Genetics of Sex Differentiation - 1st Edition - ISBN: 9780125010405, 9780323158503

Genetics of Sex Differentiation

1st Edition

Authors: Ursula Mittwoch
eBook ISBN: 9780323158503
Imprint: Academic Press
Published Date: 1st January 1973
Page Count: 268
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Genetics of Sex Differentiation intends to help readers understand the genetic basis of sex differentiation. The book focuses on explaining how the sex chromosomes affect the process of sex differentiation by influencing the rates at which cells divide.

The book is composed of seven chapters. It provides overviews of classical genetics and structure of cells. It also explains the chromosomal basis of sex determination and sex determination using Drosophila. Polygenetics and continuous and quasicontinuous variations are also discussed. The book also discusses sex factors, determination, and disorders. Moreover, it explains the heterochromatin, embryological basis of sex differentiation, and triploidy and autosomal effects. In addition, it discusses the relationship of genes, chromosomes, growth, and sex. The book is an excellent ""bedside book"" for students in biology, specifically in genetics and developmental biology. Lecturers and professionals in biology and genetics will also find this book invaluable for their practice.

Table of Contents


Chapter 1 Classical Genetics of Sex Differentiation

I. Introduction

II. The Structure of Cells

III. The Chromosomal Basis of Sex Determination

IV. The Genetic Evidence

V. Female Heterogamety

VI. The Relationship of Genes and Chromosomes

VII. Sex Determination in Drosophila

VIII. Intersexes in Lymantria

IX. The Theory of Genie Balance

Chapter 2 Genetics of Continuous Variation

I. Introduction

II. Major Genes with Minor Effects

III. Quasicontinuous Variation

IV. Polygenes

Chapter 3 Aspects of the Gene

I. Introduction

II. The Gene before 1950

III. DNA and the Molecular Gene

Chapter 4 Heterochromatin

I. Introduction

II. Heteropycnosis

III. Genetic Effects

IV. Minutes and Homoeotic Mutants in Drosophila

V. Nucleolar Organizers

VI. Repetitive DNA Sequences

VII. B Chromosomes

VIII. Variegated-Type Position Effect

IX. Sex Chromosomes in Interphase

X. Single Active X Chromosome Hypothesis

XI. Autoradiography

XII. Fluorescence Microscopy

XIII. Selective Giemsa Staining

XIV. Constitutive and Facultative Heterochromatin

Chapter 5 The Nature of Sex Differentiation with Special Reference to Vertebrates

I. Introduction

II. Germ Cells

III. Mammalian Gonads

IV. Sex Differentiation in Other Vertebrates

V. Sex Determination in Fish

VI. Induced Sex Reversal

VII. Embryological Basis of Sex Differentiation

VIII. Sex Determination in Three Invertebrates

IX. Sex Factors in Bacteria

Chapter 6 Sex Determination in Man and Other Mammals

I. Introduction

II. Klinefelter's and Turner's Syndromes

III. Females with Multiple X Chromosomes and Males with XYY Chromosomes

IV. The Male-Determining Function of the Mammalian Y Chromosomes

V. XX Males

VI. True Hermaphroditism

VII. Gonadal Dysgenesis

VIII. Testicular

IX. Tumors Affecting the Secondary Sexual

X. Triploidy and Other Autosomal

XI. Sex Chromosomes in Other

XII. Sex Chromosome

XIII. The Freemartin

XIV. Autosomal Sex

Chapter 7 Genes, Chromosomes, Growth, and Sex

I. Introduction

II. Homoeotic Mutants in Drosophila

III. Phenocopies

IV. Genetic Assimilation

V. Transdetermination in Drosophila

VI. Mitotic Rates and Differentiation

VII. Chromosomal Volumes and Mitotic Rates

VIII. Chromosome Puffs, Lampbrush Chromosomes, and the Y Chromosomes in Drosophila

IX. Changes in Karyotypes and Mitotic Rates

X. The Hierarchy of Genetic Elements

XI. Possible Functions of Nongenic DNA

XII. Sex Differentiation and Growth


Author Index

Subject Index


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© Academic Press 1973
Academic Press
eBook ISBN:

About the Author

Ursula Mittwoch

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