Hyphenations of Capillary Chromatography with Mass Spectrometry

Hyphenations of Capillary Chromatography with Mass Spectrometry provides comprehensive coverage of capillary chromatography with mass spectrometry—both single and multidimensional approaches. The book examines nearly all capillary chromatography approaches, combined with a variety of MS forms, giving readers a wide and detailed view on current-day analytical strategies and applications. Of particular focus are novel developments in the field of MS, such as the Orbitrap, HR ToF, ToF MS with variable electron-impact energy, fast MS-MS and APGC technology.

Junior scientists conducting research on mono-dimensional chromatography-MS fundamental relationships and experienced analytical chemists working in conventional capillary chromatography and classical multidimensional chromatography will find this an ideal application-based reference on the hyphenations of these domains.

• Combines mass spectrometry with a range of chromatographic approaches
• Emphasizes the importance of both capillary chromatography and mass spectrometry methods, thus stimulating separation scientists to fully exploit both analytical dimensions
• Authored by two of the world’s leading analytical chemists who have a total of more than 40 years of experience in research and instruction

Analytical chemists operating in multidimensional, comprehensive, and conventional capillary chromatography

1. Introduction
   2. Hyphenation of gas chromatography with mass spectrometry: history, general principles and theoretical aspects
   3. Gas chromatography-mass spectrometry
   3.1. Hyphenations of 1D GC with mass spectrometry
   3.1.1. Conventional GC
   3.1.2. Fast GC
   3.2. Hyphenations of 2D GC with mass spectrometry
   3.2.1. Classical 2D GC
   3.2.2. Comprehensive 2D GC
   4. Hyphenation of capillary liquid chromatography with mass spectrometry: history, general principles and theoretical aspects
   5. Capillary liquid chromatography-mass spectrometry
   5.1. Hyphenations of 1D capillary LC with mass spectrometry
   5.2. Hyphenations of 2D capillary LC with mass spectrometry
   6. Capillary supercritical fluid chromatography-mass spectrometry
   6.1 History, general principles and theoretical aspects
   6.2 Hyphenations of 1D and 2D capillary SFC with mass spectrometry
   7. Capillary electrophoresis-mass spectrometry
   7.1 History, general principles and theoretical aspects
   7.2 Hyphenations of 1D and 2D CE with mass spectrometry
   8. Hyphenation of mixed-mode multidimensional chromatography with mass spectrometry
   5.1. LC-GC
   5.2. SFC-GC
   5.3. LC-CE
   5.4. LC-SFC