Hematopathology

Hematopathology

Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches

1st Edition - October 29, 2008

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  • Authors: Faramarz Naeim, P. Rao, Wayne Grody
  • eBook ISBN: 9780080919485

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Description

This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review of immunophenotypic, cytogenetic and molecular findings. The text is balanced with large numbers of full color images, graphs, charts, and tables to assist the reader in understanding these highly technical issues.

Key Features

* Emphasizes the immunophenotypic features, cytogenetic studies, and diagnostic molecular aspects of hematology
* Features hundreds of images, charts and tables for the identification of hematologic disorders not only based on histopathologic features, but also with the use of advanced accessory techniques.

Readership

Pathologists, pathology fellows and residents, clinical laboratory pathologists, hematopathologists; hematologists/oncologists and hematology/oncology fellows.

Table of Contents

  • Chapter 1

    STRUCTURE AND FUNCTION OF HEMATOPOIETIC TISSUES

    Faramarz Naeim

    Chapter 2

    PRINCIPLES OF IMMUNOPHENOTYPING

    Faramarz Naeim

    Chapter 3

    PRINCIPLES OF CYTOGENETICS

    Nagesh Rao

    Chapter 4

    PRINCIPLES OF MOLECULAR TECHNIQUES

    Wayne W. Grody, Nagesh Rao, and Faramarz Naeim

    Chapter 5

    MORPHOLOGY OF ABNORMAL BONE MARROW

    Faramarz Naeim

    Chapter 6

    REACTIVE LYMPHADENOPATHIES

    Faramarz Naeim

    Chapter 7

    BONE MARROW APLASIA

    Faramarz Naeim, Nagesh Rao, and Wayne W. Grody

    Chapter 8

    MYELODYSPLASTIC SYNDROMES

    Faramarz Naeim, Nagesh Rao and Wayne W. Grody

    CHAPTER 9

    CHRONIC MYELOPROLIFERATIVE DISEASES

    Faramarz Naeim, Nagesh Rao and Wayne W. Grody

     

    Chapter 10

    MYELODYSPLASTIC/MYELOPROLIFERATIVE DISEASES

    Faramarz Naeim and Nagesh Rao

    Chapter 11

    ACUTE MYELOID LEUKEMIA

    Faramarz Naeim and Nagesh Rao

    Chapter 12

    THE NEOPLASMS OF PRECURSOR LYMPHOBLASTS

    Faramarz Naeim, Nagesh Rao and Wayne W. Grody

    Chapter 13

    ACUTE LEUKEMIAS OF AMBIGUOUS LINEAGE

    Faramarz Naeim

    Chapter 14

    LYMPHOID MALIGNANCIES OF NON-PRECURSOR CELLS

    General Considerations

    Faramarz Naeim, Nagesh Rao and Wayne W. Grody

    Chapter 15

    MATURE B-CELL NEOPLASMS

    Faramarz Naeim, Nagesh Rao and Wayne Grody

    Chapter 16

    PLASMA CELL MYELOMA AND RELATED DISORDERS

    Faramarz Naeim, Nagesh Rao and Wayne Grody

    Chapter 17

    MATURE T-CELL AND NK-CELL NEOPLASMS

    Faramarz Naeim, Nagesh Rao, Sophie Song and Wane Grody

    Chapter 18

    HODGKIN LYMPHOMA

    Sophie Song, Wayne Grody and Faramarz Naeim

Product details

  • No. of pages: 612
  • Language: English
  • Copyright: © Academic Press 2008
  • Published: October 29, 2008
  • Imprint: Academic Press
  • eBook ISBN: 9780080919485

About the Authors

Faramarz Naeim

Dr. Faramarz Naeim is Professor Emeritus of Pathology, David Geffen School of Medicine, UCLA. He graduated from Tehran University School of Medicine and received his training in Pathology at Mallory Institute of Pathology, Boston City Hospital and Department of Pathology at UCLA School of Medicine. He has provided clinical services as a hematopathologist for 43 years, 30 years at UCLA, Department of Pathology and Laboratory Medicine, and 13 years at VA Greater Los Angeles Healthcare System, Department of Pathology and Laboratory Medicine. Dr. Naeim has published several books and book chapters in hematopathology and numerous articles in peer review journals.

Affiliations and Expertise

Professor Emeritus, Department of Pathology, David Geffen UCLA School of Medicine, Hematopathologist, Department of Pathology and Laboratory Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, California

P. Rao

Dr. Rao is an established Elsevier author. Current projects include analysis of cytogenetic abnormalities in Paget's disease patients and analyzing the mouse karyotypes for identifying XXY males among the offspring of female chimeras from embryonic stem-cells. His cytogenetics laboratory is a training site for interested residents, fellows and medical students.

Affiliations and Expertise

Professor, Pathology and Laboratory Medicine, and Pediatrics, Chief, UCLA Cytogenetics Center, David Geffen UCLA School of Medicine, CA, USA

Wayne Grody

Wayne W. Grody, M.D., Ph.D. is a Professor in the Departments of Pathology & Laboratory Medicine, Pediatrics, and Human Genetics at the UCLA School of Medicine. He is the director of the Diagnostic Molecular Pathology Laboratory within the UCLA Medical Center, and is also an attending physician in the Department of Pediatrics, specializing in the care of patients with or at risk for genetic disorders. He has been one of the primary developers of quality assurance and ethical guidelines for DNA-based genetic testing for a number of governmental and professional agencies including the FDA, AMA, CAP, ACMG, ASHG, NCCLS, CDC, NIH-DOE Human Genome Project (ELSI program), and PSRGN. He served as a member of the NIH-DOE Task Force on Genetic Testing, and was the working group chair for development of national guidelines for cystic fibrosis and factor V-Leiden mutation screening. Most recently, he was appointed chair of an Advisory Committee on Genomic Medicine for the entire VA healthcare system. He did his undergraduate work at Johns Hopkins University, received his M.D. and Ph.D. at Baylor College of Medicine, and completed residency and fellowship training at UCLA. He is double board-certified by the American Board of Pathology (Anatomic and Clinical Pathology, Molecular Genetic Pathology) and the American Board of Medical Genetics (Clinical Genetics, Molecular Genetics, and Biochemical Genetics).

Affiliations and Expertise

Professor, Divisions of Medical Genetics and Molecular Diagnostics, Departments of Path. and Lab. Medicine, Pediatrics, and Human Genetics, UCLA School of Medicine, UCLA Institute for Society and Genetics, Director, Molecular Diagnostic Laboratories and Clinical Genomics Center, UCLA Medical Center, Los Angeles, CA, USA

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