positional isomers. 4.5 Determination of chemical structure. 4.6 Determination of stereochemical structure. 4.7 Quantification. 4.8 References.

Chapter 5. Glycosylphosphatidylinositols. 5.1 Introduction. 5.2 National occurrence and isolation. 5.3 Determination of chemical structure. 5.4 Determination of molecular species. 5.5 Quantification. 5.6 Related structures. 5.7 References. Chapter 6. Biosynthesis of inositol phospholipids. 6.1 Introduction. 6.2 Phosphatidylinositols. 6.3. Phosphatidylinositol phosphates. 6.4 Glycosyl phosphatidylinositols. 6.5. References. Chapter 7. Phosphatidylinositol and inositol phosphate kinases. 7.1 Introduction. 7.2 Phosphatidylinositol kinases. 7.3 Phosphatidylinositol monophosphate kinases. 7.4 Phosphatidylinositol bisphosphate kinases. 7.5 Inositol monophosphate kinases. 7.6 Inositol bisophosphate kinases. 7.7 Inositol trisphosphate kinases. 7.8 Inositol tetrakisphosphate kinases. 7.9 Inositol pentakisphosphate kinases. 7.10 Inositol hexakisphosphate kinases. 7.11 References. Chapter 8. Phosphatidylinositol phosphate and inositol phosphate phosphatases. 8.1 Introduction. 8.2 PtdIns phosphate phosphatases. 8.3 Inositol phosphate phosphatases. 8.4 Other phosphatases and phytases. 8.5 References. Chapter 9. Phosphatidylinositol phospholipases. 9.1 Introduction. 9.2 PtdIns-nonspecific phospholipases. 9.3 PtdIns-specific phospholipases. 9.4 PtdIns(4,5)P2 activated phospholipases. 9.5 PtdIns(3,4,5)P3 activated phospholipases. 9.6 References. Chapter 10. Preparation of standards. 10.1 Introduction. 10.2 Phosphatidylinositol phosphates. 10.3 Inositol phosphates. 10.4 Inositol pyrosphosphates. 10.5 Structural analogues. 10.6 References. Chapter 11. InsPs and PtdInsPs as signaling molecules. 11.1 Introduction. 11.2 InsPs as cellular signals. 11.3 PtdInsPs as cellular signals. 11.4 References.


Details

No. of pages:
1000
Language:
English
Copyright:
© Elsevier Science 2003
Published:
Imprint:
Elsevier Science
eBook ISBN:
9780080930305
Paperback ISBN:
9780444513045

Reviews

"In this excellent new book, Kuksis shows how our knowledge of the remarkable activities of these compounds has only been possible because of the continuous development of novel analytical methodologies...In short, it is hard to conceive of a more comprehensive and thorough guide to the subject of analysis and biochemistry of phosphatidylinositol and its metabolites. It is quite remarkable that this substantial book has been produced by single author, especially as this leads to a uniformity of treatment in the various chapters impossible to achieve in multi-author volumes. Every biochemistry and lipid library should have a copy." --William W. Christie, MRS Lipid Analysis Unit, Scottish Crop research Institute, Invergowrie, Dundee, Scotland for LIPID TECHNOLOGY NEWSLETTER, December 2003


About the Editors

A. Kuksis Editor

Affiliations and Expertise

Banting and Best Department of Medical Research, University of Toronto, Canada