
Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques
Kidney, Lung, Heart, Intestine and Mesenteric Lymph Node
Description
Key Features
- Addresses the chronological sequence of tissue alterations following defined radiation doses in rhesus macaques
- Provides photo-documentation of a broad range of histochemical and immunohistochemical stains that illustrate tissue damage and reparative changes following irradiation
- Presents insights into the involvement of various signaling and effector molecules in the development of radiation-associated injury
Readership
Researchers in nonhuman primate radiation (animal science and animal oncology). Radiation oncologists seeking translatable research for humans
Table of Contents
Chapter 1: Kidney
Routine histology stain-
Hematoxylin & eosin
Histochemical stains-
Periodic acid-Schiff/hematoxylin
Phosphotungstic acid/hematoxylin
Chromotrope-aniline blue
Masson’s trichrome
Immunohistochemical stains-
von Willebrand factor
Collagen 1
Alpha smooth muscle actin
Connective tissue growth factor
CD3
CD20
CD31
CD38
CD68
CD163
Myeloperoxidase
Tryptase
Galectin-3
Pro-renin receptorChapter 2: Lung
Routine histology stain-
Hematoxylin & eosin
Histochemical stains-
Masson’s trichrome
Toluidine blue
Immunohistochemical stains-
Collagen 1
Alpha smooth muscle actin
Connective tissue growth factor
CD31
CD163
CD206
Myeloperoxidase
Tryptase
Galectin-3
Transforming growth factor-beta
Caspase 3Chapter 3: Heart
Routine histology stain-
Hematoxylin & eosin
Histochemical stains-
Masson’s trichrome
Immunohistochemical stains-
Caspase 3
Galectin-3
Alpha smooth muscle actinChapter 4: Jejunum
Routine histology stain-
Hematoxylin & eosin
Histochemical stains-
Masson’s trichrome
Alcian blue/periodic acid-Schiff
Immunohistochemical stains-
MxA
Ki67
Connective tissue growth factor
Collagen 1
CD13
CD163
LipopolysaccharideChapter 5: Colon
Routine histology stain-
Hematoxylin & eosin
Histochemical stains-
Masson’s trichrome
Alcian blue/periodic acid-Schiff
Immunohistochemical stains
Ki67
Collagen 1
Connective tissue growth factor
CD163
LipopolysaccharideChapter 6: Mesenteric lymph node
Routine histology stain-
Hematoxylin & eosin
Histochemical stains-
Masson’s trichrome
Immunohistochemical stains-
Collagen 1
Myeloperoxidase
MxA
Lipopolysaccharide
Transforming growth factor-beta
Tryptase
CD163
Product details
- No. of pages: 616
- Language: English
- Copyright: © Academic Press 2022
- Published: July 1, 2022
- Imprint: Academic Press
- Hardcover ISBN: 9780323913935
About the Author
George Parker
Affiliations and Expertise
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