Gastric Secretion

Gastric Secretion

Mechanisms and Control

1st Edition - January 1, 1967

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  • Editors: T. K. Shnitka, J. A. L. Gilbert, R. C. Harrison
  • eBook ISBN: 9781483186177

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Gastric Secretion: Mechanism and Control covers the proceedings of the symposium held at The Faculty of Medicine, University of Alberta, Edmonton, Canada, on September 13-15, 1965. This compilation mainly focuses on the study of gastric secretion and other biological processes involved. This book is divided into seven parts, beginning with discussions on the anatomy and purpose of gastric mucosa. How the gastrointestinal tract is renewed physiologically is also examined. This text then gives information on the regulation, metabolism, and other biological processes in this organ. This book also specifically explains secretion and its stimulation and inhibition. Parts in this book also tackle gastrin and mucus, as well as the neuro-endocrine control. This text ends with concluding remarks, encouraging further studies of the subject. This selection will be invaluable to students of medicine and biology, as well as specialists of gastrointestinal system.

Table of Contents

  • Contributors





    I. Structure and Function

    The Fine Structure of the Gastric Mucosa

    Mitotic Homeostasis and Physiological Control of Cell Renewal in Healthy and Diseased Gastric Mucosa

    Observations on the Regulation of the Growth of the Gastric Mucosa

    The Metabolism of Gastric Mucosa during the Secretion of Hydrochloric Acid

    Recent Observations on Gastric Blood Flow and Acid Secretion

    II. Neuro-Endocrine Control

    The Nerve Supply of the Stomach and Its Relationship to Secretion

    Vagal Effects on Gastric Secretion

    Neural Factors in the Control of Gastrin Release

    Vagal Influences on the Gastrin Content of Antral Mucosa

    Magnitude of the Antrum's Role in the Cephalic Phase of Gastric Secretion

    The Late Acid Response to Insulin Induced Hypoglycaemia and Its Relation to Vagal Stimulated Gastrin Release

    Hypothalamic Influence on Gastric Blood Flow, Cell Counts, Acid and Mucus Secretion—Factors in Ulcer Provocation

    III. Mucus

    Regulation of Gastric Mucus Secretion

    Fractionation of Gastric Macromolecular Materials by Electrophoresis, Column Chromatography and Gel Filtration; Correlative Study

    Stimuli for Gastric Mucus Secretion

    Mucus Content of Gastric Juice during the Secretory Period

    Intrinsic Factor Secretion

    IV. Secretion: Stimulation

    Gastric Secretion and Duodenal Ulcer

    Some Aspects of the Humoral Mechanism of Gastric Secretion

    The Effects of Tissue Extracts on the Stomach

    The Role of Intestinal Digestion in the Control of Acid Secretion

    Considerations on the Effect of Obstruction on Gastric Secretion

    V. Gastrin

    The Constitution and Properties of Gastrin

    Some Physiological Actions of Gastrin

    The Action of Gastrin II on Gastric Secretion of Electrolytes and Pepsin in Man

    Action of Purified Gastrin Polypeptide on the Isolated Gastric Mucosa of the Bullfrog

    Failure of Gastrin Inactivation by the Liver

    Further Observations on Factors influencing the Symptomatology Manifest by Patients with the Zollinger-Ellison Syndrome

    VI. Secretion: Inhibition

    The Recognition and Assay of Gastrone

    Fractionation of Endogenous Inhibitors of Gastric Secretion (Gastrone) by Physico-Chemical Means

    Duodenal Inhibition of Gastric Secretion

    Endocrine and Exocrine Studies on Homotransplanted Gastric Pouches

    Enterogastrone—A Reappraisal of the Problem

    VII. Concluding Remarks

    Concluding Remarks

    Bibliography: Current Monographs on the Physiology of Gastric Secretion


Product details

  • No. of pages: 520
  • Language: English
  • Copyright: © Pergamon 1967
  • Published: January 1, 1967
  • Imprint: Pergamon
  • eBook ISBN: 9781483186177

About the Editors

T. K. Shnitka

J. A. L. Gilbert

R. C. Harrison

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