Gluten-Related Disorders

Gluten-Related Disorders

Diagnostic Approaches, Treatment Pathways, and Future Perspectives

1st Edition - September 19, 2021

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  • Editor: Mohammad Rostami-Nejad
  • Paperback ISBN: 9780128218464
  • eBook ISBN: 9780128218587

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Gluten-related disorders are prevalent worldwide, especially in developing countries. These diseases have similar clinical manifestations. Although they are characterized by a specific pathophysiological response to ingestion of gluten, differential diagnosis of these disorders is very challenging. Failure to diagnose and treat these disorders at an early stage, can lead to irreparable health and cost damages. Gluten-Related Disorders: Diagnostic Approaches, Treatment Pathways, and Future Perspectives solves this problem by reporting up-to-date scientific findings that allow for faster, more accurate diagnosis of gluten-related disorders as well as guidance on treatment options. By identifying the distinctive features of each of the gluten-related disorders, the chapters lead readers to optimal diagnosis and treatment options as well as better research designs for future research studies on the pathogenesis of these disorders. This reference provided by experts in the field is perfect for researchers, scientists, and medical practitioners who are involved in addressing gluten-related disorders.

Key Features

  • Provides a comprehensive overview on all aspects of gluten-related disorders, incorporating many up-to-date scientific findings
  • Highlights the differences and overlaps in clinical presentations of gluten-related disorders in order to aid differential diagnosis
  • Presents the current understanding of the pathogenesis of gluten-related disorders, which can be used to inform future research endeavors


Researchers, scientist and medical practitioners, universities, research centers and analytical laboratories. Manufacturers of kits for clinical diagnostics

Table of Contents

  • 1. Introduction
    Mohammad Rostami-Nejad

    2. Gluten-related disorders: an evolving story
    Geoffrey Kenneth Towndrow Holmes

    3. Gluten and its main food sources and other components of grains that may impact on health
    Justine Bold

    4. Gluten-related disorders definition
    Nastaran Asri and Mohammad Rostami-Nejad

    5. Epidemiology and burden of gluten-related disorders
    Mohamad Amin Pourhoseingholi

    6. Genetic and environmental factors of gluten related disorders
    Hamed Mirjalali and Sajad Tavakoli

    7. Pathomechanism of gluten-related disorders
    Anupam Rej and David Surendran Sanders

    8. Clinical features of GRDs
    Carolina Ciacci

    9. Histopathologic aspects of gluten-related disorders
    Arzu Ensari, Cevriye Cansiz Ersoz, Ayca Kirmizi and Saba Kiremitci

    10. Diagnosis of gluten-related disorders
    Mihai Danciu and Ion Negura

    11. Treatment of gluten-related disorders
    Shakira Yoosuf and Govind K. Makharia

    12. Comorbidities associated with celiac disease, dermatitis hepetiformis and nonceliac gluten sensitivity
    Geoffrey Kenneth Towndrow Holmes

    13. Gluten-related disorders: monitoring and follow-up
    Abdulbaqi Al-Toma and Chris Mulder

    14: Refractory celiac disease
    Abdulbaqi Al-Toma

    15: Summary of tables and figures
    Mohammad Rostami-Nejad and Nastaran Asri

    16: Conclusion and insights
    Mohammad Rostami-Nejad and Nastaran Asri

Product details

  • No. of pages: 300
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: September 19, 2021
  • Imprint: Academic Press
  • Paperback ISBN: 9780128218464
  • eBook ISBN: 9780128218587

About the Editor

Mohammad Rostami-Nejad

Mohammad Rostami-Nejad, PhD is the head of the Celiac Disease Department in the Research Institute for Gastroenterology and Liver Diseases (RIGLD) at the Shahid Beheshti University of Medical Sciences. His major areas of research include clinical immunology, especially for celiac disease and other gluten-related disorders. He has collaborated with various national and international centers and universities. Additionally, he has taken part in more than 60 projects as well as published 200 scientific papers, books, and book chapters on celiac disease (H-index=27). He initiated the first celiac diseases website in Persian ( and is the Deputy Editor of the Gastroenterology and Hepatology From Bed to Bench (GHFBB) journal.

Affiliations and Expertise

Department of Celiac disease, Research Institute for Gastroenterology and Liver Diseases (RIGLD), Shahid Beheshti University of Medical Sciences, Iran

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