How Sex and Gender Impact Clinical Practice

How Sex and Gender Impact Clinical Practice

An Evidence-Based Guide to Patient Care

1st Edition - December 1, 2020

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  • Editors: Marjorie Jenkins, Connie Newman
  • Paperback ISBN: 9780128165690
  • eBook ISBN: 9780128167502

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How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease.

Key Features

  • Explores the effects of sex and gender on disease presentation, treatment and prognosis, and how these differences influence clinical decision-making
  • Provides practical guidance that helps clinicians implement a more individualized approach to patient care
  • Contains information on diseases in each major specialty, as well as chapters on communication, pharmacology and public health challenges


Biomedical researchers in endocrinology, cardiology, neuroscience, and development biology; medical students, residents, and practicing primary care clinicians as well as PAs and NPs.

Table of Contents

  • Foreword
    Maryanne Legato
    Connie Newman and Marjorie R. Jenkins

    Section I: The Importance of Sex and Gender in Patient Care
    1. Application of Sex and Gender Health: A Practical Framework
    Marjorie R. Jenkins and Catherine A. Johnson
    2. Clinician-Patient Communication: Gender Influences
    Amy Koerber and Kaye Renshaw

    Section II: Sex and Gender Evidence in Health and Disease
    3. Addiction: Sex and Gender Evidence in Alcohol, Tobacco, and Opioids Substance Use Disorders
    Mishka Terplan, Caitlin Martin and Anna Scialli
    4. Autoimmune Diseases: Sex and Gender Evidence in Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Ankylosing Spondylitis
    Kristen Demoruelle and Emily Bowers
    5. Cancer Screening and Prevention: Sex and Gender Evidence in Lung, Breast, and Colorectal Cancer 
    Rashmi Verma and Manojna Konda
    6. Cardiovascular Disease: Sex and Gender Evidence in Acute Ischemic Syndrome and Heart Failure
    Basmah Safdar
    7. Gastrointestinal Diseases: Sex and Gender Evidence in Liver Lesions, Gastroesophageal Reflux, and Inflammatory Bowel Disease
    Dina Halegoua-De Marzio and Sanaa Arastu
    8. Mental Health: Sex and Gender Evidence in Schizophrenia, Depression, and Anxiety Disorders
    Susan Kornstein and Bushra Shah
    9. Metabolic Disorders: Sex and Gender Evidence in Dyslipidemia, Diabetes, and Obesity
    Connie Newman, Katherine Saunders and Savitha Subramanian
    10. Musculoskeletal Disorders: Sex and Gender Evidence in ACL Injuries, Osteoarthritis, and Osteoporosis
    Kimberly Templeton
    11. Neurological Diseases: Sex and Gender Evidence in Stroke, Migraine, and Alzheimer’s Dementia
    Neelum Aggarwal
    12. Pharmacology: Sex and Gender Evidence in Medication Safety and Efficacy
    Rebecca Sleeper and Dr. Cox
    13. Public Health in Your Practice: Sex and Gender Considerations in Access to Healthcare, Immunizations, and Intimate Partner Violence
    Theresa Byrd and Rubini Pasupathy
    14. Respiratory Diseases: Sex and Gender Evidence in Obstructive Sleep Apnea, COPD, and Asthma
    Juliana Kling and Kathyrn Williams

    Section III: Beyond Point of Care: Sex and Gender Influences in the Community of Practice
    15. The Business of Medicine: Making the Case for a Sex and Gender Practice
    Marjorie R. Jenkins
    16. Knowledge Resources in Sex and Gender Health
    Janice L. Werbinski

Product details

  • No. of pages: 360
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: December 1, 2020
  • Imprint: Academic Press
  • Paperback ISBN: 9780128165690
  • eBook ISBN: 9780128167502

About the Editors

Marjorie Jenkins

Dr. Jenkins serves as the Dean at the School of Medicine Greenville, Associate Provost University of South Carolina, and Chief Academic Officer for Prisma Health Upstate. She has served many additional leadership roles such as Director of Medical Initiatives and Scientific Engagement at the U.S. Food and Drug Administration Office of Women’s Health (OWH); Graduate Research Program Director, Master of Education for Health Professions at Johns Hopkins University, College of Education, Professor of Internal Medicine, and Founding Director and Chief Scientific Officer for the Laura W. Bush Institute at Texas Tech University Health Sciences Center; She is a founder and past co-chair of the National Sex and Gender in Health Professions Education Summit. She is nationally and internationally known in the area of sex and gender-specific clinical care, research application, and health professions curriculum development.

Affiliations and Expertise

Dean at the School of Medicine Greenville, Associate Provost University of South Carolina, and Chief Academic Officer for Prisma Health Upstate.

Connie Newman

Adjunct Professor of Medicine at the New York University Grossman School of Medicine, is Board Certified in Internal Medicine, Endocrinology and Metabolism, and Obesity Medicine. She is a Fellow of the American College of Physicians, the American Heart Association, the American Medical Women’s Association (AMWA), and the New York Academy of Medicine. She served as the 2018-2019 President of AMWA, an organization of women physicians, pre-medical and medical students that advocates for advancement of women in medicine, health equity and sex and gender based medical education. Dr. Newman is recognized for her expertise in hypercholesterolemia, hypertriglyceridemia, statin safety, and randomized controlled clinical trials. She is the Chair of the 2020 Endocrine Society clinical practice guideline on the management of dyslipidemia in endocrine diseases, and served as Chair of the writing group for the American Heart Association’s 2019 Scientific Statement on the safety of statins. Dr. Newman is an appointed member of the FDA Endocrine and Metabolic Disorders Advisory Committee. Dr. Newman writes and speaks on the topics of sex and gender health, high cholesterol and heart disease, and statin safety. She is the recipient of the 2020 Bertha Van Hoosen Award, named for the founder of AMWA. She is featured in “20 Women, 20 Years”, an online exhibit of leaders in the medical profession, sponsored by the Women in Medicine Legacy Foundation.

Affiliations and Expertise

Adjunct Professor of Medicine, Division of Endocrinology, Diabetes and Metabolism, NYU Grossman School of Medicine, NY, USA

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