G Protein-Coupled Receptors - Part A

G Protein-Coupled Receptors - Part A

1st Edition - December 1, 2022

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  • Editor: Arun K. Shukla
  • Hardcover ISBN: 9780323994316

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G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes.

Key Features

  • Covers a broad range of topics related to GPCR activation and signaling
  • Covers several receptor systems with an emphasis on emerging paradigms
  • Covers different processes and model systems with a focus on GPCRs


Scientists interested in learning about the latest developments in the field of GPCR biology and drug discovery

Table of Contents

  • Preface

    Arun K. Shukla

    1. Computational and experimental approaches to probe GPCR activation and signaling

    Paulina Dragan, Alessandro Atzei, Swapnil Ganesh Sanmukh and Dorota Latek

    2. Adrenergic receptors in breast cancer

    Cecilia Pérez Piñero, Ezequiel Mariano Rivero, Lucía Gargiulo, María Sol Rodríguez, Carlos David Bruque, Ariana Bruzzone and Isabel Alicia Lüthy

    3. Tools for adapting to a complex habitat: G-protein coupled receptors in Trichoderma

    Monika Schmoll and Wolfgang Hinterdobler

    4. Targeting G protein-coupled receptors for alleviating neuropathic pain

    Poonam Kumari, Anubhav Yadav, Monika Patel and Prem N. Yadav

    5. Crosstalk between neurons and glia through G-protein coupled receptors: Insights from Caenorhabditis elegans

    Pratima Pandey, Gazaldeep Kaur and Kavita Babu

    6. Cardiovascular GPCR regulation by regulator of G protein signaling proteins

    Anastasios Lymperopoulos, Malka S. Suster and Jordana I. Borges

    7. The interaction, mechanism and function of GPR158-RGS7 cross-talk

    Shradha Darira and Laurie P. Sutton

    8. Taste GPCRs and their ligands

    Nitzan Dubovski, Fabrizio Fierro, Eitan Margulis, Yaron Ben Shoshan-Galeczki, Lior Peri and Masha Y. Niv

    9. Palmitoylation and G-protein coupled receptors

    Georges Chaloub and Peter J. McCormick

Product details

  • No. of pages: 230
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: December 1, 2022
  • Imprint: Academic Press
  • Hardcover ISBN: 9780323994316

About the Serial Volume Editor

Arun K. Shukla

Arun K. Shukla
Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla’s research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.

Affiliations and Expertise

Indian Institute of Technology, Kanpur, India

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