Description

This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review of immunophenotypic, cytogenetic and molecular findings. The text is balanced with large numbers of full color images, graphs, charts, and tables to assist the reader in understanding these highly technical issues.

Key Features

* Emphasizes the immunophenotypic features, cytogenetic studies, and diagnostic molecular aspects of hematology * Features hundreds of images, charts and tables for the identification of hematologic disorders not only based on histopathologic features, but also with the use of advanced accessory techniques.

Readership

Pathologists, pathology fellows and residents, clinical laboratory pathologists, hematopathologists; hematologists/oncologists and hematology/oncology fellows.

Table of Contents

Chapter 1

STRUCTURE AND FUNCTION OF HEMATOPOIETIC TISSUES

Faramarz Naeim

Chapter 2

PRINCIPLES OF IMMUNOPHENOTYPING

Faramarz Naeim

Chapter 3

PRINCIPLES OF CYTOGENETICS

Nagesh Rao

Chapter 4

PRINCIPLES OF MOLECULAR TECHNIQUES

Wayne W. Grody, Nagesh Rao, and Faramarz Naeim

Chapter 5

MORPHOLOGY OF ABNORMAL BONE MARROW

Faramarz Naeim

Chapter 6

REACTIVE LYMPHADENOPATHIES

Faramarz Naeim

Chapter 7

BONE MARROW APLASIA

Faramarz Naeim, Nagesh Rao, and Wayne W. Grody

Chapter 8

MYELODYSPLASTIC SYNDROMES

Faramarz Naeim, Nagesh Rao and Wayne W. Grody

CHAPTER 9

CHRONIC MYELOPROLIFERATIVE DISEASES

Faramarz Naeim, Nagesh Rao and Wayne W. Grody

 

Chapter 10

MYELODYSPLASTIC/MYELOPROLIFERATIVE DISEASES

Faramarz Naeim and Nagesh Rao

Chapter 11

ACUTE MYELOID LEUKEMIA

Faramarz Naeim and Nagesh Rao

Chapter 12

THE NEOPLASMS OF PRECURSOR LYMPHOBLASTS

Faramarz Naeim, Nagesh Rao and Wayne W. Grody

Chapter 13

ACUTE LEUKEMIAS OF AMBIGUOUS LINEAGE

Faramarz Naeim

Chapter 14

LYMPHOID MALIGNANCIES OF NON-PRECURSOR CELLS

General Considerations

Faramarz Naeim, Nagesh Rao and Wayne W. Grody

Chapter 15

MATURE B-CELL NEOPLASMS

Faramarz Naeim, Nagesh Rao and Wayne Grody

Chapter 16

PLASMA CELL MYELOMA AND RELATED DISORDERS

Faramarz Naeim, Nagesh Rao and Wayne Grody

Chapter 17

MATURE T-CELL AND NK-CELL NEOPLASMS

Faramarz Naeim, Nagesh Rao, Sophie Song and Wane Grody

Chapter 18

HODGKIN LYMPHOMA

Sophie Song, Wayne Gro

Details

No. of pages:
612
Language:
English
Copyright:
© 2008
Published:
Imprint:
Academic Press
Electronic ISBN:
9780080919485
Print ISBN:
9780123706072

About the authors

Faramarz Naeim

Dr. Naeim has over 25 years practice in bone marrow pathology with several years of experience in flow cytometry. He is the author of numerous research articles and an established Elsevier author. He is a hematopathologist and an internationally known expert in pathology of bone marrow disorders. He is currently the Head of Hematopathology and the Director of Hematopathology Fellowship program at David Geffen School of Medicine, UCLA.

P. Rao

Dr. Rao is an established Elsevier author. Current projects include analysis of cytogenetic abnormalities in Paget's disease patients and analyzing the mouse karyotypes for identifying XXY males among the offspring of female chimeras from embryonic stem-cells. His cytogenetics laboratory is a training site for interested residents, fellows and medical students.

Reviews

"This is a great book for practicing hematologists and medical oncologists as well as trainees and faculty in anatomic and clinical pathology. The writing is crisp, the figures and tables, all in color, are of high quality and informative and the book contains a wealth of information that is not readily available in reference textbooks of hematology, oncology or pathology. I give the book two thumbs up."

-- Robert I. Handin, MD, Senior Physician, Hematology Division, Brigham and Women’s Hospital; Professor of Medicine, Harvard Medical School, Boston, MA, USA

"This book provides both the expert and the novice with the essential materials and didactic support needed to select, understand and interpret critically the vast number cell and tissue analyses now available from hematopathology laboratories. This text takes a commendably practical and clinically oriented approach to understanding the biologic basis of these tests, the technical, biological, and clinical pitfalls involved in their interpretation, and their power in aiding classification, prognostication and treatment selection. This is a very valuable teaching aid and reference volume for advanced students, residents in pathology, hematology oncology fellows, and specialists in blood disorders. The book should also be helpful to basic scientist working in these fields."

--Edward J. Benz, Jr., MD, President, Dana Farber Cancer Institute, Boston, MA, USA

"Hematopathology is a well written and comprehensive text that provides both strong background and specific details regarding hematological malignancies and their diagnosis. The text is easy to read and well organized. There are numerous high quality photomicrographs and comprehensive tables (particularly the cell differentiation molecules table) that complement the text. I particularly liked the background information regarding hematopoietic stem cells, and the practical aspects of the sections describing the