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Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy - 1st Edition - ISBN: 9780128222690

Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy, Volume 3

1st Edition

Editor: Peder Larson
Paperback ISBN: 9780128222690
Imprint: Academic Press
Published Date: 1st November 2021
Page Count: 325
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Table of Contents

1. DNP Physics
2. DNP Hardware
3. HP Acquisition Methods
4. HP Experimental Methods
5. HP Agents and Biochemical Interactions
6. HP Data Analysis and Visualization
7. Integration into Cancer Studies
8. Integration into Neurological Studies
9. Integration into Cardiac Studies
10. Integration into Liver Studies


MRI with hyperpolarized carbon-13 agents is a powerful emerging imaging modality that can measure real-time metabolism in cells, animals, and humans. It uses endogenous, non-toxic contrast agents that a hyperpolarized, resulting in up to 100,000-fold increases in sensitivity. This technique uses no ionizing radiation, and is being applied in a range of human trials. It’s primary use is for metabolic imaging, but it can also measure perfusion, pH, and necrosis.

Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy is designed to be a one stop shop for understanding hyperpolarized 13C MRI. This book explains the principles of this imaging modality, the requirements for performing studies, shows how to interpret the results, and gives an overview of current biomedical applications. It is suitable for engineers, scientists and clinicians in radiology and biomedical imaging who want to understand this technology.

Key Features

  • Presents the physics and hardware of dissolution dynamic nuclear polarization
  • Explains the behaviour of hyperpolarized carbon-13 agents and how to image them
  • Detailed guidance on experimental design and data interpretation
  • Identifies promising and potential applications of hyperpolarized carbon-13 MR


Researchers and graduate students in MRI, clinicians and clinical researchers


No. of pages:
© Academic Press 2021
1st November 2021
Academic Press
Paperback ISBN:

Ratings and Reviews

About the Editor

Peder Larson

Peder Larson, PhD, is an Associate Professor in Residence and a Principal Investigator in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Larson's research program is primarily centered around developing new MRI scanning and reconstruction technology for improved clinical outcomes Dr. Peder Larson got his PhD under Dwight Nishimura from the Department of Electrical Engineering at Stanford University on "MRI of Semi-solid Tissues" in 2007. His research interests are in RF pulse design, pulse sequence development, novel imaging strategies, and optimized reconstruction methods for MRI, with an emphasis on applications in Hyperpolarized carbon-13 agents and semi-solid tissue imaging with ultrashort echo time (UTE) methods.

Affiliations and Expertise

Associate Professor in Residence and Principal Investigator, Department of Radiology and Biomedical Imaging, University of California, San Francisco, USA