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Immunology of Endometriosis - 1st Edition - ISBN: 9780128206614

Immunology of Endometriosis

1st Edition

Pathogenesis and Management

Editor: Kaori Koga
Paperback ISBN: 9780128206614
Imprint: Academic Press
Published Date: 26th November 2021
Page Count: 216
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Table of Contents

Section 1 - Immune factors in the pathogenesis, and the potential therapeutic target, of endometriosis

1. Immune factors in the pathogenesis, and the potential therapeutic target, of endometriosis

2. Macrophages - They came, they saw, they conquered

3. Dendritic cells

4. Neutrophils

5. Th1, Th2, Th17, and regulatory T cells

6. Auto-immune factors: Evidence, Mechanism and Therapeutic Potential

7. Estrogen and estrogen-related factors

8. Hypoxia

9. The role of immune factors in the endometriosis-associated conditions

Section 2 - The role of immune factors in endometriosis-related conditions

10. Pain

11. Immune Phenotypes and Mediators Affecting Endometrial Function in Women with Endometriosis

12. Ovarian Dysfunction

13. The role of immune-related redox biology in Malignant Transformation of endometriosis

14. Pregnancy complications

Section 3 - Immunology and the management of endometriosis

15. Immunology and novel therapeutic strategy of endometriosis

16. Anti-inflammatory reagents : the role of NF-κB

17. Gut Microbiota

18. Immunosuppression and immunotherapy: pathophysiology, recent development and future perspectives


Immunology of Endometriosis: Etiology and Management, a volume in the Reproductive Immunology series, provides updates on one of most common gynecological diseases, including basic science concepts and their clinical applications related to endometriosis immunology. Various immunological factors are believed to play roles in the pathogenesis of endometriosis, providing potential targets for the disease. Endometriosis is now considered to be a disease of both endocrine and immune dysregulation. However, recognition of the direct involvement of two major physiological mechanisms brings about a change of focus which might represent an interesting advance in the understanding of this disease and new focus for further research.

Key Features

  • Provides detailed immunological background to help readers understand etiology and management of endometriosis
  • Evaluates various immunological factors that are involved in the pathogenesis of endometriosis
  • Presents a detailed evaluation of the knowledge related to each immune cell type in endometriosis


Medical and research. Researchers, Clinicians and trainees working in the field of endometriosis


No. of pages:
© Academic Press 2021
26th November 2021
Academic Press
Paperback ISBN:

Ratings and Reviews

About the Editor

Kaori Koga

Kaori Koga, M.D., Ph.D. is a physician-scientist and an Associate Professor of the Department of Obstetrics and Gynecology, School of Medicine at the University of Tokyo, Japan. Dr. Koga received her M.D. degree from Chiba University, Chiba, Japan, and her Ph.D. degree from the University of Tokyo. She undertook post-doctoral fellowships in the Uterine Biology Group (Prof. Lois Salamonsen’s laboratory) at Prince Henry’s Institute, Melbourne, Australia in 2006, and the Reproductive Immunology Unit (Prof. Gil Mor’s laboratory) at the Department of Obstetrics, Gynecology and Reproductive Sciences in Yale University in 2006–2008. Dr. Koga's keen interest lies in Reproductive Immunology, with particular focus on endometriosis and infertility. As a gynecological clinician, Dr. Koga has treated many patients with endometriosis and has performed Minimally Invasive Surgery and Aassisted Reproductive Technology. Dr. Koga has received numerous national and international awards, including Kanzawa Award from the Kanzawa Medical Research Foundation in 2018 and Guston Award from the American Society for Reproductive Immunology (ASRI) in 2008. She is a member of the ASRI, the International Society for Immunology of Reproduction (ISIR) as well as of the European Society of Human Reproduction and Embryology (ESHRE), and an ambassador of the World Endometriosis Society (WES). Dr Koga is an Associate Editor of Human Reproduction Open (2021–) and serves on the editorial boards of the American Journal of Reproductive Immunology, and the Journal of Reproductive Immunology.

Affiliations and Expertise

Associate Professor of the Department of Obstetrics and Gynecology, School of Medicine at the University of Tokyo, Japan