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Green Synthetic Approaches for Biologically Relevant Heterocycles - 2nd Edition - ISBN: 9780128205860

Green Synthetic Approaches for Biologically Relevant Heterocycles

2nd Edition

Volume 1: Advanced Synthetic Techniques

Editor: Goutam Brahmachari
Paperback ISBN: 9780128205860
Imprint: Elsevier
Published Date: 1st February 2021
Page Count: 600
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Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of additional new chapters on hot topics in the field.

Volume 1 explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles, classified on the basis of ring-size and/or the presence of heteratoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions.

Fully revised and updated, Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product, and green chemistry.

Key Features

  • Provides fully updated coverage of the field of greener heterocycle synthesis
  • Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches
  • Presents information in an accessible style with an emphasis on sustainability


Organic, Natural Product, Synthetic and Green Chemists across both academia and industry

Table of Contents

1. Green synthetic approaches for biologically relevant heterocycles: Advanced synthetic techniques – an overview
2. Use of Ball Milling for the Synthesis of Biologically Active Heterocycles
3. High pressure cycloaddition reactions in the synthesis of biologically relevant heterocycles
4. Microwave-induced synthesis of heterocycles of medicinal interests
5. Multicomponent reactions under microwave irradiation: a green path to biologically important heterocycles
6. Application of microwave irradiation in the synthesis of P-heterocycles
7. Green approaches for synthesis and functionalization of indole-based heterocycles of biological relevance
8. Sustainable one-pot domino reactions to access significant heterocycles employing dithioesters and their derivatives
9. Solvent-free synthesis of biologically relevant heterocyclic skeletons
10. Photocatalytic Minisci reaction: A promising and eco-friendly route to functionalize heteroaromatics of biological interest
11. Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds
12. Advances on greener processes for triazole synthesis via azide-alkyne cycloaddition reactions
13. Green Chemistry of Imines in Heterocyclic Synthesis
14. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes
15. Multicomponent approach for the sustainable synthesis of lawsone based heterocycles
16. Sustainable synthesis of Meldrum's acid derived heterocycles via multicomponent reactions


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© Elsevier 2021
1st February 2021
Paperback ISBN:

About the Editor

Goutam Brahmachari

Goutam Brahmachari

Goutam Brahmachari is a professor of organic chemistry at Visva-Bharati, India, and teaches courses in organic chemistry, natural products chemistry, synthetic organic chemistry, and physical methods in organic chemistry. In addition to over 20 years of teaching and research experience, he is a Fellow of the Royal Society of Chemistry, a Who’s Who in the World Listee, and a recipient of Academic Brilliance Award (2015) for Excellence in Research and the Dr. Kalam Best Teaching Faculty Award (2017). Prof. Brahmachari serves as journal referee, editor-in-chief, associate editor, guest editor, and Editorial Advisory Board Member for several international journals, book publishers, and research funding agencies. He currently has 200 publications in the fields of organic and medicinal chemistry, including 22 books and over 40 book chapters, published by internationally reputed publishers.

Affiliations and Expertise

Full Professor of Organic Chemistry, Department of Chemistry, Visva-Bharati (a Central University), Santiniketan, West Bengal, India

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