Human Gene Evolution - 1st Edition - ISBN: 9780121878702, 9780080917467

Human Gene Evolution

1st Edition

Series Volume Editors: Stephen Cooper
eBook ISBN: 9780080917467
Hardcover ISBN: 9780121878702
Imprint: Academic Press
Published Date: 3rd November 1999
Page Count: 500
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Table of Contents

Preface. Abbreviations.

Introduction and Overview: Structure and Function in the Human Genome. Evolution of the Human Genome.

Evolution of Gene Structure: Introns, Exons and Evolution. Genes and Gene Families. Promoters and Transcription Factors. Pseudogenes and their Formation.

Mutational Mechanisms in Evolution: Single Base-pair Substitutions. Contractions and Expansions in Gene Size and Number. Gross Gene Rearrangements. Molecular Reconstruction of Ancient Genes/Proteins. Indices of Human Gene Symbols used in the text. Index.


Presents the principles of human gene evolution in a concise and easy to understand fashion. Uses examples of how evolutionary processes have molded present day genes, drawn from the evolution of humans and other primates, as well as from more primitive organisms. With increasing attention in this expanding area, this review forms a timely publication of our current knowledge of this important field.

Key Features

  • Structure and function in the human genome
  • The evolution of gene structure
  • Mutational mechanisms in evolution


Molecular Biologists, Geneticists


No. of pages:
© Academic Press 2000
Academic Press
eBook ISBN:
Hardcover ISBN:


"Professor Cooper has given us a comprehensive, authoritative, fascinating and masterful account of the evolutionary history of the human genes. Human Gene Evolution is recommended for the novice and the experienced alike." --Professor Stylianos Antonarakis

Ratings and Reviews

About the Series Volume Editors

Stephen Cooper Series Volume Editor

Affiliations and Expertise

University of Michigan Medical School