Human Papillomavirus Infections

1st Edition

From the Laboratory to Clinical Practice

Print ISBN: 9781907568749
eBook ISBN: 9781908818171
Imprint: Woodhead Publishing
Published Date: 27th July 2012
Page Count: 168
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Human papillomavirus (HPV) is one of the most common causes of sexually transmitted diseases worldwide, both in men and women. Human papillomavirus infections provides the scientific background needed to understand the natural history and pathogenesis of HPV infection and offers discussion of its clinical features, diagnosis, treatment and prevention. The book begins with chapters covering the epidemiology, virology, history and transmission of the infection, as well as its pathogenesis and clinical features. Following a discussion of the relationship between HPV and cancer, chapters in the second half of the book look at diagnosis, testing and treatment. The book concludes with detailed coverage of the prevention of HPV through worldwide vaccination programmes.

Key Features

  • Covers all the important issues relating to both male and female HPV infection
  • Provides overview of the current knowledge about epidemiology, basic virology, pathogenesis and diagnosis methods
  • Explores the relationship between HPV and cancer


Practitioners: microbiologists, pathologists, infectologists, gynecologist, primary health care physician, primary health care nurses and epidemiologists; Researchers and laboratory workers

Table of Contents

List of figures and tables

List of abbreviations


About the author

Chapter 1: Introduction and epidemiological data


1.1 Data about general epidemiology

1.2 HPV types and their relationship with human diseases

1.3 Epidemiology of HPV in men

Chapter 2: Basic virology: structure and nomenclature


2.1 HPV nomenclature

2.2 HPV structure

2.3 Classification: types, subtypes and variants

2.4 Function of viral proteins

Chapter 3: Natural history and transmission: anatomic distribution


3.1 Methods of transmission of HPV infections

3.2 Natural history of HPV infection

Chapter 4: Pathogenesis and clinical features


4.1 Pathogenesis

4.2 Clinical features

Chapter 5: HPV infection and association with cancer


5.1 The relationship between HPV and cancer

Chapter 6: Diagnosis of HPV infection


6.1 Methods of specimen collection

6.2 Conventional and monolayer cytology

6.3 Histopathology

6.4 HPV nucleic acid detection

6.5 Serological assays

6.6 Diagnostic utility of P16INK4a

6.7 Evaluation of DNA testing and HPV mRNA with liquid-based cytology

Chapter 7: Clinical utility of HPV testing


7.1 Screening programmes for cervical cancer diagnosis

7.2 Strategies for the management of HPV infection and risk of cancer

Chapter 8: Treatment


8.1 Treatment of benign lesions

8.2 Treatment of precancerous lesions

8.3 Treatment of cancer

Chapter 9: Prevention: HPV vaccines


9.1 HPV vaccine types

9.2 Recommendations for the use of HPV vaccines

9.3 HPV vaccine acceptance and licensure status

9.4 Areas for research in HPV vac


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© Woodhead Publishing 2012
Woodhead Publishing
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This succinct review of the various facets of HPV invection and disease will be very useful for the intended audiences interested in this subject...There are no comparable books., Doody's Reviews