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Hormones and Aging - 1st Edition - ISBN: 9780323855488, 9780323855495

Hormones and Aging, Volume 115

1st Edition

Editor: Gerald Litwack
Hardcover ISBN: 9780323855488
eBook ISBN: 9780323855495
Imprint: Academic Press
Published Date: 26th February 2021
Page Count: 656
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Table of Contents


Gerald Litwack

1. Aging and the hypothalamic-pituitary-thyroid axis

Leonidas H. Duntas

2. Hypothalamic aging and hormones

Zi-Jian Cai

3. Hypothalamic gene transfer of BDNF promotes healthy aging

Lei Cao, Seemaab Ali and Nicholas J. Queen

4. Melatonin and healthy aging

Daniel P. Cardinali

5. Luteinizing hormone and the aging brain

Megan Mey, Sabina Bhatta and Gemma Casadesus

6. Leptin regulation of hippocampal synaptic function in health and disease

Kirsty Hamilton and Jenni Harvey

7. Endocannabinoids and aging—Inflammation, neuroplasticity, mood and pain

Yongsoon Park and Bruce A. Watkins

8. Parathyroid hormone levels and aging: Effect on balance

Lavanya Murthy and Gustavo Duque

9. Insulin and aging

Mirian Ayumi Kurauti, Gabriela Moreira Soares, Carine Marmentini, Gabriela Alves Bronczek, Renato Chaves Souto Branco and Antonio Carlos Boschero

10. Sirtuins and the prevention of immunosenescence

Denise Lasigliè

11. Alterations in cyclic nucleotide signaling are implicated in healthy aging and age-related pathologies of the brain

Nicole Gorny and Michy P. Kelly

12. Aging and FGF23-klotho system

Makoto Kuro-O

13. Aging and sex hormones in males

Maria Chiara Decaroli, Sara De Vincenti and Vincenzo Rochira

14. Sexual dimorphism, aging and immunity

Veena Taneja

15. Hormones and bone loss across the menopause transition

Arun S. Karlamangla, Albert Shieh and Gail A. Greendale

16. Relaxin abrogates genomic remodeling of the aged heart

Guillermo Romero and Guy Salama

17. Role of FoxO transcription factors in aging-associated cardiovascular diseases

Sneha Mishra, Venkatraman Ravi and Nagalingam Ravi Sundaresan

18. Ghrelin and adipokines: An overview of their physiological role, antimicrobial activity and impact on cardiovascular conditions

Luís Perpétuo, Pierre Marie Voisin, Francisco Amado, Christophe Hirtz and Rui Vitorino

19. Sex hormones and cognition in aging

Caroline Gurvich, Jessica Le, Natalie Thomas, Elizabeth H. X. Thomas and Jayashri Kulkarni

20. Role of hormones in sarcopenia

Priego T, Martín AI, González-Hedström D, Granado M, López-Calderón A and Daniel Cardalini

21. Sources of lumbar back pain during aging and potential therapeutic targets

T. Peter Li, Amit Jain and Xu Cao

22. Leydig cell aging: Molecular mechanisms and treatments

V. Papadopoulos and B. Zirkin

23. Adiponectin/AdipoRs signaling as a key player in testicular aging and associated-metabolic disorders

Mayank Choubey, Ashutosh Ranjan and Amitabh Krishna


Hormones and Aging, Volume 115 in the Vitamins and Hormones series, highlights advances in the field, with this new volume presenting timely topics, including hypothalamic aging and hormones, endocannabinoids and aging-inflammation, neuroplasticity, mood and pain, the impact of hormones and bone loss across the menopause transition, and much more.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Vitamins and Hormones series
  • Includes the latest information on Hormones and Aging


Undergraduates, graduates, academics and researchers in the field of vitamins and hormones


No. of pages:
© Academic Press 2021
26th February 2021
Academic Press
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Editor

Gerald Litwack

Gerald Litwack

Dr. Gerald Litwack obtained M.S. and PhD degrees from the University of Wisconsin Department of Biochemistry and remained there for a brief time as a Lecturer on Enzymes. Then he entered the Biochemical Institute of the Sorbonne as a Fellow of the National Foundation for Infantile Paralysis. He next moved to Rutgers University as an Assistant Professor of Biochemistry and later as Associate Professor of biochemistry at the University of Pennsylvania Graduate School of Medicine. After four years he moved to the Temple University School of Medicine as Professor of Biochemistry and Deputy Director of the Fels Institute for Cancer Research and Molecular Biology, soon after, becoming the Laura H. Carnell Professor. Subsequently he was appointed chair of Biochemistry and Molecular Pharmacology at the Jefferson Medical College as well as Vice Dean for Research and Deputy Director of the Jefferson Cancer Institute and Director of the Institute for Apoptosis. Following the move of his family, he became a Visiting Scholar at the Department of Biological Chemistry of the Geffen School of Medicine at UCLA and then became the Founding Chair of the Department of Basic Sciences at the Geisinger Commonwealth School of Medicine, becoming Professor of Molecular and Cellular Medicine and Associate Director of the Institute for Regenerative Medicine at the Texas A&M Health Science Center as his final position. During his career he was a visiting scientist at the University of California, San Francisco and Berkeley, Courtauld Institute of Biochemistry, London and the Wistar Institute. He was appointed Emeritus Professor and/or Chair at Rutgers University, Thomas Jefferson University and the Geisinger Commonwealth School of Medicine. He has published more than 300 scientific papers, authored three textbooks and edited more than sixty-five books. Currently he lives with his family and continues his authorship and editorial work in Los Angeles.

Affiliations and Expertise

Emeritus Professor and/or Chair at Rutgers University, Thomas Jefferson University and the Geisinger Commonwealth School of Medicine, USA; Toluca Lake, North Hollywood, California, USA