Gastrointestinal Defence Mechanisms

Gastrointestinal Defence Mechanisms

Satellite Symposium of the 28th International Congress of Physiological Sciences, Pécs, Hungary, 1980

1st Edition - January 1, 1981

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  • Editors: Gy. Mózsik, O. Hänninen, T. Jàvor
  • eBook ISBN: 9781483190181

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Advances in Physiological Sciences, Volume 29: Gastrointestinal Defence Mechanisms is a collection of papers that details the findings of research studies on the theoretical and practical aspects of the gastrointestinal defense mechanisms. The title first covers circulation and mucosal defense, and then proceeds to tackling the association of gastrointestinal mechanisms with the secretory functions. Next, the selection deals with the resistance in gastric mucosa and mucosal energy provision. The text also discusses cell renewal and toxicity, along with biotransformation and nutrition. In Part VII, the title details the immunomechanisms of defense at mucosa. The last part covers the second line defense at liver and enterohepatic circulation. The book will of great interest to both researchers and practitioners of medical fields concerned with the digestive system.

Table of Contents

  • Preface

    Welcoming Address

    Circulation and Mucosal Defense

    Circulatory Responses to Changes of Intestinal Contents

    The Role of the Microcirculation in the Gastrointestinal Defense Mechanism

    Impaired Defense Mechanism to Peptic Ulcer in the Capsaicin-Desensitized Rat

    Defense and Secretory Functions

    Pseudocholinesterase Activity in Human Oral Fluid

    Regulation of Water Flux across Isolated Gastric Mucosa

    Test of Connection between Hypersecretion Produced Extragastric Stimulus and Sodium Metabolism

    Effect of Somatic Stimulus on the Acid Secretion Activity in Male and Female Rats

    Role of the Functional State of the Gastric Mucosa in Relation to Development of Epinephrine Effects on Rat Stomach

    The Effects of Atropine, Carbenoxolone, Atropine plus Carbenoxolone on the Gastric Acid Secretion and on the Aspirin-Induced Mucosal Damage in Rats

    Role of the Acute Starvation on the Development of Different Experimental Ulcers in the Rat

    Analysis of the Inhibitory Effect of Pelsonin (1:10 Combination of Indomethacin and Sodium-Salicylate) on Shay-Ulcer

    The Effect of Intraduodenal Hypertonic Glucose on the Gastric Mucosal Barrier

    Resistance in Gastric Mucosa

    Gastric Mucosal Resistance to Physical and Chemical Stress

    Pathophysiology of Gastrointestinal Mucins

    The Effect of Different Prostaglandins on Restrain Ulcer of Rat

    Is Cyclic AMP the Mediator of Cytoprotection by Prostaglandins in Human Gastric Mucosa

    Mucosal Energy Provision

    Gastric and Small Intestinal Energy Metabolism in Mucosal Damage

    Biochemical Aspects of Cytoprotective Effect of Prostacyclin on the Rats' Gastric Mucosal Damage Induced By Topical HCl

    Effect of Noise Exposure on the Phosphate Metabolism of Gastric Mucosa

    Cell Renewal and Toxicity

    The Three-Compartmental Enzyme System of the Enterocyte Relating to Its Digestive and Barrier Functions

    The Effect of Cytostatics on Intestinal Protein Loss in Rats

    Biological Model System for Investigating Gastrointestinal Side Effects Caused By Cytostatic Agents

    Effect of Dianhydrogalactitol on Biochemical and Morphological Characteristics of the Rat Intestinal Mucosa

    Biotransformation and Nutrition

    Mucosal Biotransformation and Metabolic Gradients in the Intestine

    Adaptation of Intestinal Biotransformation to Nutritional Variation

    Use of Explant Cultures to Study the Metabolism of Polycyclic Aromatic Hydrocarbons in the Human Gastrointestinal Tract

    The Activity of Epoxidehydratase in Human Colon from Biopsy Tissues

    Effect of Polycyclic Aromatic Hydrocarbons on Carboxylesterase Activity in Rat Liver and Duodenum

    Drug Metabolizing Enzyme Activities in Rats Exposed to Chlorinated Phenols

    Xenobiotic Metabolism in Rainbow Trout Intestine

    Immunomechanisms on Defense at Mucosa

    The Role of the Microbial Flora in the Development, Maintenance and Modulation of Host Immune Functions

    Immune Regulation Function of Gastrointestinal Tract. Disorders with Connection of Impaired Immune Regulation

    The Local Immunity Is a Part of the Gastrointestinal Defense Mechanism

    Some Antimicrobial Defense Mechanisms of the Upper Digestive Tract

    Second Line Defense at Liver and Enterohepatic Circulation

    Biliary Excretion of Xenobiotics

    Fecal Excretion of Digitoxin Metabolites in Germfree (GF) and Conventional (CV) Rats

    Effect of D-Glucaro-L,4-Lactone and Antibiotic Ingestion on the Fecal Excretion of Imipramin and Iopanoic Acid


Product details

  • No. of pages: 606
  • Language: English
  • Copyright: © Pergamon 1981
  • Published: January 1, 1981
  • Imprint: Pergamon
  • eBook ISBN: 9781483190181

About the Editors

Gy. Mózsik

O. Hänninen

Affiliations and Expertise

University of Kuopio, Department of Physiology, PO Box 1627, SF 70211 Kuopio, Finland

T. Jàvor

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