Huether and McCance's Understanding Pathophysiology, Canadian Edition

2nd Edition - January 8, 2022
Authors: Kelly Power-Kean, Stephanie Zettel, Mohamed Toufic El-Hussein, Sue E. Huether, Kathryn L. McCance
Language: English
Other ISBN:
9 7 8 - 0 - 3 2 3 - 8 8 1 9 2 - 0
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 7 7 8 8 4 - 8

Prepare for Canadian nursing practice with a solid understanding of pathophysiology and disease! Huether and McCance's Understanding Pathophysiology, 2nd Canadian Edition cover… Read more

Huether and McCance's Understanding Pathophysiology, Canadian Edition

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Prepare for Canadian nursing practice with a solid understanding of pathophysiology and disease! Huether and McCance's Understanding Pathophysiology, 2nd Canadian Edition covers the basic concepts of pathophysiology and disease processes from a Canadian perspective. Clear descriptions and vibrant illustrations make it easier to understand body systems and the mechanisms of disease, and online resources bring pathophysiology concepts to life. Developed for Canadian nursing students by educators Kelly Power-Kean, Stephanie Zettel, and Mohamed Toufic El-Hussein, this text prepares students for success on the Next Generation NCLEX®, CPNRE®, and REx-PN™ and also in clinical practice.

Cover image
Title page
Table of Contents
Evolve Student Resources
Health Promotion Boxes
Copyright
Reviewers
Contributors
Preface
Organization and Content
Features to Promote Learning
Art Program
Teaching/Learning Package
Next Generation NCLEX (NGN)
Acknowledgements
Introduction to Pathophysiology
Part One: Basic Concepts of Pathophysiology
Unit 1: The Cell
1. Cellular Biology
Chapter Outline
Key Terms
Prokaryotes and Eukaryotes
Cellular Functions
Structure and Function of Cellular Components
Cell-To-Cell Adhesions
Cellular Communication and Signal Transduction
Cellular Metabolism
Membrane Transport: Cellular Intake and Output
Cellular Reproduction: The Cell Cycle
Tissues
Did You Understand?
References (Chapter 1)
2. Genes and Genetic Diseases
Chapter Outline
Key Terms
DNA, RNA, and Proteins: Heredity at the Molecular Level
Chromosomes
Elements of Formal Genetics
Transmission of Genetic Diseases
Linkage Analysis and Gene Mapping
Multifactorial Inheritance
Did You Understand?
References (Chapter 2)
3. Epigenetics and Disease
Chapter Outline
Key Terms
Epigenetic Mechanisms
Epigenetics and Human Development
Genomic Imprinting
Inheritance of Epigenetic States
Epigenetics and Ethanol Exposure During GESTATION
Epigenetics and Cancer
Future Directions
Did You Understand?
References (Chapter 3)
4. Altered Cellular and Tissue Biology
Chapter Outline
Key Terms
Cellular Adaptation
Cellular Injury
Manifestations of Cellular Injury: Accumulations
Cellular Death
Aging and Altered Cellular and Tissue Biology
Somatic Death
Did You Understand?
References (Chapter 4)
5. Fluids and Electrolytes, Acids and Bases
Chapter Outline
Key Terms
Distribution of Body Fluids and Electrolytes
Alterations in Water Movement
Sodium, Chloride, and Water Balance
Alterations in Sodium, Chloride, and Water Balance
Alterations in Potassium and Other Electrolytes
Acid–Base Balance
Did You Understand?
References (chapter 5)
Unit 2: Mechanisms of Self-Defence
6. Innate Immunity: Inflammation and Wound Healing
Chapter Outline
Key Terms
Human Defence Mechanisms
Acute and Chronic Inflammation
Wound Healing
Did You Understand?
References (Chapter 6)
7. Adaptive Immunity
Chapter Outline
Key Terms
Third Line of Defence: Adaptive Immunity
Antigens and Immunogens
Antibodies
Immune Response: Collaboration of B Cells and T Cells
Cell-Mediated Immunity
Did You Understand?
References (Chapter 7)
8. Infection and Defects in Mechanisms of Defence
Chapter Outline
Key Terms
Infection
Deficiencies in Immunity
Hypersensitivity: Allergy, Autoimmunity, and Alloimmunity
Did You Understand?
References (Chapter 8)
9. Stress and Disease
Chapter Outline
Key Terms
Historical Background and General Concepts
The Stress Response
Stress, Personality, Coping, and Illness
Did You Understand?
References (Chapter 9)
Unit 3: Cellular Proliferation: Cancer
10. Biology of Cancer
Chapter Outline
Key Terms
Cancer Terminology and Characteristics
The Biology of Cancer Cells
Clinical Manifestations of Cancer
Diagnosis, Characterization, and Treatment of Cancer
Did you understand?
References (Chapter 10)
11. Cancer Epidemiology
Chapter Outline
Key Terms
Genetics, Epigenetics, and Tissue
Incidence and Mortality Trends
In Utero and Early Life Conditions
Environmental and Lifestyle Factors
Did You Understand?
References (Chapter 11)
12. Cancer in Children and Adolescents
Chapter Outline
Key Terms
Incidence, Etiology, and Types of Childhood Cancer
Prognosis
Did You Understand?
References (Chapter 12)
Part Two: Body Systems and Diseases
Unit 4: The Neurological System
13. Structure and Function of the Neurological System
Chapter Outline
Key Terms
Overview and Organization of the Nervous System
Cells of the Nervous System
The Nerve Impulse
The Central Nervous System
The Peripheral Nervous System
The Autonomic Nervous System
Did You Understand?
References (Chapter 13)
14. Pain, Temperature, Sleep, and Sensory Function
Chapter Outline
Key Terms
Pain
Temperature Regulation
Sleep
The Special Senses
Somatosensory Function
Did You Understand?
References (Chapter 14)
15. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
Chapter Outline
Key Terms
Alterations in Cognitive Systems
Alterations in Cerebral Hemodynamics
Alterations in Neuromotor Function
Alterations in Complex Motor Performance
Extrapyramidal Motor Syndromes
Did You Understand?
References (Chapter 15)
16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction
Chapter Outline
Key Terms
Central Nervous System Disorders
Peripheral Nervous System and Neuromuscular Junction Disorders
Tumours of the Central Nervous System
Did You Understand?
References (Chapter 16)
17. Developmental Alterations of Neurological Function
Chapter Outline
Key Terms
Development of the Nervous System in Children
Structural Malformations
Alterations In Function: Encephalopathies
Cerebrovascular Disease in Children
Childhood Tumours
Did You Understand?
References (Chapter 17)
Unit 5: The Endocrine System
18. Mechanisms of Hormonal Regulation
Chapter Outline
Key Terms
Mechanisms of Hormonal Regulation
Structure and Function of the Endocrine Glands
Did You Understand?
References (Chapter 18)
19. Alterations of Hormonal Regulation
Chapter Outline
Key Terms
Mechanisms of Hormonal Alterations
Alterations of the Hypothalamic-Pituitary System
Alterations of Thyroid Function
Alterations of Parathyroid Function
Dysfunction of the Endocrine Pancreas: Diabetes Mellitus
Alterations of Adrenal Function
Did You Understand?
References (Chapter 19)
Unit 6: The Hematological System
20. Structure and Function of the Hematological System
Chapter Outline
Key Terms
Components of the Hematological System
Development of Blood Cells
Mechanisms of Hemostasis
Did You Understand?
References (Chapter 20)
21. Alterations of Hematological Function
Chapter Outline
Key Terms
Alterations of Erythrocyte Function
Myeloproliferative Red Blood Cell Disorders
Alterations of Leukocyte Function
Alterations of Lymphoid Function
Alterations of Splenic Function
Hemorrhagic Disorders and Alterations of Platelets and Coagulation
Did You Understand?
References (Chapter 21)
22. Developmental Alterations of Hematological Function
Chapter Outline
Key Terms
Disorders of Erythrocytes
Disorders of Coagulation and Platelets
Neoplastic Disorders
Did You Understand?
References (Chapter 22)
Unit 7: The Cardiovascular and Lymphatic Systems
23. Structure and Function of the Cardiovascular and Lymphatic Systems
Chapter Outline
Key Terms
The Circulatory System
The Heart
The Systemic Circulation
The Lymphatic System
Did You Understand?
References (Chapter 23)
24. Alterations of Cardiovascular Function
Chapter Outline
Key Terms
Diseases of the Veins
Diseases of the Arteries
Disorders of the Heart Wall
Manifestations of Heart Disease
Shock
Did You Understand?
References (Chapter 24)
25. Developmental Alterations of Cardiovascular Function
Chapter Outline
Key Terms
Congenital Heart Disease
Acquired Cardiovascular Disorders
Did You Understand?
References (Chapter 25)
Unit 8: The Pulmonary System
26. Structure and Function of the Pulmonary System
Chapter Outline
Key Terms
Structures of the Pulmonary System
Function of the Pulmonary System
Did You Understand?
References (Chapter 26)
27. Alterations of Pulmonary Function
Chapter Outline
Key Terms
Clinical Manifestations of Pulmonary Alterations
Disorders of the Chest Wall and Pleura
Pulmonary Disorders
Did You Understand?
References (Chapter 27)
28. Developmental Alterations of Pulmonary Function
Chapter Outline
Key Terms
Disorders of the Upper Airways
Disorders of the Lower Airways
Sudden Unexpected Infant Death
Did You Understand?
References (Chapter 28)
Unit 9: The Renal and Urological Systems
29. Structure and Function of the Renal and Urological Systems
Chapter Outline
Key Terms
Structures of the Renal System
Urinary Structures
Renal Blood Flow
Kidney Function
Tests of Renal Function
Did You Understand?
References (Chapter 29)
30. Alterations of Renal and Urinary Tract Function
Chapter Outline
Key Terms
Urinary Tract Obstruction
Urinary Tract Infection
Glomerular Disorders
Acute Kidney Injury
Chronic Kidney Disease
Did you understand?
References (Chapter 30)
31. Developmental Alterations of Renal and Urinary Tract Function
Chapter Outline
Key Terms
Structural Abnormalities
Glomerular Disorders
Nephroblastoma
Bladder Disorders
Urinary Incontinence
Did You Understand?
References (Chapter 31)
Unit 10: The Reproductive Systems
32. Structure and Function of the Reproductive Systems
Chapter Outline
Key Terms
Development of the Reproductive Systems
The Female Reproductive System
Structure and Function of the Breast
The Male Reproductive System
Aging and Reproductive Function
Did You Understand?
References (Chapter 32)
33. Alterations of the Female Reproductive System
Chapter Outline
Key Terms
Abnormalities of the Female Reproductive Tract
Alterations of Sexual Maturation
Disorders of the Female Reproductive System
Disorders of the Female Breast
Did You Understand?
References (Chapter 33)
34. Alterations of the Male Reproductive System
Chapter Outline
Key Terms
Alterations of Sexual Maturation
Disorders of the Male Reproductive System
Disorders of the Male Breast
Sexually Transmitted Infections
Did You Understand?
References (Chapter 34)
Unit 11: The Digestive System
35. Structure and Function of the Digestive System
Chapter Outline
Key Terms
The Gastro-Intestinal Tract
Accessory Organs of Digestion
Did you understand?
References (Chapter 35)
36. Alterations of Digestive Function
Chapter Outline
Key Terms
Disorders of the Gastro-Intestinal Tract
Disorders of the Accessory Organs of Digestion
Cancer of the Digestive System
Did You Understand?
References (Chapter 36)
37. Developmental Alterations of Digestive Function
Chapter Outline
Key Terms
Disorders of the Gastro-Intestinal Tract
Disorders of the Liver
Gastro-Intestinal Malignancies in Children
Did you understand?
References (Chapter 37)
Unit 12: The Musculoskeletal and Integumentary Systems
38. Structure and Function of the Musculoskeletal System
Chapter Outline
Key Terms
Structure and Function of Bones
Structure and Function of Joints
Structure and Function of Skeletal Muscles
Aging and the Musculoskeletal System
Did you understand?
References (Chapter 38)
39. Alterations of Musculoskeletal Function
Chapter Outline
Key Terms
Musculoskeletal Injuries
Disorders of Bones
Disorders of Joints
Disorders of Skeletal Muscle
Musculoskeletal Tumours
Did you understand?
References (Chapter 39)
40. Developmental Alterations of Musculoskeletal Function
Chapter Outline
Key Terms
Congenital Defects
Bone Infection
Juvenile Idiopathic Arthritis
Osteochondroses
Scoliosis
Muscular Dystrophy
Musculoskeletal Tumours
Nonaccidental Trauma
Did you understand?
References (Chapter 40)
41. Structure, Function, and Disorders of the Integument
Chapter Outline
Key Terms
Structure and Function of the Skin
Disorders of the Skin
Disorders of the Hair
Disorders of the Nail
Did you understand?
References (Chapter 41)
42. Developmental Alterations of the Integument
Chapter Outline
Key Terms
Acne Vulgaris
Dermatitis
Infections of the Skin
Insect Bites and Parasites
Cutaneous Hemangiomas and Vascular Malformations
Other Skin Disorders
Did you understand?
References (Chapter 42)
Appendix
Laboratory Values
Index
Prefixes and Suffixes used in Medical Terminology
Word Roots Commonly used in Medical Terminology

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Limited Offer

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Immediately download your ebook while waiting for your print delivery. No promo code is needed.

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Kelly Power-Kean

Stephanie Zettel

Mohamed Toufic El-Hussein

Sue E. Huether

Kathryn L. McCance