Implantable Sensor Systems for Medical Applications

1st Edition

Editors: Andreas Inmann Diana Hodgins
Hardcover ISBN: 9781845699871
eBook ISBN: 9780857096289
Imprint: Woodhead Publishing
Published Date: 2nd January 2013
Page Count: 544
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Table of Contents

Contributor contact details

Woodhead Publishing Series in Biomaterials



Part I: Fundamentals of implantable systems

Chapter 1: Materials for implantable systems


1.1 Introduction

1.2 Interactions between materials and the biological medium

1.3 Electrodes

1.4 Preferred electrode metals, compounds and polymers

1.5 Leads and interconnects

1.6 Packaging

1.7 Surface preparation

1.8 Conclusions

1.9 Future trends

1.10 Sources of further information

1.11 Acknowledgements

Chapter 2: Material–tissue interfaces in implantable systems


2.1 Introduction

2.2 Fundamental requirements of material–tissue interfaces

2.3 Material selection for implantable systems

2.4 Design considerations and packaging concepts

2.5 Approaches to reduce reactions at the material–tissue interface

2.6 Conclusions

2.7 Future trends

2.8 Sources of further information

Chapter 3: Packaging and coating materials for implantable devices


3.1 Introduction

3.1.1 Background

76 Implantable sensor systems for medical applications 3.1.3 Current packaging and coating strategies

3.2 Packaging of the passive device surface

80 Implantable sensor systems for medical applications 3.2.2 Silicone

3.3 Coating of active device surfaces

3.4 Coatings and barriers for drug release

3.5 Enhancement of surface biocompatibility

3.6 Conclusions

3.7 Future trends

Chapter 4: Microassembly and micropackaging of implantable systems


4.1 Introduction

4.2 Components of an implanted sensor system

4.3 Microassembly

4.4 Micropackaging

4.5 Conclusions

4.6 Future trends

4.7 Sources of furthe


Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications.

Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanical systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants.

With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies.

Key Features

  • Provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of implantable sensor systems in a range of medical applications
  • Reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, and microassembly
  • Considers the challenges associated with implantable systems, including biocompatibility and sterilization


Technology providers, device manufacturers and clinical manufacturers


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© Woodhead Publishing 2013
Woodhead Publishing
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The book really illustrates the complexity when it comes to biosensor development and implantation, which will encourage a lot of researchers to broaden their perspective beyond their own research area., Drs. Elke Van De Walle, Ghent University, Belgium. Biomaterials Network

About the Editors

Andreas Inmann Editor

Dr. Andreas Inmann is a consultant and entrepreneur specializing in the development and commercialization of medical devices.

Affiliations and Expertise

Andreas Inmann Consulting, USA

Diana Hodgins Editor

Dr. Diana Hodgins is Managing Director of European Technology for Business, Ltd., a UK-based company that specializes in the design of microsystems and sensors.

Affiliations and Expertise

European Technology for Business Limited, UK