Green Approaches in Medicinal Chemistry for Sustainable Drug Design - 1st Edition - ISBN: 9780128175927

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

1st Edition

Editors: Bimal Banik
Paperback ISBN: 9780128175927
Imprint: Elsevier
Published Date: 1st April 2020
Page Count: 610
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Table of Contents

Part 1: Green Chemistry
1. Green Chemistry Assisted Synthesis of Natural and Synthetic Compounds as Anticancer Agents
2. Antibacterial and Antimicrobial Coatings on Metal Substrate by Cold Spray Technique: Present and Future Perspectives
3. Graphene Oxide Nanosheets as Sustainable Carbocatalysts: Synthesis of Medicinally Important Heterocycles
4. Sustainable and Green Technologies for Synthesis of Potential Drugs Targeted Towards Tropical Diseases
5. Clay-Mediated Synthesis of Biologically Active Molecules: Green and Sustainable Approaches
6. The Role of Ionic Liquid in Medicinal Chemistry
7. Synthesis of Medicinally Important Heterocycles Inside the Nanoreactors Built in Non-conventional Reaction Media
8. Green Synthesis of Nanoparticles and Nanocomposites: Medicinal Aspects

Part 2: Methods and Synthesis
9. Use of Sustainable Organic Transformations in the Construction of Heterocyclic Scaffolds
10. One-Pot Synthesis of Medicinally Active Compounds
11. Organocatalytic Cycloaddition Reaction: A Gateway for Molecular Complexity
12. Diverse Synthesis of Steroids
13. Reactions in Water: Synthesis of Biologically Active Compounds
14. Solventless Reactions: Green and Sustainable Approaches in Medicinal Chemistry
15. Thiosugars in the Synthesis of Biologically Active Compounds

Part 3: Medicinal Chemistry
16. Implementing Green Chemistry for Synthesis of Cholesterol Lowering Statin Drugs
17. Sustainable Release of Nanodrugs: A New Biosafe Approach
18. Stimuli Responsive Sugar-Derived Hydrogels: A Modern Approach in Cancer Biology
19. Green Synthesis and Biological Evaluation of Anticancer Drugs
20. Green Chemistry and Synthetic Approaches in the Development of Antidepressant and Antipsychotic agents

Part 4: Computers in Drug Discovery
21. Computational Methods and Tools for Sustainable and Green Approaches in Drug Discovery
22. Dipole Moment of Medicinally Active Compounds: A Sustainable Approach

Part 5: Natural Products:
23. Natural Spices in Medicinal Chemistry: Properties and Benefits
24. Medicinal Plants and Their Compounds With Anticancer Properties

Part 6: Microwave-Induced Chemistry:
25. Microwave-Assisted Synthesis of Anti-tubercular Agents: A Novel Approach
26. Microwave-Induced Synthesis of Steroids and Their Chemical Manipulations
27. Microwave-Induced Synthesis as a Part of Green Chemistry Approach for Novel Anti-inflammatory agents


Description

Green Approaches in Medicinal Chemistry for Sustainable Drug Design encourages the growth of green medicinal chemistry by supporting medicinal chemists, drug discovery researchers, pharmacologists, and those in related fields who want to integrate these approaches into their own work. After providing context to the growth of green chemistry in relation to drug discovery, the book identifies a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process.

Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. The book reveals how medicinal chemistry can play a direct role in addressing this issue.

Key Features

  • Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability
  • Reflects on techniques for a broad range of compounds and materials
  • Highlights sustainable and green chemistry pathways for molecular synthesis

Readership

Medicinal Chemists, pharmaceutical scientists, Biotechnologists, Green Chemists and Environmental Chemists working in both academia and industry; Students in related fields; Scientists working in Government Research Agencies; Industrial Scientists starting from Entry Level Professionals to Vice President/President


Details

No. of pages:
610
Language:
English
Copyright:
© Elsevier 2020
Published:
1st April 2020
Imprint:
Elsevier
Paperback ISBN:
9780128175927

Ratings and Reviews


About the Editors

Bimal Banik Editor

Since being awarded his PhD by the Indian Association for the Cultivation of Science, Calcutta, Professor Banik has held positions as a Postdoctoral Fellow at Case Western Reserve University and Stevens Institute of Technology; Tenured Full Professor in Chemistry and First President’s Endowed Professor in Science & Engineering at the University of Texas-Pan American, Edinburg; an Assistant Professor in Molecular Pathology at the University of Texas M. D. Anderson Cancer Center, Houston; and a Research Assistant Professor in Chemistry & Chemical Biology at Stevens Institute of Technology, New Jersey. Since 2014, he has been the Vice President of Research & Education Development of Community Health Systems of South Texas. Professor Banik has designed, synthesized, and identified novel beta lactams derived from polyaromatic compounds as anticancer agents. He is involved in the asymmetric synthesis, biological evaluation, delivery of compounds to increase the effectiveness and mechanism of actions studies of beta lactams and polyaromatic compounds as anticancer agents. Some of his catalytic methods have received exceptional recognitions by the chemical and scientific community. Professor Banik has more than 315 publications to his name and has presided over numerous research sessions at top conferences in the field, including one at the Nobel Prize celebration in Germany.

Affiliations and Expertise

Vice President of Research and Education Development, Community Health Systems of South Texas, USA