Growth Hormone and Related Proteins

Growth Hormone and Related Proteins

1st Edition - January 28, 1977

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  • Editor: Choh Hao Li
  • eBook ISBN: 9780323159753

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Hormonal Proteins and Peptides, Volume IV: Growth Hormone and Related Proteins deals with various aspects of somatotropin or growth hormone, and its related proteins. This book begins by discussing the bioassay methods for somatotropin, followed by a review of the in vitro lipolytic actions of the hormone. The chemistry of human chorionic somatomammotropin (HCS) and human somatotropin (HGH) are compared and deliberated in detail. This publication concludes with an analysis of the control of prolactin secretion, including an account of the development of the hypophysectomy technique in the rat and effect of hypophysectomy on various bodily functions in experimental animals. This volume is a good reference for endocrinologists, medical practitioners, and researchers conducting work on growth hormones.

Table of Contents

  • List of Contributors


    Contents of Previous Volumes

    1. Bioassay of Pituitary Growth Hormone

    I. Introduction

    II. Weight Increase of Normal Plateaued Rats

    III. Weight Increase of Hypophysectomized Rats

    IV. Weight Increase of Dwarf Mice

    V. Increase in Tail Length of Hypophysectomized Rats

    VI. Increase in the Width of the Proximal Tibial Epiphysis of Hypophysectomized Rats

    VII. The Tibia Test

    VIII. The Tibia Test in Hypophysectomized Mice

    IX. Increase in the Longitudinal Bone Growth of Proximal Tibia in Hypophysectomized Rats

    X. Stimulation of Hepatic Ornithine Decarboxylase Activity

    XI. Stimulation of Sugar Transport in Isolated Diaphragm of Hypophysectomized Rats

    XII. Miscellaneous Methods

    XIII. Concluding Remarks


    Note Added in Proof

    2. Growth Hormone and the Regulation of Lipolysis

    I. Introduction

    II. Demonstration of Involvement of GH in Lipid Mobilization

    III. Physiology of Adipose Tissue and the Importance of Free Fatty Acids

    IV. Effects of GH on FFA Release in Vivo

    V. Stimulation of Lipolysis by GH in Vitro

    VI. Conclusions


    3. The Chemistry of Human Chorionic Somatomammotropin

    I. Introduction

    II. Isolation and Characterization as a Pure Substance

    III. Molecular Properties

    IV. Structure-Function Relationships

    V. Concluding Remarks


    4. Control of Prolactin Secretion

    I. Introduction

    II. Hypothalamic Control

    III. Agents Other than Biogenic Amines That Influence Prolactin Secretion

    IV. Location of Areas of the Brain That Influence Prolactin Secretion and Nervous Pathways Involved

    V. Relation of Prolactin to Secretion of Gonadotropins

    VI. Prolactin Receptor Binding Activity in Different Tissues

    VII. Relation of Prolactin to Secretion of ACTH, GH, and TSH

    VIII. Some Unique Aspects of Control of Prolactin Secretion in Man


    5. Hypophysectomy and Philip E. Smith

    I. Introduction

    II. Amphibian Research

    III. Mammalian Research

    IV. Growth

    V. Pituitary-Thyroid Relationship

    VI. Pituitary-Gonad Relationship

    VII. Monkeys

    VIII. Reflections


    Author Index

    Subject Index

Product details

  • No. of pages: 226
  • Language: English
  • Copyright: © Academic Press 1977
  • Published: January 28, 1977
  • Imprint: Academic Press
  • eBook ISBN: 9780323159753

About the Editor

Choh Hao Li

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