This publication on HHV-6 is the first and so far only one where a composite picture of the virus is presented. Comprehensive accounts of HHV-6 biology, molecular virology, epidemiology and their association with diseases, including the effects of antiviral drugs, are covered in chapters contributed by leading researchers on HHV-6. The book is an excellent source of reference on HHV-6 for basic researchers, diagnostic virologists, clinicians, medical students and medical librarians since it provides the most current state-of-the-art information on HHV-6.

Table of Contents

Editors' foreword. Preface. List of Contributors. Part I. General Virology. Chapter 1. Aids and the discovery of human herpesvirus type 6 [HHV-6] (S.Z. Salahuddin). 2. The epidemiology of HHV-6 (P.H. Levine, R. Jarrett and D.A. Clark). 3. Target cells for infection (P. Lusso). 4. In vitro propagation systems for HHV-6 (D.V. Ablashi and C.L. Hung). 5. Infection, latency and immortalization of human cells with HHV-6 (J. Luka). 6. Electron microscopy of HHV-6 (B. Kramarsky and Ch. Sander). 7. Biology and strain variants (D.V. Ablashi and S.Z. Salahuddin). 8. Molecular biology of HHV-6 (Z.N. Berneman and D.V. Ablashi). 9. Proteins of HHV-6 (N. Balachandran). 10. Interactions between HHV-6 and other viruses (P. Lusso, D.V. Ablashi and J. Luka). Part II. Clinical Pathology. 11. HHV-6 and exanthem subitum (H. Kikuta). 12. Exanthem subitum and HHV-6 infection (K. Yamanishi, T. Okuno, K. Takahashi, K. Balanchandra, K. Kondo, T. Kondo and T. Mukai). 13. HHV-6-induced mononucleosis-like illnesses (C.A. Horwitz, G.R.F. Krueger, T.A. Steeper and G. Bertram). 14. Kikuchi's disease [histiocytic necrotizing lymphadenitis] (M. Kikuchi, Y. Sumiyoshi and Y. Minamishima). 15. HHV-6 in atypical polyclonal lymphoproliferation [APL] and malignant lymphomas (G.R.F. Krueger, D.V. Ablashi, S.F. Josephs and N. Balanchandran). 16. Detection of HHV-6 genomes in lymphoproliferative diseases (K. Ellinger, F. Neipel, S. Seidl, B. Borisch-Chappuis, K. Müller-Hermelink and B. Fleckenstein). 17. Detection of HHV-6 using polymerase chain reaction amplification (R. Jarrett and M.E. Klotman). 18. `Post-Viral' chronic fatigue syndrome (A.L. Komaroff, G. Gupta and I.E. Salit). 19. HHV-6 and HIV-1 infection (M.H. Kaplan). 20. HIV-1 and HHV-6 infections of human retina and cornea (H.B. Qavi, M.T. Green and G.K. SeGall). 21. HHV-6 and bone marrow transplantation (D.R. Carrigan). 22. HHV-6 in Sjögren's syndrome (L.S. De Clerck, N. Bourgeois, G.R.F. Krueger


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© 1992
Elsevier Science
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About the editors

Dharam Ablashi

Affiliations and Expertise

Scientific Director, HHV-6 Foundation & Adjunct Professor Microbiology, HHV-6 Foundatiton, Santa Barbara, CA, U.S.A.

G.R.F. Krueger

Affiliations and Expertise

University of Texas, HSC at Houston, Houston, TX, USA

S.Z. Salahuddin

Affiliations and Expertise

University of Southern California, Los Angeles, CA, USA


@qu:...a valuable reference for epidemiologists, pathologists, clinicians, scientists entering the field of herpesvirus research, and medical and microbiology students @source:Biological Abstracts @qu:...a worthwhile addition to the collections of medical libraries and specialists in the field. @source:Virus Research @qu:...I would recommend it as a suitable introduction for an investigator working with this specific virus. @source:Society for General Microbiology Quarterly