Human Anti-Human Gammaglobulins, Their Specificity and Function

Proceedings of the International Symposium Held in Lund, October 1969

1st Edition - January 1, 1971
Editors: R. Grubb, G. Samuelsson
Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 1 - 5 9 8 3 - 6

Human Anti-Human Gammaglobulins: Their Specificity and Functions is a written record of the seventeenth volume of the Wenner-Gren International Symposium Series, which aims to… Read more

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Human Anti-Human Gammaglobulins: Their Specificity and Functions is a written record of the seventeenth volume of the Wenner-Gren International Symposium Series, which aims to define natural mechanisms giving rise to human anti-immunoglobulins, the interactions between anti-Igs and Ig determinants and its effects. The book is divided according to the six sessions that were held during the symposium. Topics include basic experimental data; determinants of IgG revealed by human antiglobulins; anti-gammaglobulin factors in tissues; anti-gammaglobulins interacting with immunoglobulins in solution; anti-gammaglobulin—cellular interactions; and a special lecture. The text is recommended for medical doctors, especially immunologists, who want to know more about the human anti-human gammaglobulin, its origin, functions, and the discoveries about it.

Preface

List of Participants

Aime of the Symposium

Session 1 Basic Experimental Data

Gene Interactions in Immunoglobulins

Discussion

Observations and Reflections on Idiotypy of Rabbit Antibodies and Its Possible Relationship to Antibody Function

Discussion

Human Anti-human Globulin with Idiotypic Specificities

Discussion

Stability of Gm Polymorphism

Discussion

Allotypic Suppression in Rabbits: Operational Definition of the Target Cells

Discussion

Quantitative Studies on Antiglobulin Factors in Rheumatoid Arthritis and Allied Disorders

Discussion

Session 2 Determinants of IgG Revealed by Human Antiglobulins

Experimental Anti-γG-globulins in Infectious Diseases

Discussion

Some Antigenic Determinants Characteristic of Native and Aggregated Human IgG

Discussion

The Reaction of Rheumatoid Factor with Immunoglobuhn G from Various Animal Species

Serological Studies of Enzymatically Fragmented IgG Globulins

Discussion

Session 3 Anti-gammaglobulin Factors in Tissues

Some Aspects of the Occurrence of Immune Globulins in Tissue Lesions, Bound Anti-γ-globulin Activity in Leprosy and Tuberculosis

Discussion

Immunological Studies on Eluates from Rheumatoid Inflammatory Tissue

IgG-anti-IgG Factors and IgG-ß1c Complexes in Rheumatoid Synovial Tissue

Discussion

Nature and Specificity of Anti-γ-globulin Factors in Tissue

Discussion

Total Complement, Concentration and Conversion of the Third Component of Complement in Synovial Fluid from Arthritic Patients. Associations with Seropositivity

Discussion

Session 4 Anti-gammaglobulins Interacting with Immunoglobulins in Solution

Human Antibodies to Human IgA: A Clinical, Serologic and Immunogenetic Study

Discussion

Human Antibodies to γAl and γA2 Globulins; Detection of a γA2 Genetic Marker

Discussion of Papers

The Transient Nature of Anti-Gm

Discussion

Immunological Studies of Mixed Cryoimmunoglobulinemia

Discussion

Clinical and Immunochemical Observations in Cryoglobulinemia with Special Reference to IgM Heterogeneity

Discussion

A Clinical Syndrome with Circulating Gammaglobulin Complexes ("Intermediate Complexes")

Discussion

Session 5 Anti-gammaglobulin—Cellular Interactions

Immunoglobulin Determinants on Lymphocytes

Discussion

Inhibition of Antigen-induced Lymphocyte Transformation by Anti-immunoglobulin Light-chain Sera

Discussion

Stimulation of Human Lymphocytes In Vitro by Anti-F(ab')2 Antisera

Inhibition of Lymphocyte-mediated Cytotoxicity by Antisera to Immunoglobulins

Discussion

Effect of Human Pepsin-site Agglutinators on In Vitro Phagocytosis

Discussion

Session 6 Special Lecture

Foetomaternal Histoincompatibility in Toxaemia of Pregnancy